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The map label for this gene is phaC [H]

Identifier: 222095050

GI number: 222095050

Start: 1378418

End: 1379503

Strand: Direct

Name: phaC [H]

Synonym: BCQ_1390

Alternate gene names: 222095050

Gene position: 1378418-1379503 (Clockwise)

Preceding gene: 222095049

Following gene: 222095051

Centisome position: 26.44

GC content: 38.03

Gene sequence:

>1086_bases
ATGACTACATTCGCAACAGAATGGGAAAAGCAATTAGAGCTATACCCAGAAGAGTACCGAAAAGCATATCGCCGAGTGAA
AAGGGCGAGTGAAATTTTATTACGTGAACCAGAGCCACAAGTAGGATTAACGCCGAAAGAGGTTATTTGGACGAAGAATA
AGACGAAGCTTTATCGCTACATTCCAAAACAAGAAAAAACACAAAGAGTCCCAATTCTATTAATATATGCTCTTATTAAT
AAACCATATATTATGGATTTAACTCCTGGAAATAGTTTAGTGGAATATTTAGTGGACCGTGGTTTTGATGTGTATATGCT
TGATTGGGGCACATTTGGTTTAGAAGATAGTCATTTGAAATTTGATGATTTTGTGTTTGATTATATTGCAAAAGCAGTGA
AAAAAGTAATGCGAACTGCAAAATCGGACGAGATTTCTTTACTTGGTTATTGCATGGGGGGAACGCTAACTTCTATTTAT
GCGGCACTTCATCCGCACATGCCAATTCGTAACCTAATCTTTATGACAAGTCCTTTTGATTTCTCTGAAACAGGATTATA
TGGTCCTTTATTAGATGAGAAATACTTCAATCTAGATAAAGCGGTTGATACATTTGGAAATATTCCGCCAGAAATGATTG
ATTTCGGAAACAAAATGTTAAAACCAATTACGAACTTTGTTGGTCCATATGTTGCTTTAGTAGATCGTTCAGAGAATGAG
CGCTTCGTTGAAAGCTGGAGGTTAGTTCAAAAGTGGGTTGGCGATGGCATTCCGTTCCCAGGTGAATCATACAGACAGTG
GATTCGTGATTTTTATCAAAATAATAAATTGGTTAAGGGTGAACTCGTTATTCGCGGACAAAAGGTAGACCTTGCAAATA
TTAAGGCGAATGTCTTAAATATTTCAGGGAAACGTGATCATATCGCCCTGCCGTGCCAAGTAGAAGCGTTGCTAGATCAT
ATTTCTAGCACAGATAAACAATATGTATGTTTACCAACGGGACATATGTCGATTGTTTACGGTGGAACAGCGGTAAAACA
AACGTATCCGACGATTGGAGACTGGCTTGACGAGCGCTCTAAGTAA

Upstream 100 bases:

>100_bases
GGCGGATTATATATGTAATGAAGTAAGAAAAAAGTGCATATCCATAGCAGGAATGCACTTCTTTTTTTAGAAGGAAATTG
ACCAAAAAGGAGATAGAAAA

Downstream 100 bases:

>100_bases
AAATAAAAAATCCAACTAGCATGTGTTAGTTGGATTTTTTTTATGTAAAATAACAAAACATAGAAAGGAGAAATTTATAT
TTTAGGAGTATAATTATGAA

Product: poly(r)-hydroxyalkanoic acid synthase, class iii, phac subunit

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTTFATEWEKQLELYPEEYRKAYRRVKRASEILLREPEPQVGLTPKEVIWTKNKTKLYRYIPKQEKTQRVPILLIYALIN
KPYIMDLTPGNSLVEYLVDRGFDVYMLDWGTFGLEDSHLKFDDFVFDYIAKAVKKVMRTAKSDEISLLGYCMGGTLTSIY
AALHPHMPIRNLIFMTSPFDFSETGLYGPLLDEKYFNLDKAVDTFGNIPPEMIDFGNKMLKPITNFVGPYVALVDRSENE
RFVESWRLVQKWVGDGIPFPGESYRQWIRDFYQNNKLVKGELVIRGQKVDLANIKANVLNISGKRDHIALPCQVEALLDH
ISSTDKQYVCLPTGHMSIVYGGTAVKQTYPTIGDWLDERSK

