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The map label for this gene is resD [H]

Identifier: 222095033

GI number: 222095033

Start: 1364068

End: 1364739

Strand: Direct

Name: resD [H]

Synonym: BCQ_1373

Alternate gene names: 222095033

Gene position: 1364068-1364739 (Clockwise)

Preceding gene: 222095032

Following gene: 222095034

Centisome position: 26.16

GC content: 36.76

Gene sequence:

>672_bases
ATGAGTAAATATAGGGTGCTAGTTGTAGATGATGAAAGTGATATGAGGCAACTTGTTGGAATGTACTTAGATAATTTCGG
ATACGAGTGGGGAGAAGCTGAAAATGGAAAAGAAGCTCTAAAAAAATTAGAGACAAATCATTATGATTTCGTTGTACTAG
ATATTATGATGCCAGAGATGGATGGACTTTCAGTTTGTAAAGAAATTAGAAAAACGTCAGATGTACCAATAATATTTTTA
ACAGCAAAAGGTGAAGAGTGGAATAGGGTGAACGGCTTACGTATGGGAGCAGATGATTATATTGTAAAGCCATTTAGTCC
TGGCGAATTAATTGCTCGTATGGAAGCTGTATTAAGGCGTTATACAAAGCAAGAGCAACAAGAGGAATTTCAGTTTGGAC
CGATCCTTATTAATGAAAAAAGTAGGAAAATTGAGGTGGATGGTGAGCCAATTTCTCTTACAGTAAAAGAGTTTGATTTA
CTCTATTTTCTTTGCCAACATACAGGACAAGTATTTAGCCGAGAACAATTGCTGGAAAAGGTATGGGGATATGATTATGC
CGGAAGTACAAGAACCGTAGATACGCACGTGAAAACGATGCGTTTGAAGCTTGGAGAAAGTGGAAACTACATTCAAACTG
TTTGGGGTGTAGGATATAAATTTGAGGTGTAA

Upstream 100 bases:

>100_bases
GATGAAGTGTGCGTCATGGATATGAAGAATTTGAAAATAAAACAAACAATTAAAGTCGGAAAAGGACCGTTTCAACTCAT
AGAGAGAGAAGGGAAGGACA

Downstream 100 bases:

>100_bases
CGTATGTTTACGATGGTACAGAAGCTTTGGCTGACAGTAGTATGTGCAGTATTTGTAACAGTTTCCTTTCTTTATTTTGT
ATCTTTATACTCGTATGAAA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETNHYDFVVLDIMMPEMDGLSVCKEIRKTSDVPIIFL
TAKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLRRYTKQEQQEEFQFGPILINEKSRKIEVDGEPISLTVKEFDL
LYFLCQHTGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV

Sequences:

>Translated_223_residues
MSKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETNHYDFVVLDIMMPEMDGLSVCKEIRKTSDVPIIFL
TAKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLRRYTKQEQQEEFQFGPILINEKSRKIEVDGEPISLTVKEFDL
LYFLCQHTGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV
>Mature_222_residues
SKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETNHYDFVVLDIMMPEMDGLSVCKEIRKTSDVPIIFLT
AKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLRRYTKQEQQEEFQFGPILINEKSRKIEVDGEPISLTVKEFDLL
YFLCQHTGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=40.0900900900901, Blast_Score=174, Evalue=3e-45,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=40.3587443946188, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.9122807017544, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=36.9369369369369, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=36.4444444444444, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=35.3211009174312, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=31.9634703196347, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.3982300884956, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=35.3211009174312, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=32.7272727272727, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.3275862068966, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=30.0448430493274, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=31.0810810810811, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=30.4347826086957, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788550, Length=146, Percent_Identity=36.3013698630137, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=37.5, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=35.2380952380952, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=35.2941176470588, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=121, Percent_Identity=30.5785123966942, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25867; Mature: 25736

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETNHYDFVVLDIMMPEM
CCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCC
DGLSVCKEIRKTSDVPIIFLTAKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHH
YTKQEQQEEFQFGPILINEKSRKIEVDGEPISLTVKEFDLLYFLCQHTGQVFSREQLLEK
HHHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV
HCCCCCCCCCEEHHHHHEEEEEEECCCCCEEEHEECCCEEECC
>Mature Secondary Structure 
SKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETNHYDFVVLDIMMPEM
CCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCC
DGLSVCKEIRKTSDVPIIFLTAKGEEWNRVNGLRMGADDYIVKPFSPGELIARMEAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHH
YTKQEQQEEFQFGPILINEKSRKIEVDGEPISLTVKEFDLLYFLCQHTGQVFSREQLLEK
HHHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV
HCCCCCCCCCEEHHHHHEEEEEEECCCCCEEEHEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]