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The map label for this gene is purQ [H]

Identifier: 222094052

GI number: 222094052

Start: 319855

End: 320538

Strand: Direct

Name: purQ [H]

Synonym: BCQ_0345

Alternate gene names: 222094052

Gene position: 319855-320538 (Clockwise)

Preceding gene: 222094051

Following gene: 222094053

Centisome position: 6.13

GC content: 37.72

Gene sequence:

>684_bases
GTGAAATTTGCCGTAATAGTATTTCCAGGTTCGAACTGTGATGTTGATATGTTCCATGCAATTAAAGATGAGCTTGGCGA
AGAAGTAGATTACGTTTGGCACGACACAGAGAATTTAGATGAATATGATGCAATTCTACTACCAGGTGGATTCTCTTACG
GTGACTACTTACGCTGCGGTGCTATTTCTCGCTTTGCGAATGCAATGAAAGCAGTACAAAAAGCTGCTGAGCAAGGAAAG
CCAATTTTAGGTGTATGTAATGGATTCCAGATTCTTGTTGAATCAGGATTACTACCAGGAGCATTAATGAGAAACGAAAA
CTTAAAATTTATGTGTCGAACAGTTCAGTTACGTGTTGAAAATAATGAAACGATGTTTACATCACAATATGAAAAAGATG
AAGTAATCAATATTCCAATTGCACATGGTGAGGGAAATTACTATTGTGATGAAGAGACTCTTAAAAAATTAGAAGAGAAT
AATCAGATCGCATTCCGTTACGTAGAAAACCCGAACGGAAGCGTTTCAGATATTGCTGGTATTGTAAACGAAAAAGGAAA
TGTACTTGGTATGATGCCACACCCAGAGCGTGCTGTAGATGAATTACTTGGCGGTGCTGAAGGGTTAAAAGTCTTTCAAT
CTATCTTAAAACAGTGGAGGGAAACATATGTCGTTAATGCTTGA

Upstream 100 bases:

>100_bases
TATCTGACCTTGACGCAAAGGTAAAGGAAATGTGTGAAAAACTATTAGCGAACGTTGTAATGGAAGACTTCCGTTATGAA
GTTGAGGAGGTTGTCGCACA

Downstream 100 bases:

>100_bases
ACCAAATCCAACACAAATTAAAGAAGAGCGCATATATGCGGAAATGGGGCTAACAGACGAAGAGTTTGCCATGGTTGAAA
AGATTTTAGGCCGTCTGCCA

Product: phosphoribosylformylglycinamidine synthase i

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKKLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA

Sequences:

>Translated_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKKLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
>Mature_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKKLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=246, Percent_Identity=29.6747967479675, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17553022, Length=235, Percent_Identity=26.8085106382979, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=243, Percent_Identity=30.0411522633745, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24582111, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582109, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17137292, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25411; Mature: 25411

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCHHCEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCHHHCCCCCEEEEEEEEEEEC
NNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKKLEENNQIAFRYVENPNGSVSDIAG
CCCEEEECCCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCHHCEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCHHHCCCCCEEEEEEEEEEEC
NNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKKLEENNQIAFRYVENPNGSVSDIAG
CCCEEEECCCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA