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The map label for this gene is aceB [H]

Identifier: 222094853

GI number: 222094853

Start: 1179689

End: 1181278

Strand: Direct

Name: aceB [H]

Synonym: BCQ_1191

Alternate gene names: 222094853

Gene position: 1179689-1181278 (Clockwise)

Preceding gene: 222094852

Following gene: 222094854

Centisome position: 22.62

GC content: 38.74

Gene sequence:

>1590_bases
ATGTCGACGCAAACTTCACGGGTTACATTGCCCGGAGAAATGTTGCCAGCGTACAACGAAATATTGACACCTGAGGCGCT
TAGTTTTTTGAAGGAACTACATGGAAATTTCAATGAGCGCCGCATAGAACTTTTACAAAAGCGTGCGGAGAAACAAAAGA
GAATTGATGCAGGGGAGTTTCCGAAGTTTTTAGAAGAAACGAAGCACATACGTGAAGCTGATTGGACAATTGCTAAATTG
CCAAAAGATTTAGAGGATCGCCGCGTAGAGATTACTGGCCCGGTAGATAGAAAGATGGTTATTAACGCTTTAAATTCAGG
AGCACATCTTTTTATGGCGGATTTTGAAGATTCGAATTCACCAACTTGGGAAAATGCGATTGAAGGTCAAATAAACTTAC
GAGATGCAGTAAAGGGAACGATTTCACATAAAAATGAAAACGGAAAAGAATATCATTTAAATAGTAAAACAGCAGTATTA
ATTGTGCGTCCAAGAGGATGGCATTTAGAAGAAAAACATATGCAAGTTGACGGAAAGAATATGTCTGGTAGCTTAGTAGA
TTTTGGACTTTATTTTTTCCATAATGCGAAAGCTCTTTTAGCAAAAGGAAGCGGTCCATACTTTTACTTACCGAAAATGG
AAAGCCATTTAGAAGCAAGGTTATGGAATGATGTTTTCGTATTTGCTCAAAAATATATCGGTATTCCAAACGGAACGATC
AAAGCCACGGTGTTACTGGAAACGATACATGCTTCGTTTGAAATGGATGAAATTTTGTATGAGCTTAAAGATCATTCTGC
TGGATTAAATTGCGGAAGATGGGATTATATTTTTAGTTTTCTAAAGGGTTTCCGTAATCATAATCAATTTTTACTTCCAG
ATAGAGCGCAAGTCACGATGACGGCGCCATTTATGCGCGCGTATTCTTTGAAAGTCATTCAAACATGTCACCGTCGTAAT
GCACCAGCTATTGGAGGAATGGCAGCACAAATTCCAATTAAAAACAATCCAGAAGCAAATGAAGCAGCTTTTGAAAAAGT
TCGTGCGGATAAGGAGCGCGAAGCTTTAGACGGTCATGACGGGACTTGGGTTGCCCACCCGGGACTTGTACCAGTCGCGA
TGGAAGTATTTAATCACATTATGAAAACGCCGAATCAAATTTTTAGAAAACGTGAAGAAATACATGTTACAGAAAAGGAT
TTATTAGAAGTACCAGTGGGAACGATTACAGAAGAGGGTCTTCGTCTGAATATTAGCGTAGGTATTCAATATATTGCATC
TTGGTTAAGCGGCCGAGGAGCAGCACCAATTTATAACTTAATGGAAGATGCAGCAACAGCGGAAATTTCTAGGGCACAAG
TATGGCAATGGATTCGCCATGAAGGTGGAAAATTAAATGATGGCCGTAATATTACACTTGAATTAATGGAAGAGCTAAAA
GAAGAAGAGTTAGCAAAAATAGAAAGAGAGATTGGTAAAGAAGCCTTTAAGGAAGGGAGATTCCAAGAGGCGACAACGTT
GTTTACAAATCTCGTTCGGAATGATGAATTCGTACCATTTTTAACATTACCGGGTTATGAAATTTTATAA

Upstream 100 bases:

