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The map label for this gene is yprA [H]

Identifier: 221636125

GI number: 221636125

Start: 709748

End: 712267

Strand: Reverse

Name: yprA [H]

Synonym: trd_A0719

Alternate gene names: 221636125

Gene position: 712267-709748 (Counterclockwise)

Preceding gene: 221636126

Following gene: 221636124

Centisome position: 77.61

GC content: 66.15

Gene sequence:

>2520_bases
ATGCTCTCAACGGATTTTGTCGAGCATTTACTCGCCGATGCGGGTCTCTGCGTGCGTGAGCGACAGACCATTCCTGGTCG
CGACGCAACTTTCGCCCCCGTCCCGGCCACGCTCCACCCGCGTGTCGCCGACCTCCTCCGCGGCCGCTTCCCGGCTGGCC
TGTGGAAGCACCAGGCGGTCGCGATCGACCGGGCTCTCGCGGGGGAGTCGGTCTGCATCACGACGCAGACGGCCTCGGGC
AAGAGCCTTATCTTCATGGCCGTCGCGGCGCACCGGCTGCTGACGGAACCCTCTGCGTGCGTCCTCACCTTCTACCCCGC
CCGAGCACTCATCCAGGATCAGCTCGCGAAGTGGCGTGATCTGCTCGATCCGCTCGGGCTCACCTTCGGGTATATCGATG
GTGGCGTGCAGGTGGAGCGACGCCCCGATATCCTGCGTCGTCATCGCCTCGTCCTGATGACGCCGGACGTGGCGCACGCG
TGGCTCCTGCCGAACGCCGGTGAGACCTGGGCGAGGTCGTTCCTGCAATGCCTCTCGCTCCTGATCCTGGACGAGGCCCA
CGTGTACGAGGGGGTGTTCGGCACCAACTTCGCCTACCTCATACGGCGCCTCCTAGCACTGTCGACGCTACGGCAGGTGC
TCGCGGTGAGTGCCACGCTCGACGATCCGGAAGCCTTTCTCCGCCAGTTGACCGGATTGTCCGTGGCTGTGCTCGGCGCG
TCGGACGACTGCGCACCGGTTTATGAGAAAACGGTGCTCTTGGCTGGGAGATCCCCGGGTGCAGGCCTGCGCGCAGGTCG
CCGGAGCGACGACTTCAAGACCGTCGTCGACGTCGTCCGGCGGCTTGCCGAAGCTCTGCCGACCCCCTTCCTCGCCTTCG
CCGACTCGCGCCGGATGGTCGAGCACGTGGTCGCCGCGCTCCACCGGCAACCGACGGAGAGCGCCCCCGACAGCGACGAC
GAGCACGATCAGGCCGCGCCGGTGAACTGGATGGTGCTCCCGTACCGGGCAGGCTATGAGGAAGAGGACAGGATCGAGAT
CCAGCGCTCGCTGGCTGCAGGCTCCCTCAGGGGAGTCGTCTCGACCAGCGCGCTCGAGCTCGGCATCGACATCGGCCATA
TCGACGTCGTCGCCATGTTGCAGCCGCCTCCGACGCGCAAAGCGTTCTGGCAGCGCCTCGGCCGCGCGGGTCGGAGCCGC
CCCGGCCTTTGTATCCTGCTCGATCTCGAGGATCGGTTCTCACTCGGTCACTTCCTCGAAAGCCGGAGCGAACCGAACTG
CCTGTACCTCGAAAACCGCTATCTCCAGTACGCCAACGTCCTCTGCGCGGTGGCCGAGCTCGCCAGCACCGGGAGCGGGA
GAGAGGCCCTCGCTCGGTACGTCGAGGTGCCGCCGGATTTCCTCCGGCTCCTCGAGAACGAGCTGGAGCCGACCGAACCT
GTCCCGCCCGAGCTTGCCGTCCTAAAGCAACGCGCCCAAGCCAGCCCGCACCTCGAGTTCCCGCTGCGCGACATGATCGA
CGAGGTGTTCGACGTGCAAGACCGTAGCGGCCGCCGTCTCGGACAGGTCACCTACACCCAGGCTCTCCGCGAAGCCTATC
CGGGCGCGGTCTACTATTACCTGGCGCAGCCGTACCGGGTCGTCCACTTCAACTTTCGCGCCAAGCGGATCGAGGTAAGG
CGCGAGAAGCGCTACACGACTCGGCCGGACCTCTTGCAGCGCGCCTTTCCCCGCTGGCCAGAGGGCTTACTGGCACTCTG
GAAGGGCGCTGACTGCGGGTTCGTCGCAGAGTCGGAGATGCAGGTCATGGAGAAGTTGCAAGGATTCACTGAACAGCGCG
GCAGCGCACGAGAGCAGCACCGCTACGAGCCTGGGTCGGTCTACTACCAGCGGCCGCTCCTCCGGTTCTTCGAGACGACC
GGCGTGGCCTGGTGGTTTCCGAGCGCGAAGCTCAACGAGGAACTCGCCCGGCTCGTCCTCCTCAGCTTCTGCGACCTCTG
CGGGGTACAGGAACACGACGTCGCCCTCGGCATGTTCCACGCCAAGCAGTCGCCTGTCCAGCCTGACGAAGTCTCCGGCT
GGTGCATCTACGACAGTACCTATGGGAGCCTGCGACTCACACAGCGGCTCGGTGAACGGTTCCGAGAGGTCGCCTGGGAG
GCACTGGAGCGGTGCCCGGACGACCAACCCTGTGAGGCTCTCCGGGCACTCGCCCAAGCTACCGAAGGAATCGCACGCGC
GCCGGTCGAGCGCCCGTCACCGGAGGTGTCAGTCAGCGACGAGTGGGTGGTCGTGATCGCGCGGGGCGAGCAGGCCATCT
ACTTCAAGGCCGAGGCGAGCGAGGAGGTGCTCATCAAAGACTTCCGCTATACGCCTCGCGGCATCGTGTACGATCTCGAG
CCGGGAGGCGGCTGGGACACGCGTCGCGTGCCAGCGGAGTTCGTCAAGCCGATACGCGGGGTCACTCGTCTGATCCTGTA
CAACCTGGAAACCGGGGAAGAGCGGCCGCACGAGGAGTAG

Upstream 100 bases:

>100_bases
CACCTCTCGACTGCGCGATACTCTCGGGCTCGAGCCAAGGGGCCGGTCTCGGATAGGCGTTTTCGTCGATCCGCTCGTTT
CAACCGGGAAGGAGGCCGCC

Downstream 100 bases:

>100_bases
CTTCGCCCCACAAGGCGTGGCGCCGCTCGGGTACAGCCAGCCCGGGTGGACGCTTCCTGCTCCCCATCGACGGCGGAGCG
ACGACTATGCACCCGCCGCT

Product: ATP-dependent helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 839; Mature: 839

Protein sequence:

>839_residues
MLSTDFVEHLLADAGLCVRERQTIPGRDATFAPVPATLHPRVADLLRGRFPAGLWKHQAVAIDRALAGESVCITTQTASG
KSLIFMAVAAHRLLTEPSACVLTFYPARALIQDQLAKWRDLLDPLGLTFGYIDGGVQVERRPDILRRHRLVLMTPDVAHA
WLLPNAGETWARSFLQCLSLLILDEAHVYEGVFGTNFAYLIRRLLALSTLRQVLAVSATLDDPEAFLRQLTGLSVAVLGA
SDDCAPVYEKTVLLAGRSPGAGLRAGRRSDDFKTVVDVVRRLAEALPTPFLAFADSRRMVEHVVAALHRQPTESAPDSDD
EHDQAAPVNWMVLPYRAGYEEEDRIEIQRSLAAGSLRGVVSTSALELGIDIGHIDVVAMLQPPPTRKAFWQRLGRAGRSR
PGLCILLDLEDRFSLGHFLESRSEPNCLYLENRYLQYANVLCAVAELASTGSGREALARYVEVPPDFLRLLENELEPTEP
VPPELAVLKQRAQASPHLEFPLRDMIDEVFDVQDRSGRRLGQVTYTQALREAYPGAVYYYLAQPYRVVHFNFRAKRIEVR
REKRYTTRPDLLQRAFPRWPEGLLALWKGADCGFVAESEMQVMEKLQGFTEQRGSAREQHRYEPGSVYYQRPLLRFFETT
GVAWWFPSAKLNEELARLVLLSFCDLCGVQEHDVALGMFHAKQSPVQPDEVSGWCIYDSTYGSLRLTQRLGERFREVAWE
ALERCPDDQPCEALRALAQATEGIARAPVERPSPEVSVSDEWVVVIARGEQAIYFKAEASEEVLIKDFRYTPRGIVYDLE
PGGGWDTRRVPAEFVKPIRGVTRLILYNLETGEERPHEE

