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The map label for this gene is pbpX [H]

Identifier: 222094237

GI number: 222094237

Start: 527914

End: 529155

Strand: Direct

Name: pbpX [H]

Synonym: BCQ_0530

Alternate gene names: 222094237

Gene position: 527914-529155 (Clockwise)

Preceding gene: 222094236

Following gene: 222094238

Centisome position: 10.12

GC content: 34.46

Gene sequence:

>1242_bases
ATGGATCACGAAAAAAATAATGCGAATGGGAAATCACGTCGGCCGATTGTATACATAAAAAGAACAATCATTCTCGTCTT
ACTATTTTCACTTGTATATTTCATGTATACAAAAATTGTTGCGCATAATAAGAAAGAAGAAACTTTAAAAGTAGCAGCAG
AAATGAAGAAACAAGAAGAGCTAAAAAAGAAAGAAGAAAAAAAGAAGCAAGAAGCAAAAAAACAAATAGAGCAGGAAGAA
CAAGTGAAGCAAGCACAAGCTGCAGAACAGCCTGCTGAGGGACCACCTCAAGAAATTAATGAAAACGCTCAATTAGATCA
ATATTTGCAAAAAACAGGATTTAGCGGGACAGCGGTTATTGTGAAGAACGGAAAGGTTCTTTTGAATAAAGGATACGGTA
TGGCGAATAAAGAGAAACAAGTACCGAATAATTCAGAGACAACTTTTTATATTGGTTCTATTTCAAAGGCTTTTGTAGCG
ACTGCTATTATGCAATTAAAAGATCAAAATAAGTTAAATGTAGAGGATACGATTGCGAAGTATATTCCAGATTTCCCTCA
AGGTAATGGCATTCAGTTAAAACATTTACTAACACATACATCAGGAATTCCAGAGTACGAGCAGGGAACAGAGGATATCT
CTCATGAAGAATTGATAAAACGAATAGGAAAGCAAAAGCGTATTGGAAGTCCAGGAGAGAAATGGAAGTATTCCGATTCT
AACTATTCGATACTTGCCTATATTGCTGAGAAGGTAAGCGGACAACCGTTAGAAGAGTATATTAAACAACATGTTTTTGC
TACTGCTGGTATGAAACATTCTGGTTTTGGTAGAGAGCTAGAACAAACGAGATTTCCATCGACAGGTTATAAAATAGTAA
ATAACAATATGACAACACCTAATATTCCAAGTATGTCACAACTTTATGGTTGTGGTGATATATATACAAGTGCCCATGAT
TTATATTTATTTAATGAAGCGCTCTTCTCTGGAAAGTTGATTTCAAAAGAAAGCTACGATCAAATGTTTACAGGTGGAAA
AAAAGATTACGGGTTTGGATGGTACGTAGACCCGGGAAGTTATTCGAATCACGGTGTAATGCCAGGCTGGAACTGTTTAA
ATGGATTTAGTAAAAATGGTAGTGTGTATGTTGTTTTATTATCTAACATTCAAAACAACATTAAATCTTTTGGTAAAGTG
AATAATGACATTTATACGATGTTACGAAATATTGAAGTGTAA

Upstream 100 bases:

>100_bases
ATAAAGTAGGGATGACATAGAATGGATTATCCATAATCTACTAAAATAAATCTTTAGTAGAGAGATTAAATTATTGGTGA
ATAAGGGGAAAAAAGTAATC

Downstream 100 bases:

>100_bases
GAGACTATCTTTTTAGGTAGTCTTTTTTTTATGTGATTAGAACATATTGTTTCGTTGAAAAATGTATGTCTTACCTATCA
CAAAAAGAGTCTGCTTTGTA

Product: beta-lactamase (penicillin-binding protein) (penicillinase)

Products: substituted beta-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MDHEKNNANGKSRRPIVYIKRTIILVLLFSLVYFMYTKIVAHNKKEETLKVAAEMKKQEELKKKEEKKKQEAKKQIEQEE
QVKQAQAAEQPAEGPPQEINENAQLDQYLQKTGFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIGSISKAFVA
TAIMQLKDQNKLNVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPGEKWKYSDS
NYSILAYIAEKVSGQPLEEYIKQHVFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTPNIPSMSQLYGCGDIYTSAHD
LYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQNNIKSFGKV
NNDIYTMLRNIEV

Sequences:

>Translated_413_residues
MDHEKNNANGKSRRPIVYIKRTIILVLLFSLVYFMYTKIVAHNKKEETLKVAAEMKKQEELKKKEEKKKQEAKKQIEQEE
QVKQAQAAEQPAEGPPQEINENAQLDQYLQKTGFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIGSISKAFVA
TAIMQLKDQNKLNVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPGEKWKYSDS
NYSILAYIAEKVSGQPLEEYIKQHVFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTPNIPSMSQLYGCGDIYTSAHD
LYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQNNIKSFGKV
NNDIYTMLRNIEV
>Mature_413_residues
MDHEKNNANGKSRRPIVYIKRTIILVLLFSLVYFMYTKIVAHNKKEETLKVAAEMKKQEELKKKEEKKKQEAKKQIEQEE
QVKQAQAAEQPAEGPPQEINENAQLDQYLQKTGFSGTAVIVKNGKVLLNKGYGMANKEKQVPNNSETTFYIGSISKAFVA
TAIMQLKDQNKLNVEDTIAKYIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPGEKWKYSDS
NYSILAYIAEKVSGQPLEEYIKQHVFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTPNIPSMSQLYGCGDIYTSAHD
LYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGSYSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQNNIKSFGKV
NNDIYTMLRNIEV

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=Localizes to the division septum during vegetative growth, and accumulates at the prespore during sporulation [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=336, Percent_Identity=25, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786574, Length=340, Percent_Identity=22.3529411764706, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790593, Length=184, Percent_Identity=26.6304347826087, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=352, Percent_Identity=22.4431818181818, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6

Molecular weight: Translated: 46680; Mature: 46680

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHEKNNANGKSRRPIVYIKRTIILVLLFSLVYFMYTKIVAHNKKEETLKVAAEMKKQEE
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LKKKEEKKKQEAKKQIEQEEQVKQAQAAEQPAEGPPQEINENAQLDQYLQKTGFSGTAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCCCEEEE
VKNGKVLLNKGYGMANKEKQVPNNSETTFYIGSISKAFVATAIMQLKDQNKLNVEDTIAK
EECCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHH
YIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPGEKWKYSDS
HCCCCCCCCCEEHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCC
NYSILAYIAEKVSGQPLEEYIKQHVFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTP
CCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCEEECCCCCCC
NIPSMSQLYGCGDIYTSAHDLYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGS
CCCCHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEECCCC
YSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQNNIKSFGKVNNDIYTMLRNIEV
CCCCCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDHEKNNANGKSRRPIVYIKRTIILVLLFSLVYFMYTKIVAHNKKEETLKVAAEMKKQEE
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LKKKEEKKKQEAKKQIEQEEQVKQAQAAEQPAEGPPQEINENAQLDQYLQKTGFSGTAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCCCEEEE
VKNGKVLLNKGYGMANKEKQVPNNSETTFYIGSISKAFVATAIMQLKDQNKLNVEDTIAK
EECCEEEEECCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHH
YIPDFPQGNGIQLKHLLTHTSGIPEYEQGTEDISHEELIKRIGKQKRIGSPGEKWKYSDS
HCCCCCCCCCEEHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCC
NYSILAYIAEKVSGQPLEEYIKQHVFATAGMKHSGFGRELEQTRFPSTGYKIVNNNMTTP
CCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCEEECCCCCCC
NIPSMSQLYGCGDIYTSAHDLYLFNEALFSGKLISKESYDQMFTGGKKDYGFGWYVDPGS
CCCCHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEECCCC
YSNHGVMPGWNCLNGFSKNGSVYVVLLSNIQNNIKSFGKVNNDIYTMLRNIEV
CCCCCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-lactam; H2O

Specific reaction: A beta-lactam + H2O = a substituted beta-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]