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The map label for this gene is resE [H]

Identifier: 222094336

GI number: 222094336

Start: 641429

End: 642892

Strand: Reverse

Name: resE [H]

Synonym: BCQ_0650

Alternate gene names: 222094336

Gene position: 642892-641429 (Counterclockwise)

Preceding gene: 222094337

Following gene: 222094335

Centisome position: 12.33

GC content: 33.27

Gene sequence:

>1464_bases
ATGAGTAAACTTTCACTTAAAATTGGGACATACTTTTTAATATTAGCTTTATGTATTGAAACAATTGCTTTTGTATCTTT
TTACAAAAGCATTTCAACAATGCGGATTGAGGAAGAAACACTTGCTCTTTTAGAAAAAGGTAATCGCTATAGTAACAAAA
TTACACAACGCGCAAAGTGGAGTGCATTTGCTAAAGAAAAGAAACACGGCGAACGCGCTGAATACAATAAAAATCCTAAG
CGTCCTATATACCCAGAGTTCGATATCGCTGATGAGGCTGAACACTTAGTTGAATCAGAATCAATCGCTAACTCTGATAT
AGCTATCATTATAACGGACAATAATGGAAAAATCATTTCCACTTCAGAACCTGTAACAAAGGCGATGCAAAAACAACTTA
CTTGTAAAACACAACATATTCCAGAAAACGGACTGGTTGTCGAAAAGAACTGGAAAAAATCAAAATTCATCACAACGGTA
AGCCCACTTAATACAGCAGAGTTTCAAGGAAAGTTATATATGTTATTAAAAACATCTTTTTTAGAAAATATGTTACTTAA
ACTCATGAACCAATTTCTTATCATTAGTGTTTTGACAGTTATTTTAACAACTATTTCTGTCTTTGTTTTTTCTCGTGTTA
TTACAGAACCGCTTATAAAAATGAAGAGGGCAACAGAAAAAATGTCAAAATTAAATAAACCAATTCAATTAGGTATTAAA
CGGAATGATGAACTTGGAAGCTTAGCAAAAACGATTGAAGATTTGTCCAGTGAGCTAACTTATATGAAAAAAGAACGCAA
TGAATTTCTTGCTAGTGTCGCCCATGAACTATTAACTCCATTGACCTATATGAAAGGTTATGCGAAAGTAGCAAAGCGAG
ACTCTTTAACGAAAGAAGAGCGTGAAGAATACTTGCAAATCATTGAGGATGAAACAGATAGTGTAACCGATCTCGTTCAA
GATTTATTTATGCTTGTACAATTAGAACAACACCAGTTTGTTATAAAAAAACAAAAAGTGCTTCTTAGGCCTTTTTTAGA
GCGAATGGTTGAAAAAACAAAAACAACATTAACGAATAAGCAAATGCAACTTCATGTATACTGTAAAGAGGATTTAGAAG
TATATATAGATGAAAGACGCATGGAACAAGTGATGTTAAATTTATTGCATAACGCTTATCAGCATTCACCAGAAAATACT
TCTATAACAATACGTGTACTAACGGAAACAGATTATTTTACAATAAGTGTACAAGACGAAGGCGAAGGTATTCCTGTGGA
AGATATCCCGCATATTTTCGATCGTTTTTATCGTGTTGATAAATCCAGAACGAGAGCTACTGGAGGAAAAGGTATCGGGC
TAGCTGTTGCAAAAGAAATTGTAGAATTGCATAATGGTTCCATTCTAGTAACAAGCCAATTAGAAGTAGGAACAAACTTT
ATAATTGAGCTACCTTTTGAATAA

Upstream 100 bases:

>100_bases
TCTATAAAGTCGGATATAAATGGAAAAGTGAATAATTACTTAGGTCAGTGAGCAATAGTATATCACTGACCCTTTATATG
AAATAAGGTATGGTGAGAAA

Downstream 100 bases:

>100_bases
GATGCGTGTGAAAACACCAGTAGTAGTAAACACTACTGGTGTTATTTTGTTCATAAAATCAGCTCATATAAGCTAAGCTT
TTGAAATTATTCTTATTTCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSKLSLKIGTYFLILALCIETIAFVSFYKSISTMRIEEETLALLEKGNRYSNKITQRAKWSAFAKEKKHGERAEYNKNPK
RPIYPEFDIADEAEHLVESESIANSDIAIIITDNNGKIISTSEPVTKAMQKQLTCKTQHIPENGLVVEKNWKKSKFITTV
SPLNTAEFQGKLYMLLKTSFLENMLLKLMNQFLIISVLTVILTTISVFVFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
RNDELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQ
DLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNKQMQLHVYCKEDLEVYIDERRMEQVMLNLLHNAYQHSPENT
SITIRVLTETDYFTISVQDEGEGIPVEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLEVGTNF
IIELPFE

