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The map label for this gene is trpE [H]

Identifier: 222094961

GI number: 222094961

Start: 1288892

End: 1290307

Strand: Direct

Name: trpE [H]

Synonym: BCQ_1299

Alternate gene names: 222094961

Gene position: 1288892-1290307 (Clockwise)

Preceding gene: 222094958

Following gene: 222094962

Centisome position: 24.72

GC content: 39.41

Gene sequence:

>1416_bases
ATGACGAAAGAAGAATTTATAAAACAAAAAAGAGAGAGAAAGACATTTTTAGTAATCGCTGAAGAAGAAGGAGATAGCAT
TACGCCAATTTCTTTATATAGACGTATGAAAGGGAAGAAGAAATTCTTATTAGAAAGTTCACAGCTTCATCAAGATAAAG
GGCGTTATTCTTACTTAGGATGTAATCCGTATGGGGAAGTGAAAAGCATTGGTACGGAAGTGGAACGAACGATTTACGGC
AGGGCAGAAAAGTTGCAAAGTAACGTACTTCAAGTGTTAGAAGAAGTGATCGCGTCAGCTCAAGTAGATAGTCCATTTCC
ATTTTGCGGTGGAGCAGTTGGTTATATTGGCTATGACGTCATTCGGCAATATGAAAACATTGGAGCAGATTTACATGATC
CATTGAATATTCCAGAAGTACACCTTTTACTATACCGTGAGTTTATCGTGTATGACCACTTACGCCAAAAGTTGTCGTTT
GTATATGTATGCAGGGAAGATGATTCAGCAGATTATGAAGAAGTATACGAAAGGCTGCAAGTATACAAAGAGGAAGTGCT
ACAGGGAGAAGAAGCGGAAGTAGCTGAAATAAGATCAACATTATCATTCACTTCTTCTATAACGGAAAGAGAATTTTGCG
TGATGGTAGAAACGGCGAAAGAACATATCGGGGCCGGGGACATATTTCAAGTTGTATTATCTCAGCGTTTGCAAAGCGAA
TGTATTGGAGATCCATTCGCGTTATATCGAAAACTTCGAATTGCCAATCCATCACCATATATGTTTTATATCGATTTTCA
AGATTATGTTGTACTCGGTTCTTCGCCAGAAAGTTTGTTATCGGTAAGGGAGGATAAAGTAATGACGAATCCAATTGCCG
GTACGAGACCGAGAGGGAAAACGAAGGAGGAAGATACGGAGATTGAAAAAGAACTGTTAGAAAATGAGAAAGAGCGAGCG
GAGCATATGATGCTTGTAGATCTAGGGCGAAATGATATTGGTAGAGTGAGTGAAATCGGCTCAGTTACGATAGATAAATA
TATGAAAGTAGAAAAATATTCTCACGTTATGCACATTGTATCTGAAGTTTACGGAACATTGCGAAAACGAATGAGCGGAT
TTGATGCATTAGCGTATTGCTTACCAGCGGGGACGGTATCAGGTGCTCCGAAAATTAGAGCGATGGAAATTATAAATGAG
CTAGAGAATGAAAAAAGAAATGTGTACGCCGGTGCAGTTGGATATGTTAGTTTTTCAGGAGATATTGATATGGCGCTCGC
CATTCGAACGATGGTCGTAAAGGATGAAAAAGCATACGTTCAGGCAGGAGCGGGCATCGTTTACGATTCAGATCCAGTAG
CTGAATATGAAGAAACATTAAATAAAGCGAGAGCGCTATTGGAGGTAATGAAATGA

Upstream 100 bases:

>100_bases
GCATCCAACACGAGGTGGTACCGCGGTATATTTATCGTCCTCTACATATTTTCGATATGTAGAGGACTTTTTTATTTTTC
AGGGCGAGGTGAAGGACATG

Downstream 100 bases:

>100_bases
TTGTACTGATCGATAATTATGATTCATTCACATATAACTTGTATCAACTATTAGGCGAATACGAAGAAGAGATTGTTGTC
GTAAGAAATGATCAAATAAC

Product: anthranilate synthase component i

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTKEEFIKQKRERKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLGCNPYGEVKSIGTEVERTIYG
RAEKLQSNVLQVLEEVIASAQVDSPFPFCGGAVGYIGYDVIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLRQKLSF
VYVCREDDSADYEEVYERLQVYKEEVLQGEEAEVAEIRSTLSFTSSITEREFCVMVETAKEHIGAGDIFQVVLSQRLQSE
CIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGKTKEEDTEIEKELLENEKERA
EHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIVSEVYGTLRKRMSGFDALAYCLPAGTVSGAPKIRAMEIINE
LENEKRNVYAGAVGYVSFSGDIDMALAIRTMVVKDEKAYVQAGAGIVYDSDPVAEYEETLNKARALLEVMK

