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The map label for this gene is perR [H]

Identifier: 222094272

GI number: 222094272

Start: 563218

End: 563613

Strand: Direct

Name: perR [H]

Synonym: BCQ_0565

Alternate gene names: 222094272

Gene position: 563218-563613 (Clockwise)

Preceding gene: 222094271

Following gene: 222094274

Centisome position: 10.8

GC content: 36.36

Gene sequence:

>396_bases
ATGCTGAAAAATACGGGTGTACGCATTACTCCACAGCGTCATGCTATTTTAGAGTACCTTGTGGAATCAATGACGCACCC
AACAGCGGATGATATTTATAAAGCATTAGAAGGTAAGTTTCCAAATATGAGTGTTGCAACTGTCTATAATAACTTACGTG
TATTTAAAGAGGTTGGGCTTGTAAAGGAATTAACTTATGGAGACGCTTCAAGTAGATTTGATTATGTTACAAGTCAACAT
TATCATGTGATTTGTGAAAAATGTGGTAAAATTGTTGATTTTCCTTATGGAGGTTTGGAACAACTTGAAGAGGAAGCTGC
AAAAACAACAGGCTTCGTTATTAATAGTCATCGCTTAGAAATTTATGGCGTTTGTCCAGAGTGTCATAAGGCGTAA

Upstream 100 bases:

>100_bases
AGAAAAGGAGTACACTCTTTATAAGAATTATAAAATAATAATCCGTATAGAATCGGGGTGCATGACGGTGGTCAAAGAAG
AATTAAAAGAAGCGCTAGAA

Downstream 100 bases:

>100_bases
TATATAATAAAGAAAGAGGCTGACGGCTTTACGTCAACCTCTTTCTTTATTATATATGGGAATTACGTTAGGTTCAGAAG
GAGTTAAAATGTTCAGTGGA

Product: ferric uptake regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDASSRFDYVTSQH
YHVICEKCGKIVDFPYGGLEQLEEEAAKTTGFVINSHRLEIYGVCPECHKA

Sequences:

>Translated_131_residues
MLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDASSRFDYVTSQH
YHVICEKCGKIVDFPYGGLEQLEEEAAKTTGFVINSHRLEIYGVCPECHKA
>Mature_131_residues
MLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDASSRFDYVTSQH
YHVICEKCGKIVDFPYGGLEQLEEEAAKTTGFVINSHRLEIYGVCPECHKA

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=128, Percent_Identity=34.375, Blast_Score=77, Evalue=5e-16,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 14816; Mature: 14816

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGL
CCCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VKELTYGDASSRFDYVTSQHYHVICEKCGKIVDFPYGGLEQLEEEAAKTTGFVINSHRLE
HHHHCCCCCCCCCCHHCCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCEEEECCEEE
IYGVCPECHKA
EEEECCHHCCC
>Mature Secondary Structure
MLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGL
CCCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VKELTYGDASSRFDYVTSQHYHVICEKCGKIVDFPYGGLEQLEEEAAKTTGFVINSHRLE
HHHHCCCCCCCCCCHHCCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCEEEECCEEE
IYGVCPECHKA
EEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]