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The map label for this gene is benK [H]

Identifier: 222094142

GI number: 222094142

Start: 423730

End: 425031

Strand: Reverse

Name: benK [H]

Synonym: BCQ_0435

Alternate gene names: 222094142

Gene position: 425031-423730 (Counterclockwise)

Preceding gene: 222094143

Following gene: 222094139

Centisome position: 8.15

GC content: 37.4

Gene sequence:

>1302_bases
ATGCAACCTTCAGCTCCACCTCATCTAGAATCTACAAAAACTATCTTTTTAAACTCTATTACAAAACTTGTTGTTTTTAT
TTGTTGGCTAGCCATTCTAGCTGACGGCTATGATTTAGGTATTTACGGGGCCGTTCTGCCTAAGCTACTGGAAGACAACA
GCTGGGCACTATCACCAGCTCATGCTGGTACAATTGCAAGCTATGCTTTGTTTGGTATGTTTATTGGCGCTATTCTAGTT
GGAACTATTACAGATCTAATTGGACGAAAATGGACGCTTATATGCTGTTTAGCACTTTTTTCTATCACAATGGGCCTAGC
TGCACTTGCTCCTTCTCCTGAATTATTTGGACTATGGCGATTTATCGGAGGAATTGGACTAGGCGGTGTCATTCCAACAG
CTTCCGCACTTACTGTTGAATATTCACCCAAAAAGCGACAATCTTTTATTTATGCTCTTATGTTTACTGGCTATCCTTTA
GGTATCGTGTTAGGCGCTATTTTGTCCATGTTTATGTTAGAAGACTTCGGATGGAGAATTATGTTTGGCATCGGAATGAT
TCCACTACTCCTCATTCCTTTCATTATTCGTTATTTACCTGAATCCATTCAATTTTTGTTATCACGTAACCGCCAAGAAG
AAGTGGATAAAATTCTTAATCGTTTTCAAATTGAATTCCATGCAAAAGAGAAAACTCATCAACCCCCATCTAATATACGA
AAGAAAAATGGATTTCTTACTTTATTCTCAAAAGAATACATAAAAGCAACGCTGCTTTTTTGGATCACTTATATAATGGG
GATGTTTTTAATATACGGTTTAAATACTTGGTTACCTCAGATGATGCGACAGGCAGGATATCCTCTTGGATCTAGTTTAT
CATTTCTACTTATGCTAAATATTACCGCCGCTATCGGTGCATTATTTGCTGGAGCAATCGCAGATCGTATAGGAGCCAAA
ATTGTTATTAGCATTTCCTATCTTATGGCAGCTGTATGTATTGGACTATTAACAATTAAACCATCTGTTACAATCATTTA
TCTTTTAATTGGTCTTGCTGGAATTGGATCGGTCGGTATTACTCAAATATTAAATGCATATGTGACACAATACTTCCCAT
CCCATATCCGAGCTACTTCCTTAGGCTGGGGACTTGGACTTGGCCGAGTTGGCGCAATTACTGGTCCTATTCTTGTCGGT
ATTATTATGACAATGCAATATGACTTAGTATGGAATTTTTACTTATTCTCATTTGCAGGTCTTCTTGCAGCTATATCTGT
TTTCTTTATTCCTACAAAATAA

Upstream 100 bases:

>100_bases
TTACTATAAAACTTTTTCATATAAATTCCGACATAAGAAGGGAAATATTAACATCAAATGAAATAATATATTCATCTACA
AATCAAAAGGGGTGAACATT

Downstream 100 bases:

>100_bases
AAAGAGCACAAACTTACTTGTGCTCTTTTTCGTATACCGCAAACAACATATCTCGAAACAATGTATTTAAACTCTCAATA
TCGATCCCTGATCCCTTTTC

Product: sugar transporter; benzoate transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MQPSAPPHLESTKTIFLNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGAILV
GTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPL
GIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQPPSNIR
KKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRIGAK
IVISISYLMAAVCIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAITGPILVG
IIMTMQYDLVWNFYLFSFAGLLAAISVFFIPTK

Sequences:

>Translated_433_residues
MQPSAPPHLESTKTIFLNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGAILV
GTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPL
GIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQPPSNIR
KKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRIGAK
IVISISYLMAAVCIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAITGPILVG
IIMTMQYDLVWNFYLFSFAGLLAAISVFFIPTK
>Mature_433_residues
MQPSAPPHLESTKTIFLNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPAHAGTIASYALFGMFIGAILV
GTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWRFIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPL
GIVLGAILSMFMLEDFGWRIMFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQPPSNIR
KKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLNITAAIGALFAGAIADRIGAK
IVISISYLMAAVCIGLLTIKPSVTIIYLLIGLAGIGSVGITQILNAYVTQYFPSHIRATSLGWGLGLGRVGAITGPILVG
IIMTMQYDLVWNFYLFSFAGLLAAISVFFIPTK

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=427, Percent_Identity=26.9320843091335, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI166064021, Length=369, Percent_Identity=24.6612466124661, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI216548223, Length=309, Percent_Identity=23.6245954692557, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI7662270, Length=309, Percent_Identity=22.3300970873786, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081723, Length=418, Percent_Identity=29.1866028708134, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI87082404, Length=426, Percent_Identity=24.1784037558685, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082159, Length=385, Percent_Identity=27.7922077922078, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788074, Length=368, Percent_Identity=25.2717391304348, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786229, Length=372, Percent_Identity=26.6129032258064, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788068, Length=406, Percent_Identity=25.8620689655172, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87082231, Length=413, Percent_Identity=20.0968523002421, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789312, Length=349, Percent_Identity=26.647564469914, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789207, Length=328, Percent_Identity=23.1707317073171, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790550, Length=427, Percent_Identity=25.7611241217799, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788292, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790463, Length=254, Percent_Identity=25.9842519685039, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=438, Percent_Identity=23.2876712328767, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71989525, Length=365, Percent_Identity=25.2054794520548, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71989531, Length=365, Percent_Identity=25.2054794520548, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322632, Length=126, Percent_Identity=36.5079365079365, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922874, Length=433, Percent_Identity=23.3256351039261, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24640198, Length=474, Percent_Identity=22.3628691983122, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640196, Length=474, Percent_Identity=22.3628691983122, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640200, Length=474, Percent_Identity=22.3628691983122, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668456, Length=359, Percent_Identity=25.9052924791086, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI62484254, Length=380, Percent_Identity=25.5263157894737, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47516; Mature: 47516

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSAPPHLESTKTIFLNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEECCC
HAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPLGIVLGAILSMFMLEDFGWRI
HHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
MFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQPPSNIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCHHHH
KKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLN
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ITAAIGALFAGAIADRIGAKIVISISYLMAAVCIGLLTIKPSVTIIYLLIGLAGIGSVGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
TQILNAYVTQYFPSHIRATSLGWGLGLGRVGAITGPILVGIIMTMQYDLVWNFYLFSFAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAAISVFFIPTK
HHHHHHHHHCCCC
>Mature Secondary Structure
MQPSAPPHLESTKTIFLNSITKLVVFICWLAILADGYDLGIYGAVLPKLLEDNSWALSPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEECCC
HAGTIASYALFGMFIGAILVGTITDLIGRKWTLICCLALFSITMGLAALAPSPELFGLWR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FIGGIGLGGVIPTASALTVEYSPKKRQSFIYALMFTGYPLGIVLGAILSMFMLEDFGWRI
HHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
MFGIGMIPLLLIPFIIRYLPESIQFLLSRNRQEEVDKILNRFQIEFHAKEKTHQPPSNIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCHHHH
KKNGFLTLFSKEYIKATLLFWITYIMGMFLIYGLNTWLPQMMRQAGYPLGSSLSFLLMLN
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ITAAIGALFAGAIADRIGAKIVISISYLMAAVCIGLLTIKPSVTIIYLLIGLAGIGSVGI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHH
TQILNAYVTQYFPSHIRATSLGWGLGLGRVGAITGPILVGIIMTMQYDLVWNFYLFSFAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAAISVFFIPTK
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]