Sequences:

>Translated_471_residues
MTKEEFIKQKRERKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLGCNPYGEVKSIGTEVERTIYG
RAEKLQSNVLQVLEEVIASAQVDSPFPFCGGAVGYIGYDVIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLRQKLSF
VYVCREDDSADYEEVYERLQVYKEEVLQGEEAEVAEIRSTLSFTSSITEREFCVMVETAKEHIGAGDIFQVVLSQRLQSE
CIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGKTKEEDTEIEKELLENEKERA
EHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIVSEVYGTLRKRMSGFDALAYCLPAGTVSGAPKIRAMEIINE
LENEKRNVYAGAVGYVSFSGDIDMALAIRTMVVKDEKAYVQAGAGIVYDSDPVAEYEETLNKARALLEVMK
>Mature_470_residues
TKEEFIKQKRERKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLGCNPYGEVKSIGTEVERTIYGR
AEKLQSNVLQVLEEVIASAQVDSPFPFCGGAVGYIGYDVIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLRQKLSFV
YVCREDDSADYEEVYERLQVYKEEVLQGEEAEVAEIRSTLSFTSSITEREFCVMVETAKEHIGAGDIFQVVLSQRLQSEC
IGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGKTKEEDTEIEKELLENEKERAE
HMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIVSEVYGTLRKRMSGFDALAYCLPAGTVSGAPKIRAMEIINEL
ENEKRNVYAGAVGYVSFSGDIDMALAIRTMVVKDEKAYVQAGAGIVYDSDPVAEYEETLNKARALLEVMK

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=436, Percent_Identity=30.9633027522936, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1787518, Length=365, Percent_Identity=36.7123287671233, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1786809, Length=292, Percent_Identity=26.7123287671233, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082077, Length=313, Percent_Identity=26.517571884984, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320935, Length=441, Percent_Identity=41.2698412698413, Blast_Score=326, Evalue=5e-90,
Organism=Saccharomyces cerevisiae, GI6324361, Length=407, Percent_Identity=25.5528255528256, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 53549; Mature: 53417

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEEFIKQKRERKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLG
CCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEC
CNPYGEVKSIGTEVERTIYGRAEKLQSNVLQVLEEVIASAQVDSPFPFCGGAVGYIGYDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
IRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLRQKLSFVYVCREDDSADYEEVYERLQ
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHH
VYKEEVLQGEEAEVAEIRSTLSFTSSITEREFCVMVETAKEHIGAGDIFQVVLSQRLQSE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHEEEHHHHHHCCCHHHHHHHHHHHHHHH
CIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGK
HCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
TKEEDTEIEKELLENEKERAEHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIV
CCCHHHHHHHHHHHCHHHHHHHEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
SEVYGTLRKRMSGFDALAYCLPAGTVSGAPKIRAMEIINELENEKRNVYAGAVGYVSFSG
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEEEECC
DIDMALAIRTMVVKDEKAYVQAGAGIVYDSDPVAEYEETLNKARALLEVMK
CCHHHHHHHHHHHCCCHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TKEEFIKQKRERKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLG
CHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEC
CNPYGEVKSIGTEVERTIYGRAEKLQSNVLQVLEEVIASAQVDSPFPFCGGAVGYIGYDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
IRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLRQKLSFVYVCREDDSADYEEVYERLQ
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHH
VYKEEVLQGEEAEVAEIRSTLSFTSSITEREFCVMVETAKEHIGAGDIFQVVLSQRLQSE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHEEEHHHHHHCCCHHHHHHHHHHHHHHH
CIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGK
HCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
TKEEDTEIEKELLENEKERAEHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIV
CCCHHHHHHHHHHHCHHHHHHHEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
SEVYGTLRKRMSGFDALAYCLPAGTVSGAPKIRAMEIINELENEKRNVYAGAVGYVSFSG
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEEEECC
DIDMALAIRTMVVKDEKAYVQAGAGIVYDSDPVAEYEETLNKARALLEVMK
CCHHHHHHHHHHHCCCHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2732211 [H]