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The map label for this gene is ygbD [C]

Identifier: 222094978

GI number: 222094978

Start: 1303398

End: 1304696

Strand: Direct

Name: ygbD [C]

Synonym: BCQ_1316

Alternate gene names: 222094978

Gene position: 1303398-1304696 (Clockwise)

Preceding gene: 222094977

Following gene: 222094979

Centisome position: 25.0

GC content: 38.26

Gene sequence:

>1299_bases
ATGAGTGCAGCGATGCAAATTGTTAGAAACGATGAAAATGCAAATGTTGTGACGTTAGAAAAAGGTGAAATTTATTCGTA
CGCGCAGTGTGGGTTACCGTATGTCATTAGTGGTGCTATCGCTTCAACGGAAAAGTTAATCGCGCGTAATGTAAAGATGT
TTCGTGATAAATACGGAATTGATGCGAAAGTACGACATGAAGTAACGAAAGTAGATACGGAAAAGAAAATGGTATACGCA
GAGCATACGAAGACGAAAGATATCTTTGAATTTTCGTATGACCGTTTATTAATTGCGACCGGAGTACGTCCTGTTATGCC
AGAATGGGAAGGGCGAGATTTACAAGGCGTTCATCTTTTAAAAACAATTCCGGATGCTGAGCGCATATTAAAAACGCTAG
AAACGAATAAAGTTGAAGATGTAACTATTATTGGCGGCGGTGCAATTGGGCTTGAGATGGCAGAAACATTCGTTGAACTT
GGTAAAAAAGTAAGAATGATTGAGCGAAATGATCATATTGGTACCATTTATGATGCGGATATGGCGGAGTATATACATAA
AGAAGCAGATAAACATCATATTGAAATTTTAACGAATGAAAATGTAAAAGCGTTTAAAGGGAATGAACGAGTAGAAGCAG
TTGAAACGGATAAAGGTACGTATAAAGCGGATCTTGTTCTAGTATCTGTCGGAGTGAAGCCGAATACTGATTTTCTTGAA
GGAACGAATATACGTACAAATCATAAAGGGGCAATCGAGGTAAATGCATATATGCAAACGAATGTGCAAGACGTATATGC
AGCTGGTGATTGTGCGACACATTATCACGTTATAAAAGAAATTCATGATCATATTCCAATTGGAACAACTGCAAATAAAC
AAGGGCGACTTGCTGGACTGAATATGCTGGATAAACGAAGAGCTTTTAAAGGAACGTTGGGTACAGGCATTATTAAATTT
ATGAATTTGACGCTCGCAAGAACAGGCTTAAATGAAAAGGAAGCAAAAGGATTACATATCCCGTATAAAACAGTCAAAGT
AGATTCGACAAATATGGCGGGCTATTATCCAAATGCGAAACCACTTTACTTGAAATTACTATACCGTTCTGACACGAAAC
AATTATTAGGTGGACAAGTAATTGGAGAAGAAGGTGTAGATAAACGGATTGATGTGATCGCAATGGCACTCTTCAATAAA
ATGAGCATTCACGATTTAGAAGATGTGGACTTAAGTTATGCACCACCATATAACAGCGTTTGGGATCCAATTCAGCAAGC
GGCAAGACGAGCGGAATAG

Upstream 100 bases:

>100_bases
GTAGGTGTTATTTCTATAAAATATGGAAAACGTAAAGAGTATGTAAAAAAGAAGGAGTGGTAAAGTGAACTATGTCATTA
TTGGCGGAGATGCAGCTGGT

Downstream 100 bases:

>100_bases
CACTTTTTAAGTGCTATTTTTTTCGTTAAAGGGTAATCATCATTTTTATCGAATGAAGAGGGTTGGGAAATAGTTACATA
TAGGGAAGGGGGATCATTAA

Product: pyridine nucleotide-disulfide oxidoreductase; NADH dehydrogenase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKMFRDKYGIDAKVRHEVTKVDTEKKMVYA
EHTKTKDIFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVEL
GKKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLE
GTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRAFKGTLGTGIIKF
MNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNK
MSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Sequences:

>Translated_432_residues
MSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKMFRDKYGIDAKVRHEVTKVDTEKKMVYA
EHTKTKDIFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVEL
GKKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLE
GTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRAFKGTLGTGIIKF
MNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNK
MSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE
>Mature_431_residues
SAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKMFRDKYGIDAKVRHEVTKVDTEKKMVYAE
HTKTKDIFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELG
KKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLEG
TNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFM
NLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKM
SIHDLEDVDLSYAPPYNSVWDPIQQAARRAE

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=283, Percent_Identity=28.9752650176678, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI21389617, Length=283, Percent_Identity=28.9752650176678, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI65787454, Length=283, Percent_Identity=28.9752650176678, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1789065, Length=278, Percent_Identity=23.7410071942446, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082354, Length=318, Percent_Identity=25.1572327044025, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786307, Length=310, Percent_Identity=24.5161290322581, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789765, Length=340, Percent_Identity=22.9411764705882, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789915, Length=318, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32565766, Length=139, Percent_Identity=30.2158273381295, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24585130, Length=266, Percent_Identity=27.8195488721804, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI281359715, Length=266, Percent_Identity=25.5639097744361, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281359713, Length=266, Percent_Identity=25.5639097744361, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24639250, Length=266, Percent_Identity=25.5639097744361, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18543267, Length=266, Percent_Identity=25.5639097744361, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24639252, Length=266, Percent_Identity=25.5639097744361, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24639257, Length=266, Percent_Identity=25.5639097744361, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24581020, Length=269, Percent_Identity=26.3940520446097, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573993, Length=269, Percent_Identity=26.3940520446097, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358499, Length=215, Percent_Identity=32.093023255814, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 48371; Mature: 48240

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKMFRDKYGI
CCCHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHCCC
DAKVRHEVTKVDTEKKMVYAEHTKTKDIFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLL
CHHHHHHHHHCCCCHHEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEHH
KTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDAD
HHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCH
MAEYIHKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLE
HHHHHHHCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCC
GTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGL
CCCEEECCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECC
NMLDKRRAFKGTLGTGIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAK
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCC
PLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSV
CEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
WDPIQQAARRAE
HHHHHHHHHHCC
>Mature Secondary Structure 
SAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIARNVKMFRDKYGI
CCHHHHHCCCCCCCEEEEECCCEEEHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHCCC
DAKVRHEVTKVDTEKKMVYAEHTKTKDIFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLL
CHHHHHHHHHCCCCHHEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEHH
KTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDAD
HHCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCH
MAEYIHKEADKHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLE
HHHHHHHCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCC
GTNIRTNHKGAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGL
CCCEEECCCCEEEEEEEEECCCHHHEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECC
NMLDKRRAFKGTLGTGIIKFMNLTLARTGLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAK
CHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCC
PLYLKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSV
CEEEEEEECCCHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
WDPIQQAARRAE
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]