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The map label for this gene is mecA

Identifier: 222094919

GI number: 222094919

Start: 1250885

End: 1251538

Strand: Direct

Name: mecA

Synonym: BCQ_1257

Alternate gene names: 222094919

Gene position: 1250885-1251538 (Clockwise)

Preceding gene: 222094917

Following gene: 222094920

Centisome position: 23.99

GC content: 35.63

Gene sequence:

>654_bases
ATGAAATTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCGTGAGGAAATTTGGTATGACCGCGAAAGAAG
CGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATTTCTTTATTGATGGGCCGTTATGGATTCAAG
TGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTTTCAAAGGATGGACAAAAGCTAGAACTACCA
ATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGTATTGAATCATTATTCCAGCAAGAATTAGTGGAAGAGGT
AGAGGAACAAGCAGGTACAAACTTTAACGAAGATGGTACGTTTGGCTTTTTAATTAAGTTTAATGATTTTGAAGATGTCA
TTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTATTCATTTGAGGACCGCTATTATGTATATGTG
GAATTCGATGAAGTGCTACATGATGAAGAAGAAATTGATCGCATTTTAAGCATTGTTTTAGAATACGGGGAAGAATCAAC
TTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGCATGCGCTTGAAACAATTCGCAATAATTTTC
CTGCTAAAACGTAG

Upstream 100 bases:

>100_bases
ATCTATTGATTTGTCATATGAGTGGGGAATCCCTTCATAACAATTCTAAGCAGGAAGGGAGAGTTGTATTTTGGATATTG
AAAGAATTAATGATCATACG

Downstream 100 bases:

>100_bases
GCCGATTTCTGTAGTATGAAATCGGCTTTTTATATGAAGAATAGGAAAGCTTTCTTAGTAAGGAGGTAAGAGATGAAAAA
TACGTTAAAGTTGATTTTCT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAELSKDGQKLELP
IGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYV
EFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Sequences:

>Translated_217_residues
MKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAELSKDGQKLELP
IGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYV
EFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
>Mature_217_residues
MKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAELSKDGQKLELP
IGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYV
EFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MECA1_BACAN (Q81TR3)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_843678.2
- RefSeq:   YP_017815.1
- RefSeq:   YP_027383.1
- EnsemblBacteria:   EBBACT00000011119
- EnsemblBacteria:   EBBACT00000015190
- EnsemblBacteria:   EBBACT00000023423
- GeneID:   1089261
- GeneID:   2819275
- GeneID:   2849130
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_1203
- KEGG:   bar:GBAA_1203
- KEGG:   bat:BAS1111
- TIGR:   BA_1203
- TIGR:   GBAA_1203
- GeneTree:   EBGT00050000001420
- HOGENOM:   HBG491202
- OMA:   VFVTKSD
- ProtClustDB:   PRK02315
- BioCyc:   BANT260799:BAS1111-MONOMER
- BioCyc:   BANT261594:GBAA1203-MONOMER
- HAMAP:   MF_01124
- InterPro:   IPR008681
- PIRSF:   PIRSF029008

Pfam domain/function: PF05389 MecA

EC number: NA

Molecular weight: Translated: 25741; Mature: 25741

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKG
CEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEECCC
IEVLVTKAELSKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGT
EEEEEEHHHHCCCCCEEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYVEFDEVLHDEEEIDRILSIVL
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHHHHHHHHHHHH
EYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKG
CEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEECCC
IEVLVTKAELSKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGT
EEEEEEHHHHCCCCCEEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FGFLIKFNDFEDVISLSHRLIFEDIKDELYSFEDRYYVYVEFDEVLHDEEEIDRILSIVL
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHHHHHHHHHHHH
EYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629