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The map label for this gene is alkA

Identifier: 222094621

GI number: 222094621

Start: 942038

End: 942655

Strand: Reverse

Name: alkA

Synonym: BCQ_0959

Alternate gene names: NA

Gene position: 942655-942038 (Counterclockwise)

Preceding gene: 222094623

Following gene: 222094617

Centisome position: 18.08

GC content: 41.42

Gene sequence:

>618_bases
ATGCAAGCACCACCTTCCTTTTATGAAGGCGATACGTTAGAAGTCGCAAAAAAATTACTCGGACAGAAACTTGTTCATAT
TGTAGATGGAATAAAGCGAAGTGGAATCATTGTTGAAGTAGAAGCATACAAAGGTCCGGGTGATAAGGCCGCACATAGTT
ACGGCGGCAGACGGACGGATCGTACGGAAGTCATGTTTGGTGCGCCAGGACATGCTTACGTATATTTAATTTACGGTATG
TACCATTGTTTTAACGTCATTACAGCACCAGTAGGCACCCCGCAAGGTGTTCTCATTCGAGCCCTTGAGCCGGTAGATGG
AATAGAAGAAATAAAACTAGCGCGCTATAACAAAACTGACATTACAAAGGCGCAGTATAAAAATTTAACGAACGGACCTG
GAAAATTATGTCGTGCCCTTGGAATCACTTTAGAAGAACGAGGCGTATCATTACAAAGTGACACATTGCATATTGAACTC
GTCCCAGAAGAAGAACACATATCATCACAATATAAAATAACAGCAGGACCTCGTATTAATATCGACTATGCAGAAGAAGC
TGTACATTATCCGTGGCGTTTTTATTATGAGGGGCATCCGTTTGTTTCAAAGAAATAA

Upstream 100 bases:

>100_bases
CATAATTTATGAAATAAATGTAGCAAATAGAACGAGTTAGAATTACTACTGAAAATTTGGTTTACTATATACATATACAC
TTAGTAAAGGAGATAGTACA

Downstream 100 bases:

>100_bases
AGTGAAACTTTAATCAGTGGGGAGTGCCTTCATCCCCCACTGATTATTAGTTGAACCAATCGGACTTTTATGGGCAGTTG
ATCCCCCGCCTAACTTCTTT

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPGDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGM
YHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIEL
VPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK

Sequences:

>Translated_205_residues
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPGDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGM
YHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIEL
VPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK
>Mature_205_residues
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPGDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGM
YHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIEL
VPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=203, Percent_Identity=39.4088669950739, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI62632765, Length=203, Percent_Identity=39.4088669950739, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI62632771, Length=203, Percent_Identity=39.4088669950739, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.21

Molecular weight: Translated: 22909; Mature: 22909

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPGDKAAHSYGGRRTD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCEEEEEEECCCCCCHHHHHCCCCCCC
RTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTD
CCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCC
ITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVPEEEHISSQYKITAGPRIN
CCHHHHCCCCCCHHHHHHHHCCEEHHCCCEEECCEEEEEEECCHHHCCCEEEEECCCEEE
IDYAEEAVHYPWRFYYEGHPFVSKK
EEHHHHHHCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPGDKAAHSYGGRRTD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCEEEEEEECCCCCCHHHHHCCCCCCC
RTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTD
CCEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCC
ITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVPEEEHISSQYKITAGPRIN
CCHHHHCCCCCCHHHHHHHHCCEEHHCCCEEECCEEEEEEECCHHHCCCEEEEECCCEEE
IDYAEEAVHYPWRFYYEGHPFVSKK
EEHHHHHHCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA