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The map label for this gene is secA-1 [H]

Identifier: 222094632

GI number: 222094632

Start: 954139

End: 956505

Strand: Reverse

Name: secA-1 [H]

Synonym: BCQ_0970

Alternate gene names: 222094632

Gene position: 956505-954139 (Counterclockwise)

Preceding gene: 222094637

Following gene: 222094631

Centisome position: 18.34

GC content: 35.78

Gene sequence:

>2367_bases
ATGCTGAATTCGGTAAAAAAGCTGTTAGGAGATTCTCAGAAGAGAAAACTAAAAAAGTATGAACAACTTGTTCAAGAAAT
TAATAATCTGGAAGAAAAACTATCTGATTTATCTGATGAAGAATTGCGTCATAAAACAATCACATTTAAAAACATGCTTC
GTGACGGAAAAACAGTGGATGATATAAAAGTTGAAGCGTTCGCTGTTGTACGTGAAGCAGCAAAACGTGTACTTGGATTA
CGTCACTACGATGTACAGTTAATTGGTGGCCTTGTACTATTAGAAGGTAATATTGCAGAGATGCCAACTGGTGAAGGAAA
AACATTAGTTTCTTCTCTTCCAACATACGTACGTGCTCTTGAAGGAAAAGGCGTTCACGTTATTACTGTAAACGACTATT
TAGCAAAACGAGATAAAGAATTAATTGGCCAAGTTCATGAATTTCTAGGTTTAAAGGTTGGATTAAATATTCCTCAAATC
GATCCTGCCGAAAAGAAACTTGCTTACGAAGCTGATATTACATACGGTATTGGAACAGAATTTGGCTTTGACTATCTACG
TGATAATATGGCTGCTTCAAAAGATGAGCAGGTGCAACGTCCTTATCATTTTGCTATTATCGATGAGATTGATAGCGTTT
TAATTGATGAAGCGAAGACGCCTCTTATTATCGCCGGTAAAAAATCAAGCAGCTCTGATTTACACTATTTATGTGCAAAA
GTTATTAAATCATTCCAAGATACTCTTCATTACACATACGATGCAGAAACGAAATCTGCTAGTTTTACAGAAGACGGTAT
TACAAAAATAGAAGATTTATTTGATATCGATAACCTATATGATTTAGAGCATCAAACTTTATATCATTATATGATTCAAG
CATTACGAGCTCATGTCGCTTTCCAATGTGATGTTGACTATATTGTACACGATGAAAAAATTCTACTTGTAGATATTTTC
ACGGGCCGCGTTATGGATGGTCGCTCTTTAAGTGACGGTTTACACCAAGCTCTTGAAGCAAAAGAAGGCTTAGAAATCAC
TGAAGAAAATCAAACACAAGCATCCATTACAATTCAAAACTTCTTCCGTATGTATCCAGCACTATCTGGTATGACAGGTA
CAGCAAAAACGGAAGAAAAAGAATTTAACCGTGTATATAACATGGAAGTTATGCCGATTCCGACAAATCGTCCAATCATT
CGTGAAGACAAAAAAGACGTCGTATACGTAACAGCCGATGCAAAATATAAAGCTGTACGTGAAGATGTTCTAAAGCACAA
TAAACAAGGACGCCCGATTTTAATTGGGACAATGTCTATTTTACAATCAGAAACCGTTGCCCGTTACTTAGATGAAGCAA
ATATTACATATCAATTATTAAATGCAAAAAGCGCAGAACAAGAAGCTGATTTAATCGCAACTGCTGGACAAAAAGGTCAA
ATTACAATTGCGACGAATATGGCCGGACGAGGTACTGATATTTTACTAGGTGAGGGTGTTCACGAACTTGGTGGATTACA
TGTAATCGGGACAGAACGCCATGAATCGCGACGCGTTGACAATCAGCTAAAAGGTCGTGCTGGTCGCCAAGGTGACCCAG
GTAGCTCTCAATTCTTCCTTTCTTTAGAAGATGAAATGCTAAAACGTTTCGCACAAGAAGAAGTCGAGAAATTAATGAAA
TCACTGAAAACAGATGAAACAGGACTTATTCTAACTTCTAAAGTCCATGATTTTGTAAACCGTACACAATTAATTTGTGA
AGGTAGCCATTTCTCCATGCGTGAGTACAATTTAAAGTTAGACGATGTAATAAATGACCAACGTAACGTTATTTATAAAT
TACGTAATAACTTATTACAAGAAGATACAAATATGATTGAAATTATTATTCCAATGATTGATCATGCTGTAGAAGCCATT
TCTAAGCAATATCTTGTAGAAGGTATGCTTCCAGAAGAATGGGATTTTGCTAGTTTAACAGCAAGTCTAAACGAAATTTT
ATCAGTAGAAAATATGCCATCATTATCAGCAAATAATGTACATTCACCGGAAGATTTACAATCCGTTTTGAAAGAAACAT
TATCTCTTTATAAAGAGCGCGTAAATGAGCTAGATAGCCATACTGATTTACAACAGTCGCTACGATATGTTGCCCTTCAT
TTCCTAGATCAAAACTGGGTCAATCACTTAGATGCAATGACTCACTTAAAAGAAGGCATCGGACTAAGACAATATCAACA
AGAAGACCCTACTCGTCTTTATCAAAAAGAAGCTTTAGATATCTTTTTATACACATATGGTAATTTCGAAAAAGAAATGT
GCCGCTATGTTGCAAGACATTTAGGTGTTCCTGAAAACGTACAATAA