>100_bases
TAAATTTTCAAAAAAAAACTTCCTTTTCTGAAGATTTGTTATATAATATAAAACATAAAATCAAATCTGTTATAAAACAG
TTTAAGAAGGGGATGCTAAT

Downstream 100 bases:

>100_bases
AAAGTGAAAAGGGGATGGAACAAATGAAAAACGAAAGAATCGAGAAATTACAAGAGAGCTGGGAACTAGATACGCGTTGG
AAAGGGATCACACGTCCATA

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSTQTSRVTLPGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEFPKFLEETKHIREADWTIAKL
PKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAIEGQINLRDAVKGTISHKNENGKEYHLNSKTAVL
IVRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESHLEARLWNDVFVFAQKYIGIPNGTI
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKGFRNHNQFLLPDRAQVTMTAPFMRAYSLKVIQTCHRRN
APAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKD
LLEVPVGTITEEGLRLNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
EEELAKIEREIGKEAFKEGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL

Sequences:

>Translated_529_residues
MSTQTSRVTLPGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEFPKFLEETKHIREADWTIAKL
PKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAIEGQINLRDAVKGTISHKNENGKEYHLNSKTAVL
IVRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESHLEARLWNDVFVFAQKYIGIPNGTI
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKGFRNHNQFLLPDRAQVTMTAPFMRAYSLKVIQTCHRRN
APAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKD
LLEVPVGTITEEGLRLNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
EEELAKIEREIGKEAFKEGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
>Mature_528_residues
STQTSRVTLPGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEFPKFLEETKHIREADWTIAKLP
KDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAIEGQINLRDAVKGTISHKNENGKEYHLNSKTAVLI
VRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESHLEARLWNDVFVFAQKYIGIPNGTIK
ATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKGFRNHNQFLLPDRAQVTMTAPFMRAYSLKVIQTCHRRNA
PAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKDL
LEVPVGTITEEGLRLNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELKE
EELAKIEREIGKEAFKEGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=512, Percent_Identity=55.2734375, Blast_Score=568, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17561814, Length=525, Percent_Identity=56.1904761904762, Blast_Score=589, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI71982926, Length=418, Percent_Identity=59.0909090909091, Blast_Score=505, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6324212, Length=515, Percent_Identity=51.4563106796116, Blast_Score=526, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6322222, Length=516, Percent_Identity=50.7751937984496, Blast_Score=516, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 60310; Mature: 60178

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQTSRVTLPGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEF
CCCCCCEEECCHHHCCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
PKFLEETKHIREADWTIAKLPKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNS
HHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCC
PTWENAIEGQINLRDAVKGTISHKNENGKEYHLNSKTAVLIVRPRGWHLEEKHMQVDGKN
CCCHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHEECCCC
MSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESHLEARLWNDVFVFAQKYIGIPNGTI
CCCCHHHHHHHHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKGFRNHNQFLLPDRAQVTM
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCEEEE
TAPFMRAYSLKVIQTCHRRNAPAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHD
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCC
GTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKDLLEVPVGTITEEGLRLNISV
CCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEEHH
GIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
EEELAKIEREIGKEAFKEGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
STQTSRVTLPGEMLPAYNEILTPEALSFLKELHGNFNERRIELLQKRAEKQKRIDAGEF
CCCCCEEECCHHHCCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
PKFLEETKHIREADWTIAKLPKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNS
HHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCC
PTWENAIEGQINLRDAVKGTISHKNENGKEYHLNSKTAVLIVRPRGWHLEEKHMQVDGKN
CCCHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHEECCCC
MSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESHLEARLWNDVFVFAQKYIGIPNGTI
CCCCHHHHHHHHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKGFRNHNQFLLPDRAQVTM
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCEEEE
TAPFMRAYSLKVIQTCHRRNAPAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHD
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCC
GTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEIHVTEKDLLEVPVGTITEEGLRLNISV
CCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEEHH
GIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
EEELAKIEREIGKEAFKEGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA