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The map label for this gene is arsA

Identifier: 222094074

GI number: 222094074

Start: 344596

End: 345774

Strand: Reverse

Name: arsA

Synonym: BCQ_0367

Alternate gene names: NA

Gene position: 345774-344596 (Counterclockwise)

Preceding gene: 222094075

Following gene: 222094073

Centisome position: 6.63

GC content: 36.3

Gene sequence:

>1179_bases
ATGAGAATTATCTTGTATACAGGTAAAGGCGGCGTAGGAAAAACTAGCATTTCAGCAGCAACAGCAATTCAAAGTGCGAA
ACAAGGATTAAAAACTTTAGTAATGAGCACAGATCCTGCTCATAGTTTAGGAGATTCATTTGGTATAAAGCTATCTTCTG
AGCCATTAGAAGTTCGTAAAAATTTGTGGGCACAAGAAATTAATACGATTTATGAGATGGAAAAAGGCTGGGGAAAATTA
CAGAAATATATTACACTACTCTTCACTTCCAAAGCAGCCGATGATATTACAACAGAAGAATTAACGATGTTTCCTGGTAT
GGAAGATTTAATTAGCTTACTTCGCGTGCTCGATTATTATAAACAAAACACATATGACGTTATTATCATTGATTGTGCTC
CAACAGGAGAAACATTAGCAATGCTCAGCTTTCCAGACATGCTCGGCTGGTGGATGGAAAAACTCTTTCCTATTAAAAGA
AAAGTTTTAAAAGTTGTTCGCCCTGTAGCTCAACCACTTCTTGGTGTCCCCCTTCCAACCGATGATATTATGGACGAATT
AACAAATACACTTGAACAACTCGGAGAAATGAGGGATATTTTATCAAACCGAGACGTAACGAGTATCCGCATCGTTGTAA
ATCCCGAAAAAATGGTCATTAAAGAAGCACAGCGCAGCTTTACGTATTTAAATCTATACGATTATAACGTAGATGCCATT
ATGATCAATCGTGTCATTCCTAACACTGTCACCGATCCTTATTTTCAAGCATGGAAAGATACCCAAAAGAAATATAAAAC
ATTAATTCAAGATAGTTTTGATCCACTTCCTATTTACGAAGCTCCAATGTTTGAACAAGAAGTTGTTGGTTTACCTATGT
TAGAACGTGTAGGAGATACTTTATTTAAAACGGATCATTGTCCTACTGAAGTAAAATTTAACGGTCGCACTCAATATGTA
AAAAAAGATGGCGATGAATATATTTTCGTTTTGTCCATTCCCTTCTCTAACAAAAGTGAACTTGCATTAAATCAAAAAGG
CGATGAGCTTATCATTCGTGCTGGTTCTGTTAAGCGGAACATCACATTACCCAAAACGTTAACACATCTTTCTATTCAAG
GAGCAAAATTCGAAGATGATGTACTAAACATTCGATTTGGAGGTGTCGTACATGCATGA

Upstream 100 bases:

>100_bases
AAAACATTCCGATTGAATAAAAACCCTAATAGGGTTTTTATTCAAAAAAATACTTCGACACTCGTAATATTCGATATTCG
AAACAAAGGGGATATGAATG

Downstream 100 bases:

>100_bases
AGAACTACTAAGGAAAGTCATCCGTACAAAAATAAAAGTAGGTATGCATATATTAGAAGAGTTACCTACCCCAATCCAGC
AATCAGCTAAGCAAATGCTA

Product: arsenite-transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRIILYTGKGGVGKTSISAATAIQSAKQGLKTLVMSTDPAHSLGDSFGIKLSSEPLEVRKNLWAQEINTIYEMEKGWGKL
QKYITLLFTSKAADDITTEELTMFPGMEDLISLLRVLDYYKQNTYDVIIIDCAPTGETLAMLSFPDMLGWWMEKLFPIKR
KVLKVVRPVAQPLLGVPLPTDDIMDELTNTLEQLGEMRDILSNRDVTSIRIVVNPEKMVIKEAQRSFTYLNLYDYNVDAI
MINRVIPNTVTDPYFQAWKDTQKKYKTLIQDSFDPLPIYEAPMFEQEVVGLPMLERVGDTLFKTDHCPTEVKFNGRTQYV
KKDGDEYIFVLSIPFSNKSELALNQKGDELIIRAGSVKRNITLPKTLTHLSIQGAKFEDDVLNIRFGGVVHA

Sequences:

>Translated_392_residues
MRIILYTGKGGVGKTSISAATAIQSAKQGLKTLVMSTDPAHSLGDSFGIKLSSEPLEVRKNLWAQEINTIYEMEKGWGKL
QKYITLLFTSKAADDITTEELTMFPGMEDLISLLRVLDYYKQNTYDVIIIDCAPTGETLAMLSFPDMLGWWMEKLFPIKR
KVLKVVRPVAQPLLGVPLPTDDIMDELTNTLEQLGEMRDILSNRDVTSIRIVVNPEKMVIKEAQRSFTYLNLYDYNVDAI
MINRVIPNTVTDPYFQAWKDTQKKYKTLIQDSFDPLPIYEAPMFEQEVVGLPMLERVGDTLFKTDHCPTEVKFNGRTQYV
KKDGDEYIFVLSIPFSNKSELALNQKGDELIIRAGSVKRNITLPKTLTHLSIQGAKFEDDVLNIRFGGVVHA
>Mature_392_residues
MRIILYTGKGGVGKTSISAATAIQSAKQGLKTLVMSTDPAHSLGDSFGIKLSSEPLEVRKNLWAQEINTIYEMEKGWGKL
QKYITLLFTSKAADDITTEELTMFPGMEDLISLLRVLDYYKQNTYDVIIIDCAPTGETLAMLSFPDMLGWWMEKLFPIKR
KVLKVVRPVAQPLLGVPLPTDDIMDELTNTLEQLGEMRDILSNRDVTSIRIVVNPEKMVIKEAQRSFTYLNLYDYNVDAI
MINRVIPNTVTDPYFQAWKDTQKKYKTLIQDSFDPLPIYEAPMFEQEVVGLPMLERVGDTLFKTDHCPTEVKFNGRTQYV
KKDGDEYIFVLSIPFSNKSELALNQKGDELIIRAGSVKRNITLPKTLTHLSIQGAKFEDDVLNIRFGGVVHA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=278, Percent_Identity=24.8201438848921, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17557003, Length=297, Percent_Identity=23.5690235690236, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320103, Length=313, Percent_Identity=25.2396166134185, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586297, Length=304, Percent_Identity=25.3289473684211, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 44378; Mature: 44378

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILYTGKGGVGKTSISAATAIQSAKQGLKTLVMSTDPAHSLGDSFGIKLSSEPLEVRK
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEHCCCCCCHHCCCCCCCEECCCHHHHHH
NLWAQEINTIYEMEKGWGKLQKYITLLFTSKAADDITTEELTMFPGMEDLISLLRVLDYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCCHHHHHHHHHHHHHH
KQNTYDVIIIDCAPTGETLAMLSFPDMLGWWMEKLFPIKRKVLKVVRPVAQPLLGVPLPT
HCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DDIMDELTNTLEQLGEMRDILSNRDVTSIRIVVNPEKMVIKEAQRSFTYLNLYDYNVDAI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCEEEEEEEECCCCEE
MINRVIPNTVTDPYFQAWKDTQKKYKTLIQDSFDPLPIYEAPMFEQEVVGLPMLERVGDT
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHCHH
LFKTDHCPTEVKFNGRTQYVKKDGDEYIFVLSIPFSNKSELALNQKGDELIIRAGSVKRN
HHCCCCCCCEEEECCCEEEEECCCCCEEEEEEECCCCCCCEEECCCCCEEEEEECCCCCC
ITLPKTLTHLSIQGAKFEDDVLNIRFGGVVHA
CCCCHHHHEEEECCCCCCCCEEEEEECCEECC
>Mature Secondary Structure
MRIILYTGKGGVGKTSISAATAIQSAKQGLKTLVMSTDPAHSLGDSFGIKLSSEPLEVRK
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEHCCCCCCHHCCCCCCCEECCCHHHHHH
NLWAQEINTIYEMEKGWGKLQKYITLLFTSKAADDITTEELTMFPGMEDLISLLRVLDYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCCHHHHHHHHHHHHHH
KQNTYDVIIIDCAPTGETLAMLSFPDMLGWWMEKLFPIKRKVLKVVRPVAQPLLGVPLPT
HCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DDIMDELTNTLEQLGEMRDILSNRDVTSIRIVVNPEKMVIKEAQRSFTYLNLYDYNVDAI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHCEEEEEEEECCCCEE
MINRVIPNTVTDPYFQAWKDTQKKYKTLIQDSFDPLPIYEAPMFEQEVVGLPMLERVGDT
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHCHH
LFKTDHCPTEVKFNGRTQYVKKDGDEYIFVLSIPFSNKSELALNQKGDELIIRAGSVKRN
HHCCCCCCCEEEECCCEEEEECCCCCEEEEEEECCCCCCCEEECCCCCEEEEEECCCCCC
ITLPKTLTHLSIQGAKFEDDVLNIRFGGVVHA
CCCCHHHHEEEECCCCCCCCEEEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]