Upstream 100 bases:

>100_bases
TTATTTATATCCAGTTATTTCTTCAATTTACTACTTCTACTTATTCGGGATAAACATGTGCTATAATGTAGCTATTGTCA
GTAAGAGGAGTGTTTACAAC

Downstream 100 bases:

>100_bases
CGAGGTGAAAGATTATGTTATCATTCCTAAAAAAAGCGAAGAAAAACGGAAAAGATACGACTGTCTCTAGTAATCAACTA
TTCGGACAAGAAAGCACAAA

Product: preprotein translocase subunit seca

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MLNSVKKLLGDSQKRKLKKYEQLVQEINNLEEKLSDLSDEELRHKTITFKNMLRDGKTVDDIKVEAFAVVREAAKRVLGL
RHYDVQLIGGLVLLEGNIAEMPTGEGKTLVSSLPTYVRALEGKGVHVITVNDYLAKRDKELIGQVHEFLGLKVGLNIPQI
DPAEKKLAYEADITYGIGTEFGFDYLRDNMAASKDEQVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKKSSSSDLHYLCAK
VIKSFQDTLHYTYDAETKSASFTEDGITKIEDLFDIDNLYDLEHQTLYHYMIQALRAHVAFQCDVDYIVHDEKILLVDIF
TGRVMDGRSLSDGLHQALEAKEGLEITEENQTQASITIQNFFRMYPALSGMTGTAKTEEKEFNRVYNMEVMPIPTNRPII
REDKKDVVYVTADAKYKAVREDVLKHNKQGRPILIGTMSILQSETVARYLDEANITYQLLNAKSAEQEADLIATAGQKGQ
ITIATNMAGRGTDILLGEGVHELGGLHVIGTERHESRRVDNQLKGRAGRQGDPGSSQFFLSLEDEMLKRFAQEEVEKLMK
SLKTDETGLILTSKVHDFVNRTQLICEGSHFSMREYNLKLDDVINDQRNVIYKLRNNLLQEDTNMIEIIIPMIDHAVEAI
SKQYLVEGMLPEEWDFASLTASLNEILSVENMPSLSANNVHSPEDLQSVLKETLSLYKERVNELDSHTDLQQSLRYVALH
FLDQNWVNHLDAMTHLKEGIGLRQYQQEDPTRLYQKEALDIFLYTYGNFEKEMCRYVARHLGVPENVQ

Sequences:

>Translated_788_residues
MLNSVKKLLGDSQKRKLKKYEQLVQEINNLEEKLSDLSDEELRHKTITFKNMLRDGKTVDDIKVEAFAVVREAAKRVLGL
RHYDVQLIGGLVLLEGNIAEMPTGEGKTLVSSLPTYVRALEGKGVHVITVNDYLAKRDKELIGQVHEFLGLKVGLNIPQI
DPAEKKLAYEADITYGIGTEFGFDYLRDNMAASKDEQVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKKSSSSDLHYLCAK
VIKSFQDTLHYTYDAETKSASFTEDGITKIEDLFDIDNLYDLEHQTLYHYMIQALRAHVAFQCDVDYIVHDEKILLVDIF
TGRVMDGRSLSDGLHQALEAKEGLEITEENQTQASITIQNFFRMYPALSGMTGTAKTEEKEFNRVYNMEVMPIPTNRPII
REDKKDVVYVTADAKYKAVREDVLKHNKQGRPILIGTMSILQSETVARYLDEANITYQLLNAKSAEQEADLIATAGQKGQ
ITIATNMAGRGTDILLGEGVHELGGLHVIGTERHESRRVDNQLKGRAGRQGDPGSSQFFLSLEDEMLKRFAQEEVEKLMK
SLKTDETGLILTSKVHDFVNRTQLICEGSHFSMREYNLKLDDVINDQRNVIYKLRNNLLQEDTNMIEIIIPMIDHAVEAI
SKQYLVEGMLPEEWDFASLTASLNEILSVENMPSLSANNVHSPEDLQSVLKETLSLYKERVNELDSHTDLQQSLRYVALH
FLDQNWVNHLDAMTHLKEGIGLRQYQQEDPTRLYQKEALDIFLYTYGNFEKEMCRYVARHLGVPENVQ
>Mature_788_residues
MLNSVKKLLGDSQKRKLKKYEQLVQEINNLEEKLSDLSDEELRHKTITFKNMLRDGKTVDDIKVEAFAVVREAAKRVLGL
RHYDVQLIGGLVLLEGNIAEMPTGEGKTLVSSLPTYVRALEGKGVHVITVNDYLAKRDKELIGQVHEFLGLKVGLNIPQI
DPAEKKLAYEADITYGIGTEFGFDYLRDNMAASKDEQVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKKSSSSDLHYLCAK
VIKSFQDTLHYTYDAETKSASFTEDGITKIEDLFDIDNLYDLEHQTLYHYMIQALRAHVAFQCDVDYIVHDEKILLVDIF
TGRVMDGRSLSDGLHQALEAKEGLEITEENQTQASITIQNFFRMYPALSGMTGTAKTEEKEFNRVYNMEVMPIPTNRPII
REDKKDVVYVTADAKYKAVREDVLKHNKQGRPILIGTMSILQSETVARYLDEANITYQLLNAKSAEQEADLIATAGQKGQ
ITIATNMAGRGTDILLGEGVHELGGLHVIGTERHESRRVDNQLKGRAGRQGDPGSSQFFLSLEDEMLKRFAQEEVEKLMK
SLKTDETGLILTSKVHDFVNRTQLICEGSHFSMREYNLKLDDVINDQRNVIYKLRNNLLQEDTNMIEIIIPMIDHAVEAI
SKQYLVEGMLPEEWDFASLTASLNEILSVENMPSLSANNVHSPEDLQSVLKETLSLYKERVNELDSHTDLQQSLRYVALH
FLDQNWVNHLDAMTHLKEGIGLRQYQQEDPTRLYQKEALDIFLYTYGNFEKEMCRYVARHLGVPENVQ

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=840, Percent_Identity=42.5, Blast_Score=655, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 89589; Mature: 89589

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSVKKLLGDSQKRKLKKYEQLVQEINNLEEKLSDLSDEELRHKTITFKNMLRDGKTVD
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
DIKVEAFAVVREAAKRVLGLRHYDVQLIGGLVLLEGNIAEMPTGEGKTLVSSLPTYVRAL
HHHHHHHHHHHHHHHHHHCCCCCCHHEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
EGKGVHVITVNDYLAKRDKELIGQVHEFLGLKVGLNIPQIDPAEKKLAYEADITYGIGTE
CCCCEEEEEECHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHEEEECCCEECCCCH
FGFDYLRDNMAASKDEQVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKKSSSSDLHYLCAK
HHHHHHHHHHCCCCCHHHCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
VIKSFQDTLHYTYDAETKSASFTEDGITKIEDLFDIDNLYDLEHQTLYHYMIQALRAHVA
HHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHEE
FQCDVDYIVHDEKILLVDIFTGRVMDGRSLSDGLHQALEAKEGLEITEENQTQASITIQN
EEECCCEEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHEEEHHH
FFRMYPALSGMTGTAKTEEKEFNRVYNMEVMPIPTNRPIIREDKKDVVYVTADAKYKAVR
HHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEECCCHHHHHH
EDVLKHNKQGRPILIGTMSILQSETVARYLDEANITYQLLNAKSAEQEADLIATAGQKGQ
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCE
ITIATNMAGRGTDILLGEGVHELGGLHVIGTERHESRRVDNQLKGRAGRQGDPGSSQFFL
EEEEECCCCCCCEEEECCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
SLEDEMLKRFAQEEVEKLMKSLKTDETGLILTSKVHDFVNRTQLICEGSHFSMREYNLKL
ECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHEEECCCCCCHHHCCCCH
DDVINDQRNVIYKLRNNLLQEDTNMIEIIIPMIDHAVEAISKQYLVEGMLPEEWDFASLT
HHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
ASLNEILSVENMPSLSANNVHSPEDLQSVLKETLSLYKERVNELDSHTDLQQSLRYVALH
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
FLDQNWVNHLDAMTHLKEGIGLRQYQQEDPTRLYQKEALDIFLYTYGNFEKEMCRYVARH
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHH
LGVPENVQ
CCCCCCCC
>Mature Secondary Structure
MLNSVKKLLGDSQKRKLKKYEQLVQEINNLEEKLSDLSDEELRHKTITFKNMLRDGKTVD
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
DIKVEAFAVVREAAKRVLGLRHYDVQLIGGLVLLEGNIAEMPTGEGKTLVSSLPTYVRAL
HHHHHHHHHHHHHHHHHHCCCCCCHHEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
EGKGVHVITVNDYLAKRDKELIGQVHEFLGLKVGLNIPQIDPAEKKLAYEADITYGIGTE
CCCCEEEEEECHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHEEEECCCEECCCCH
FGFDYLRDNMAASKDEQVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKKSSSSDLHYLCAK
HHHHHHHHHHCCCCCHHHCCCEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
VIKSFQDTLHYTYDAETKSASFTEDGITKIEDLFDIDNLYDLEHQTLYHYMIQALRAHVA
HHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHEE
FQCDVDYIVHDEKILLVDIFTGRVMDGRSLSDGLHQALEAKEGLEITEENQTQASITIQN
EEECCCEEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHEEEHHH
FFRMYPALSGMTGTAKTEEKEFNRVYNMEVMPIPTNRPIIREDKKDVVYVTADAKYKAVR
HHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEECCCHHHHHH
EDVLKHNKQGRPILIGTMSILQSETVARYLDEANITYQLLNAKSAEQEADLIATAGQKGQ
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCE
ITIATNMAGRGTDILLGEGVHELGGLHVIGTERHESRRVDNQLKGRAGRQGDPGSSQFFL
EEEEECCCCCCCEEEECCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
SLEDEMLKRFAQEEVEKLMKSLKTDETGLILTSKVHDFVNRTQLICEGSHFSMREYNLKL
ECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHEEECCCCCCHHHCCCCH
DDVINDQRNVIYKLRNNLLQEDTNMIEIIIPMIDHAVEAISKQYLVEGMLPEEWDFASLT
HHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
ASLNEILSVENMPSLSANNVHSPEDLQSVLKETLSLYKERVNELDSHTDLQQSLRYVALH
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
FLDQNWVNHLDAMTHLKEGIGLRQYQQEDPTRLYQKEALDIFLYTYGNFEKEMCRYVARH
HHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHH
LGVPENVQ
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA