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The map label for this gene is comK [H]

Identifier: 222094858

GI number: 222094858

Start: 1185291

End: 1185872

Strand: Direct

Name: comK [H]

Synonym: BCQ_1196

Alternate gene names: 222094858

Gene position: 1185291-1185872 (Clockwise)

Preceding gene: 222094856

Following gene: 222094859

Centisome position: 22.73

GC content: 34.54

Gene sequence:

>582_bases
ATGGAAAGTAAAGTAGAACGCTACGTCGAAAACTATGTTGTAAATAAAAATACAATGGCCTTACTTCCTGTAATTCTCAG
TGAAAAGAAAATTGTTACGCGAGTTGTTGAAGTGCAAGACTCTTTTTTCGTATTTCAAAAACCTCTAGATATTATAGAAA
GAAGTTGTCGCAAGCATGGTTCTAGTTTCTTAGGCAGAAAAGAAGGAACGAAAGAGTTAACTCACATTACACATAAAGCA
CCAATTGCAATTAGTCCGACCGATCAACTTTATTTTTTCCCTACCTATTCGTATTCTAGAAAAGAGTGCGCGTGGTTATC
TCATTTTTATATTGAAAGCAATAAAGAATTAAAAGATGGAAACCTTATTATCCGATTTATAAATGGTTTTGCTGTGAAGT
TAGAGATATCGAAAACTAGTTTTGAAAATCAACAAAATCGTACTGCGAAATTGCGAACGGAGTATGAAGATCGTAGGAAA
AAACAAGGGAATCCTTGCTTTAAAGAGGTTGATCAAAGGGATGAATCAACATTAAGACCAGCTTATGAGAGAGTGTATGT
TGTTAGAGAAGAGGATGTGTGA

Upstream 100 bases:

>100_bases
TATTGTAAAAAAGCGGAATCTGTAAGCCATTTCCTTTTCATAGATGCTAAAATTATACATGCAGCTGCTAATATAAATAG
AAAAAAGGAGATAGTGGAAT

Downstream 100 bases:

>100_bases
GAGGAAAAGGATGAGGTGACTCATCCTTTTTGATTTCATTATATATACAGTTTACGTTGTAAGATTTATAAACAAAATGA
GAGAATGTAAAAACTTTTGT

Product: competence transcription factor

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MESKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDQRDESTLRPAYERVYVVREEDV

Sequences:

>Translated_193_residues
MESKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDQRDESTLRPAYERVYVVREEDV
>Mature_193_residues
MESKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHGSSFLGRKEGTKELTHITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDGNLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRK
KQGNPCFKEVDQRDESTLRPAYERVYVVREEDV

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 22755; Mature: 22755

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHG
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
SSFLGRKEGTKELTHITHKAPIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDG
HHHHCCCCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHHHHHHEEECCCCCCCCC
NLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRKKQGNPCFKEVDQRDESTLRP
CEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCH
AYERVYVVREEDV
HHHEEEEEEECCC
>Mature Secondary Structure
MESKVERYVENYVVNKNTMALLPVILSEKKIVTRVVEVQDSFFVFQKPLDIIERSCRKHG
CCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
SSFLGRKEGTKELTHITHKAPIAISPTDQLYFFPTYSYSRKECAWLSHFYIESNKELKDG
HHHHCCCCCHHHHHHHHCCCCEEECCCCCEEEEECCCCCCHHHHHHHHEEECCCCCCCCC
NLIIRFINGFAVKLEISKTSFENQQNRTAKLRTEYEDRRKKQGNPCFKEVDQRDESTLRP
CEEEEEECCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCH
AYERVYVVREEDV
HHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]