Sequences:

>Translated_839_residues
MLSTDFVEHLLADAGLCVRERQTIPGRDATFAPVPATLHPRVADLLRGRFPAGLWKHQAVAIDRALAGESVCITTQTASG
KSLIFMAVAAHRLLTEPSACVLTFYPARALIQDQLAKWRDLLDPLGLTFGYIDGGVQVERRPDILRRHRLVLMTPDVAHA
WLLPNAGETWARSFLQCLSLLILDEAHVYEGVFGTNFAYLIRRLLALSTLRQVLAVSATLDDPEAFLRQLTGLSVAVLGA
SDDCAPVYEKTVLLAGRSPGAGLRAGRRSDDFKTVVDVVRRLAEALPTPFLAFADSRRMVEHVVAALHRQPTESAPDSDD
EHDQAAPVNWMVLPYRAGYEEEDRIEIQRSLAAGSLRGVVSTSALELGIDIGHIDVVAMLQPPPTRKAFWQRLGRAGRSR
PGLCILLDLEDRFSLGHFLESRSEPNCLYLENRYLQYANVLCAVAELASTGSGREALARYVEVPPDFLRLLENELEPTEP
VPPELAVLKQRAQASPHLEFPLRDMIDEVFDVQDRSGRRLGQVTYTQALREAYPGAVYYYLAQPYRVVHFNFRAKRIEVR
REKRYTTRPDLLQRAFPRWPEGLLALWKGADCGFVAESEMQVMEKLQGFTEQRGSAREQHRYEPGSVYYQRPLLRFFETT
GVAWWFPSAKLNEELARLVLLSFCDLCGVQEHDVALGMFHAKQSPVQPDEVSGWCIYDSTYGSLRLTQRLGERFREVAWE
ALERCPDDQPCEALRALAQATEGIARAPVERPSPEVSVSDEWVVVIARGEQAIYFKAEASEEVLIKDFRYTPRGIVYDLE
PGGGWDTRRVPAEFVKPIRGVTRLILYNLETGEERPHEE
>Mature_839_residues
MLSTDFVEHLLADAGLCVRERQTIPGRDATFAPVPATLHPRVADLLRGRFPAGLWKHQAVAIDRALAGESVCITTQTASG
KSLIFMAVAAHRLLTEPSACVLTFYPARALIQDQLAKWRDLLDPLGLTFGYIDGGVQVERRPDILRRHRLVLMTPDVAHA
WLLPNAGETWARSFLQCLSLLILDEAHVYEGVFGTNFAYLIRRLLALSTLRQVLAVSATLDDPEAFLRQLTGLSVAVLGA
SDDCAPVYEKTVLLAGRSPGAGLRAGRRSDDFKTVVDVVRRLAEALPTPFLAFADSRRMVEHVVAALHRQPTESAPDSDD
EHDQAAPVNWMVLPYRAGYEEEDRIEIQRSLAAGSLRGVVSTSALELGIDIGHIDVVAMLQPPPTRKAFWQRLGRAGRSR
PGLCILLDLEDRFSLGHFLESRSEPNCLYLENRYLQYANVLCAVAELASTGSGREALARYVEVPPDFLRLLENELEPTEP
VPPELAVLKQRAQASPHLEFPLRDMIDEVFDVQDRSGRRLGQVTYTQALREAYPGAVYYYLAQPYRVVHFNFRAKRIEVR
REKRYTTRPDLLQRAFPRWPEGLLALWKGADCGFVAESEMQVMEKLQGFTEQRGSAREQHRYEPGSVYYQRPLLRFFETT
GVAWWFPSAKLNEELARLVLLSFCDLCGVQEHDVALGMFHAKQSPVQPDEVSGWCIYDSTYGSLRLTQRLGERFREVAWE
ALERCPDDQPCEALRALAQATEGIARAPVERPSPEVSVSDEWVVVIARGEQAIYFKAEASEEVLIKDFRYTPRGIVYDLE
PGGGWDTRRVPAEFVKPIRGVTRLILYNLETGEERPHEE

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=396, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320497, Length=565, Percent_Identity=28.4955752212389, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 94351; Mature: 94351

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTDFVEHLLADAGLCVRERQTIPGRDATFAPVPATLHPRVADLLRGRFPAGLWKHQAV
CCCHHHHHHHHHHCCCEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHH
AIDRALAGESVCITTQTASGKSLIFMAVAAHRLLTEPSACVLTFYPARALIQDQLAKWRD
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
LLDPLGLTFGYIDGGVQVERRPDILRRHRLVLMTPDVAHAWLLPNAGETWARSFLQCLSL
HHHHHCCEEEEECCCEEECCCHHHHHCCEEEEECCCCHHEEECCCCCHHHHHHHHHHHHH
LILDEAHVYEGVFGTNFAYLIRRLLALSTLRQVLAVSATLDDPEAFLRQLTGLSVAVLGA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEC
SDDCAPVYEKTVLLAGRSPGAGLRAGRRSDDFKTVVDVVRRLAEALPTPFLAFADSRRMV
CCCCCHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EHVVAALHRQPTESAPDSDDEHDQAAPVNWMVLPYRAGYEEEDRIEIQRSLAAGSLRGVV
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
STSALELGIDIGHIDVVAMLQPPPTRKAFWQRLGRAGRSRPGLCILLDLEDRFSLGHFLE
HHHHHHCCCEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHH
SRSEPNCLYLENRYLQYANVLCAVAELASTGSGREALARYVEVPPDFLRLLENELEPTEP
CCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCC
VPPELAVLKQRAQASPHLEFPLRDMIDEVFDVQDRSGRRLGQVTYTQALREAYPGAVYYY
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
LAQPYRVVHFNFRAKRIEVRREKRYTTRPDLLQRAFPRWPEGLLALWKGADCGFVAESEM
ECCCEEEEEEECHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHH
QVMEKLQGFTEQRGSAREQHRYEPGSVYYQRPLLRFFETTGVAWWFPSAKLNEELARLVL
HHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHH
LSFCDLCGVQEHDVALGMFHAKQSPVQPDEVSGWCIYDSTYGSLRLTQRLGERFREVAWE
HHHHHHCCCCCCCHHEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ALERCPDDQPCEALRALAQATEGIARAPVERPSPEVSVSDEWVVVIARGEQAIYFKAEAS
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCEEEEEEECCC
EEVLIKDFRYTPRGIVYDLEPGGGWDTRRVPAEFVKPIRGVTRLILYNLETGEERPHEE
CHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure
MLSTDFVEHLLADAGLCVRERQTIPGRDATFAPVPATLHPRVADLLRGRFPAGLWKHQAV
CCCHHHHHHHHHHCCCEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHH
AIDRALAGESVCITTQTASGKSLIFMAVAAHRLLTEPSACVLTFYPARALIQDQLAKWRD
HHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
LLDPLGLTFGYIDGGVQVERRPDILRRHRLVLMTPDVAHAWLLPNAGETWARSFLQCLSL
HHHHHCCEEEEECCCEEECCCHHHHHCCEEEEECCCCHHEEECCCCCHHHHHHHHHHHHH
LILDEAHVYEGVFGTNFAYLIRRLLALSTLRQVLAVSATLDDPEAFLRQLTGLSVAVLGA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEC
SDDCAPVYEKTVLLAGRSPGAGLRAGRRSDDFKTVVDVVRRLAEALPTPFLAFADSRRMV
CCCCCHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EHVVAALHRQPTESAPDSDDEHDQAAPVNWMVLPYRAGYEEEDRIEIQRSLAAGSLRGVV
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
STSALELGIDIGHIDVVAMLQPPPTRKAFWQRLGRAGRSRPGLCILLDLEDRFSLGHFLE
HHHHHHCCCEECCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHH
SRSEPNCLYLENRYLQYANVLCAVAELASTGSGREALARYVEVPPDFLRLLENELEPTEP
CCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCC
VPPELAVLKQRAQASPHLEFPLRDMIDEVFDVQDRSGRRLGQVTYTQALREAYPGAVYYY
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
LAQPYRVVHFNFRAKRIEVRREKRYTTRPDLLQRAFPRWPEGLLALWKGADCGFVAESEM
ECCCEEEEEEECHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHH
QVMEKLQGFTEQRGSAREQHRYEPGSVYYQRPLLRFFETTGVAWWFPSAKLNEELARLVL
HHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHH
LSFCDLCGVQEHDVALGMFHAKQSPVQPDEVSGWCIYDSTYGSLRLTQRLGERFREVAWE
HHHHHHCCCCCCCHHEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ALERCPDDQPCEALRALAQATEGIARAPVERPSPEVSVSDEWVVVIARGEQAIYFKAEAS
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCEEEEEEECCC
EEVLIKDFRYTPRGIVYDLEPGGGWDTRRVPAEFVKPIRGVTRLILYNLETGEERPHEE
CHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]