Click here to switch to the map view.

The map label for this gene is nhaC [H]

Identifier: 222094118

GI number: 222094118

Start: 398452

End: 399873

Strand: Reverse

Name: nhaC [H]

Synonym: BCQ_0411

Alternate gene names: 222094118

Gene position: 399873-398452 (Counterclockwise)

Preceding gene: 222094121

Following gene: 222094116

Centisome position: 7.67

GC content: 37.27

Gene sequence:

>1422_bases
ATGAAAAAAGAAATACCTTTTGGTGTAGCCATGATCCCTATTATCATTACAGTTGCAGTTATGATGGTTACAATTGTTGT
ATTAAAACAAAGCCCTCACGTCCCACTTATTATCGGTACAACCGTTGCTTCCATCGTCGCTTGGCGTTACGGTTACAAAT
GGAACGACATTGAAGAAGCAATGTATAAAGGAATTCGCCTCGCATTACCCGCTATCGTTATCATTATTCTAGTAGGTTTA
ACGATCGGTGCTTGGATTGGTGGTGGAATCGTCGCAACAATGATTTATTACGGTTTAAATCTATTAACACCATCACTATT
TTTAGTTTCAATTACAATTATTTGTTCTATTGTTGCATTAGCTATTGGTAGCTCTTGGTCTACAATGGGAACAATTGGTG
TTGCAGGAATGGGTATTGGCCTAAGTATGGGAATCCCAGCTCCAATGGTTGCCGGTGCTATCATTTCCGGTTCTTATTTC
GGCGATAAAATGTCACCGCTTTCAGACACAACAAACTTAGCCGCAGGATTAACAAATACAGATTTATTCACACATATTCG
TCATATGTTATTTACTACAATTCCAGGTTTAATTATTACTCTTATCGTTTACGCGTTCTTAGGAAGAAGCTTCGGTGCTA
ACAATATCGATGCAAAAAGCATCGAGCAAACATTACAAGTATTGCAACAAAACTTTGTTATCTCACCTTTCCTATTAATC
ATACCTGTAGTTGTTATGGTATTGGTCGCTAAAAAAGTTCCTGCTATACCAGCTATTCTCGTAGGTATTATTTTAGGATT
TTTATCACAAGTCTTTATTCAAGGTGGTTCTGTCTCATCAGCTGTCGCTGCACTCCAAAGTGGATTTGTCATAGACACTG
GCAACAAGCTAGTAGACGAGCTATTTAATCGTGGTGGTTTAAGCTCTATGATGAATACCGTCTCTATGACAATTGTCGCT
ATGACTTTCGGAGGAGTATTAGAACATACAGGTATTCTTCGCTCCATTGTAAATCAAATTTTAAAATTAGCGACATCAGC
AAAAGGACTTATCGCTTCAACTATCGCATCTTGCTTTGCAACAAATCTTACTTGCTCTGAACAATATATTTCGATTGTTG
TTCCTTCAAGAATGTACGCGAATGCATACACAGAAAAAGGACTACATTCTAAAAATTTATCCAGAGCATTAGAAGATGGA
GGAACATTAACTTCTGTTTTTGTACCTTGGAATACATGCGGTGTATTTATACTCGCAACACTCGGCGTAGGTGCTTTCGA
ATATGCTCCTTATGCTATATTGAATTTCATCGTACCTATTATCTCGATTATTTACGGTATAACTGGTCTCACAATTACGA
AACTATCTGACATTGAAAAAGCGGAACTACTAAAGAAACAAAAAGCTCAATTAGAAGCTTAA

Upstream 100 bases:

>100_bases
CGCTTACATATATTTTTAGTTATCATAACCTAATAAACGTCTATTTTACGACAATTCTAAAAATACAAACAAACATACAT
ACATAACAAGGAGGACATTT

Downstream 100 bases:

>100_bases
AGATAACGGTAAATTCAGTTCATATATTGCGCGAGGACGCCCTTGTTGATAAGGCATTTCCTCGCCGCAAATATGAACAT
ATCCATAATCAACTAGTTTC

Product: Na+/H+ antiporter nhac

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MKKEIPFGVAMIPIIITVAVMMVTIVVLKQSPHVPLIIGTTVASIVAWRYGYKWNDIEEAMYKGIRLALPAIVIIILVGL
TIGAWIGGGIVATMIYYGLNLLTPSLFLVSITIICSIVALAIGSSWSTMGTIGVAGMGIGLSMGIPAPMVAGAIISGSYF
GDKMSPLSDTTNLAAGLTNTDLFTHIRHMLFTTIPGLIITLIVYAFLGRSFGANNIDAKSIEQTLQVLQQNFVISPFLLI
IPVVVMVLVAKKVPAIPAILVGIILGFLSQVFIQGGSVSSAVAALQSGFVIDTGNKLVDELFNRGGLSSMMNTVSMTIVA
MTFGGVLEHTGILRSIVNQILKLATSAKGLIASTIASCFATNLTCSEQYISIVVPSRMYANAYTEKGLHSKNLSRALEDG
GTLTSVFVPWNTCGVFILATLGVGAFEYAPYAILNFIVPIISIIYGITGLTITKLSDIEKAELLKKQKAQLEA

Sequences:

>Translated_473_residues
MKKEIPFGVAMIPIIITVAVMMVTIVVLKQSPHVPLIIGTTVASIVAWRYGYKWNDIEEAMYKGIRLALPAIVIIILVGL
TIGAWIGGGIVATMIYYGLNLLTPSLFLVSITIICSIVALAIGSSWSTMGTIGVAGMGIGLSMGIPAPMVAGAIISGSYF
GDKMSPLSDTTNLAAGLTNTDLFTHIRHMLFTTIPGLIITLIVYAFLGRSFGANNIDAKSIEQTLQVLQQNFVISPFLLI
IPVVVMVLVAKKVPAIPAILVGIILGFLSQVFIQGGSVSSAVAALQSGFVIDTGNKLVDELFNRGGLSSMMNTVSMTIVA
MTFGGVLEHTGILRSIVNQILKLATSAKGLIASTIASCFATNLTCSEQYISIVVPSRMYANAYTEKGLHSKNLSRALEDG
GTLTSVFVPWNTCGVFILATLGVGAFEYAPYAILNFIVPIISIIYGITGLTITKLSDIEKAELLKKQKAQLEA
>Mature_473_residues
MKKEIPFGVAMIPIIITVAVMMVTIVVLKQSPHVPLIIGTTVASIVAWRYGYKWNDIEEAMYKGIRLALPAIVIIILVGL
TIGAWIGGGIVATMIYYGLNLLTPSLFLVSITIICSIVALAIGSSWSTMGTIGVAGMGIGLSMGIPAPMVAGAIISGSYF
GDKMSPLSDTTNLAAGLTNTDLFTHIRHMLFTTIPGLIITLIVYAFLGRSFGANNIDAKSIEQTLQVLQQNFVISPFLLI
IPVVVMVLVAKKVPAIPAILVGIILGFLSQVFIQGGSVSSAVAALQSGFVIDTGNKLVDELFNRGGLSSMMNTVSMTIVA
MTFGGVLEHTGILRSIVNQILKLATSAKGLIASTIASCFATNLTCSEQYISIVVPSRMYANAYTEKGLHSKNLSRALEDG
GTLTSVFVPWNTCGVFILATLGVGAFEYAPYAILNFIVPIISIIYGITGLTITKLSDIEKAELLKKQKAQLEA

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 50172; Mature: 50172

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]