Sequences:

>Translated_361_residues
MTTFATEWEKQLELYPEEYRKAYRRVKRASEILLREPEPQVGLTPKEVIWTKNKTKLYRYIPKQEKTQRVPILLIYALIN
KPYIMDLTPGNSLVEYLVDRGFDVYMLDWGTFGLEDSHLKFDDFVFDYIAKAVKKVMRTAKSDEISLLGYCMGGTLTSIY
AALHPHMPIRNLIFMTSPFDFSETGLYGPLLDEKYFNLDKAVDTFGNIPPEMIDFGNKMLKPITNFVGPYVALVDRSENE
RFVESWRLVQKWVGDGIPFPGESYRQWIRDFYQNNKLVKGELVIRGQKVDLANIKANVLNISGKRDHIALPCQVEALLDH
ISSTDKQYVCLPTGHMSIVYGGTAVKQTYPTIGDWLDERSK
>Mature_360_residues
TTFATEWEKQLELYPEEYRKAYRRVKRASEILLREPEPQVGLTPKEVIWTKNKTKLYRYIPKQEKTQRVPILLIYALINK
PYIMDLTPGNSLVEYLVDRGFDVYMLDWGTFGLEDSHLKFDDFVFDYIAKAVKKVMRTAKSDEISLLGYCMGGTLTSIYA
ALHPHMPIRNLIFMTSPFDFSETGLYGPLLDEKYFNLDKAVDTFGNIPPEMIDFGNKMLKPITNFVGPYVALVDRSENER
FVESWRLVQKWVGDGIPFPGESYRQWIRDFYQNNKLVKGELVIRGQKVDLANIKANVLNISGKRDHIALPCQVEALLDHI
SSTDKQYVCLPTGHMSIVYGGTAVKQTYPTIGDWLDERSK

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010125 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 41682; Mature: 41550

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFATEWEKQLELYPEEYRKAYRRVKRASEILLREPEPQVGLTPKEVIWTKNKTKLYRY
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCCHHHHHC
IPKQEKTQRVPILLIYALINKPYIMDLTPGNSLVEYLVDRGFDVYMLDWGTFGLEDSHLK
CCCCCCCCCCHHHEEEHHHCCCEEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
FDDFVFDYIAKAVKKVMRTAKSDEISLLGYCMGGTLTSIYAALHPHMPIRNLIFMTSPFD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHCCCCCHHHEEEEECCCC
FSETGLYGPLLDEKYFNLDKAVDTFGNIPPEMIDFGNKMLKPITNFVGPYVALVDRSENE
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCH
RFVESWRLVQKWVGDGIPFPGESYRQWIRDFYQNNKLVKGELVIRGQKVDLANIKANVLN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCEEHHHCEEEEEE
ISGKRDHIALPCQVEALLDHISSTDKQYVCLPTGHMSIVYGGTAVKQTYPTIGDWLDERS
ECCCCCCEECCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHCCCCHHHHHHHCC
K
C
>Mature Secondary Structure 
TTFATEWEKQLELYPEEYRKAYRRVKRASEILLREPEPQVGLTPKEVIWTKNKTKLYRY
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCCHHHHHC
IPKQEKTQRVPILLIYALINKPYIMDLTPGNSLVEYLVDRGFDVYMLDWGTFGLEDSHLK
CCCCCCCCCCHHHEEEHHHCCCEEEEECCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
FDDFVFDYIAKAVKKVMRTAKSDEISLLGYCMGGTLTSIYAALHPHMPIRNLIFMTSPFD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHCCCCCHHHEEEEECCCC
FSETGLYGPLLDEKYFNLDKAVDTFGNIPPEMIDFGNKMLKPITNFVGPYVALVDRSENE
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCH
RFVESWRLVQKWVGDGIPFPGESYRQWIRDFYQNNKLVKGELVIRGQKVDLANIKANVLN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCEEHHHCEEEEEE
ISGKRDHIALPCQVEALLDHISSTDKQYVCLPTGHMSIVYGGTAVKQTYPTIGDWLDERS
ECCCCCCEECCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHCCCCHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1396692 [H]