Sequences:

>Translated_487_residues
MSKLSLKIGTYFLILALCIETIAFVSFYKSISTMRIEEETLALLEKGNRYSNKITQRAKWSAFAKEKKHGERAEYNKNPK
RPIYPEFDIADEAEHLVESESIANSDIAIIITDNNGKIISTSEPVTKAMQKQLTCKTQHIPENGLVVEKNWKKSKFITTV
SPLNTAEFQGKLYMLLKTSFLENMLLKLMNQFLIISVLTVILTTISVFVFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
RNDELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQ
DLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNKQMQLHVYCKEDLEVYIDERRMEQVMLNLLHNAYQHSPENT
SITIRVLTETDYFTISVQDEGEGIPVEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLEVGTNF
IIELPFE
>Mature_486_residues
SKLSLKIGTYFLILALCIETIAFVSFYKSISTMRIEEETLALLEKGNRYSNKITQRAKWSAFAKEKKHGERAEYNKNPKR
PIYPEFDIADEAEHLVESESIANSDIAIIITDNNGKIISTSEPVTKAMQKQLTCKTQHIPENGLVVEKNWKKSKFITTVS
PLNTAEFQGKLYMLLKTSFLENMLLKLMNQFLIISVLTVILTTISVFVFSRVITEPLIKMKRATEKMSKLNKPIQLGIKR
NDELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQD
LFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNKQMQLHVYCKEDLEVYIDERRMEQVMLNLLHNAYQHSPENTS
ITIRVLTETDYFTISVQDEGEGIPVEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLEVGTNFI
IELPFE

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=34.4978165938865, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=28.9855072463768, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786783, Length=415, Percent_Identity=25.3012048192771, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=24.896265560166, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789149, Length=222, Percent_Identity=29.7297297297297, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=301, Percent_Identity=24.5847176079734, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790861, Length=284, Percent_Identity=28.5211267605634, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=29.5964125560538, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=26.0683760683761, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787894, Length=336, Percent_Identity=23.5119047619048, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=28, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=29.646017699115, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082128, Length=297, Percent_Identity=25.5892255892256, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788279, Length=293, Percent_Identity=22.5255972696246, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=24.1228070175439, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790551, Length=303, Percent_Identity=26.7326732673267, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=231, Percent_Identity=29.004329004329, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787374, Length=316, Percent_Identity=22.1518987341772, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55996; Mature: 55865

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSLKIGTYFLILALCIETIAFVSFYKSISTMRIEEETLALLEKGNRYSNKITQRAKW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCHHHHHHHHHHHH
SAFAKEKKHGERAEYNKNPKRPIYPEFDIADEAEHLVESESIANSDIAIIITDNNGKIIS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
TSEPVTKAMQKQLTCKTQHIPENGLVVEKNWKKSKFITTVSPLNTAEFQGKLYMLLKTSF
CCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCCHHHCCHHHHHHHHHH
LENMLLKLMNQFLIISVLTVILTTISVFVFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
RNDELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
REEYLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QMQLHVYCKEDLEVYIDERRMEQVMLNLLHNAYQHSPENTSITIRVLTETDYFTISVQDE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECC
GEGIPVEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLEVGTNF
CCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEHCCCCCE
IIELPFE
EEECCCC
>Mature Secondary Structure 
SKLSLKIGTYFLILALCIETIAFVSFYKSISTMRIEEETLALLEKGNRYSNKITQRAKW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCHHHHHHHHHHHH
SAFAKEKKHGERAEYNKNPKRPIYPEFDIADEAEHLVESESIANSDIAIIITDNNGKIIS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
TSEPVTKAMQKQLTCKTQHIPENGLVVEKNWKKSKFITTVSPLNTAEFQGKLYMLLKTSF
CCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCCHHHCCHHHHHHHHHH
LENMLLKLMNQFLIISVLTVILTTISVFVFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
RNDELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
REEYLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QMQLHVYCKEDLEVYIDERRMEQVMLNLLHNAYQHSPENTSITIRVLTETDYFTISVQDE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECC
GEGIPVEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLEVGTNF
CCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEHCCCCCE
IIELPFE
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]