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The map label for this gene is yhfN [H]

Identifier: 222094848

GI number: 222094848

Start: 1174358

End: 1175674

Strand: Direct

Name: yhfN [H]

Synonym: BCQ_1186

Alternate gene names: 222094848

Gene position: 1174358-1175674 (Clockwise)

Preceding gene: 222094847

Following gene: 222094849

Centisome position: 22.52

GC content: 37.05

Gene sequence:

>1317_bases
ATGTACGAACTTACAATAATAATAGACAGGCAGCATAGAGGAGGGAATAGCGTGAGGAAGGTTATCGGGTGGTCGCTTTT
TTTGTACGTTGGGTTTGCGTTATTTATATATTGGTATTTACTTGGATGGAATCATGAACTAATTCCTGACATGTACAAAG
GAACGAGTGCAGATCCAGAAACGTTTATGAATGCAAGAGAGCTTACGCTAAGCCAAGATTATTCGCGCGTGAAAAATTTA
CTGTATTTTTTAGCGACGCCTCTTGAATGGATTATTTTATTATTTGTACTTGTGCTCGGTATTTCAAAAAAGTTTGAGAA
ATGGTCGAAGGAAACGACGAAAATAAGTGTCCTGCAAGTTGCGATTTATTTCTTTTATTTATCATTACTTACAACAGTTC
TTGCCCTGCCAATGCAATGGATTAGCCGAAAAGTGTCCGTTGATTACGGCATTTCAACGCAAAGTACACAAAGCTGGATA
AAAGATCATGTTATCGGTTTTTGGGAGAGCTATGCGACTATGTTAATTGTAGTTACGGTTCTTCTATGGCTTATCCGTAA
ATTCCCGAAGAGATGGTGGTTAGCAGGGTGGGCGCTCTCTGTTCCGTTTACAATCTTTTTAACATTTATACAACCTGTTG
TGATTGATCCGCTATATAACGATTTCTCGACGCTGAAAAATAAAGAGTTAGAAACGAAAATTTTAGCGATGGCAGATAAA
GCTGACATTCCGGCAAAACACGTATATGAAGTAAATATGTCGGAAAAAACGAATGCGTTAAATGCTTACGTAACAGGAAT
TGGGCCTAATGCCCGAATTGTAATGTGGGATACAACGCTTAAGCAATTAAAAGATAAAGAGATTTTATTTATAATGGCCC
ATGAAATGGGGCATTATGTTATGAAACATATATATTGGGGCGTTGCGAGTTATGTGTTGCTATCGTTTATAGGGATGTAC
CTCATTAGTCGTATTATAAATATGTGTATTCGAAAATGGGGGGATACGCTGCAAATTTCAAAAGCAGCATGTTTCTCAAT
TTTACCTTTATTTTTCTTAATTTCTTCTGTCCTCTCTTTTGTATCACAACCAGCAACAAACTATGTTTCTCGTATAGAAG
AACGAGCGGCAGACCAATATGCTTTAGACATGACGAAGGACGGGAAATCTGGTGTAAAAACGTTTCAATATTTATCAAAA
ACGAGTTTAAGCCAAGTAAATCCTCCTGCGTTAGTGAAGTTTTTCTTATACACACATCCACCAATTTTCGAAAGAATTCA
TACATTTGAACAATATGAAAAGGAAAAGAAGCGGTAG

Upstream 100 bases:

>100_bases
CGTCTAAAGGTAGGTAAAACTCTTCTATTTGTAGAAGAGTTTTTTTATGTAAATAAAAGGATCTCGAGCAATTCGCGTAA
TAAGCTTGTTCTAATTTAGC

Downstream 100 bases:

>100_bases
TGTACTGCTTCTTTTTTTATGCGTTATTCGAGTTTTGGAAAATTATAGTGTATAATATATGGAATATTCAGTGAAATGTT
TAGGAGGTTAATATTTTGTT

Product: metalloprotease

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLLGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNL
LYFLATPLEWIILLFVLVLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWI
KDHVIGFWESYATMLIVVTVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAMADK
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYVLLSFIGMY
LISRIINMCIRKWGDTLQISKAACFSILPLFFLISSVLSFVSQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSK
TSLSQVNPPALVKFFLYTHPPIFERIHTFEQYEKEKKR

Sequences:

>Translated_438_residues
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLLGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNL
LYFLATPLEWIILLFVLVLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWI
KDHVIGFWESYATMLIVVTVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAMADK
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYVLLSFIGMY
LISRIINMCIRKWGDTLQISKAACFSILPLFFLISSVLSFVSQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSK
TSLSQVNPPALVKFFLYTHPPIFERIHTFEQYEKEKKR
>Mature_438_residues
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLLGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNL
LYFLATPLEWIILLFVLVLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWI
KDHVIGFWESYATMLIVVTVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAMADK
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYVLLSFIGMY
LISRIINMCIRKWGDTLQISKAACFSILPLFFLISSVLSFVSQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSK
TSLSQVNPPALVKFFLYTHPPIFERIHTFEQYEKEKKR

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=425, Percent_Identity=22.1176470588235, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17505484, Length=438, Percent_Identity=21.0045662100457, Blast_Score=86, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322577, Length=323, Percent_Identity=26.625386996904, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19922414, Length=403, Percent_Identity=19.3548387096774, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 50933; Mature: 50933

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00142 ZINC_PROTEASE ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLLGWNHELIPDMYKGTSADPE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCHH
TFMNARELTLSQDYSRVKNLLYFLATPLEWIILLFVLVLGISKKFEKWSKETTKISVLQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIVVTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAMADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYV
CCCCHHHEEEECCCCCCCCHHEEEEEECCCCEEEEECCHHHHCCCCCEEEEEHHHHHHHH
MKHIYWGVASYVLLSFIGMYLISRIINMCIRKWGDTLQISKAACFSILPLFFLISSVLSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLYTHP
HHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PIFERIHTFEQYEKEKKR
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYELTIIIDRQHRGGNSVRKVIGWSLFLYVGFALFIYWYLLGWNHELIPDMYKGTSADPE
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCHH
TFMNARELTLSQDYSRVKNLLYFLATPLEWIILLFVLVLGISKKFEKWSKETTKISVLQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIVVTV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAMADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
ADIPAKHVYEVNMSEKTNALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYV
CCCCHHHEEEECCCCCCCCHHEEEEEECCCCEEEEECCHHHHCCCCCEEEEEHHHHHHHH
MKHIYWGVASYVLLSFIGMYLISRIINMCIRKWGDTLQISKAACFSILPLFFLISSVLSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VSQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLYTHP
HHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PIFERIHTFEQYEKEKKR
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]