Click here to switch to the map view.

The map label for this gene is mrpE [H]

Identifier: 221635777

GI number: 221635777

Start: 357306

End: 357779

Strand: Reverse

Name: mrpE [H]

Synonym: trd_A0371

Alternate gene names: 221635777

Gene position: 357779-357306 (Counterclockwise)

Preceding gene: 221635778

Following gene: 221635776

Centisome position: 38.98

GC content: 61.18

Gene sequence:

>474_bases
GTGACGCTGTTCCTGCTCAATCTTCTGCTCGCCCTCGTCTGGGCTATGGCAGTCGGCCGCTTCACCGTTCCCCAACTGCT
ACTCGGCTACGTGCTCGGATTTCTCGTGCTCGCCACGCTCGAGCCACTCTGGGGCACGGCACAGTACAGCGGACGCATCC
TGCGTGGGCTGCGCTTCATCGCTTTTTTCTTTGCGGAACTCCTCCTGAGTTCTCTTCAGATCGCCTACGACTCGCTCACT
CCGCGCCTGCGAGCCACTCCCCGTATCATCGCTGTCCCGCTCGATGCTGCCACCGAGACCGAGATCACGCTCTTGGCGAA
CTTTCTCACGCTCACTCCGGGGACCCTCTCACTGGACATCTCGGCCGACCGCCGAACACTTTATGTCCACGCCATGTACG
CCCGCGATCGGCAGACATTCCTGACCGAAGTGAAGCGTGGTCTGGAAGCTCGCCTCCTGGAGGTTCTGCGATGA

Upstream 100 bases:

>100_bases
CGACTCGCGCAGCAGACCAACTGCTCGATCCTCAGATCTACCAGCGAGCCGTGCTCGGCCAGCTCGGATCACCAGCACTC
GCATCGATCGGAGGTGCACC

Downstream 100 bases:

>100_bases
GCGAGCGACTGATCGGCTTTTCCGGTGTCTCTCCTCTTATCGCGCTCAGCATGCTTCTGCTCACGGTGGGACTTCTGCTC
GCCCTCGTCCGGGTAGTCCG

Product: cation antiporter

Products: NA

Alternate protein names: Mrp complex subunit E; Multiple resistance and pH homeostasis protein E [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MTLFLLNLLLALVWAMAVGRFTVPQLLLGYVLGFLVLATLEPLWGTAQYSGRILRGLRFIAFFFAELLLSSLQIAYDSLT
PRLRATPRIIAVPLDAATETEITLLANFLTLTPGTLSLDISADRRTLYVHAMYARDRQTFLTEVKRGLEARLLEVLR

Sequences:

>Translated_157_residues
MTLFLLNLLLALVWAMAVGRFTVPQLLLGYVLGFLVLATLEPLWGTAQYSGRILRGLRFIAFFFAELLLSSLQIAYDSLT
PRLRATPRIIAVPLDAATETEITLLANFLTLTPGTLSLDISADRRTLYVHAMYARDRQTFLTEVKRGLEARLLEVLR
>Mature_156_residues
TLFLLNLLLALVWAMAVGRFTVPQLLLGYVLGFLVLATLEPLWGTAQYSGRILRGLRFIAFFFAELLLSSLQIAYDSLTP
RLRATPRIIAVPLDAATETEITLLANFLTLTPGTLSLDISADRRTLYVHAMYARDRQTFLTEVKRGLEARLLEVLR

Specific function: Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance [H]

COG id: COG1863

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhE subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002758 [H]

Pfam domain/function: PF01899 MNHE [H]

EC number: NA

Molecular weight: Translated: 17641; Mature: 17510

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFLLNLLLALVWAMAVGRFTVPQLLLGYVLGFLVLATLEPLWGTAQYSGRILRGLRFI
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AFFFAELLLSSLQIAYDSLTPRLRATPRIIAVPLDAATETEITLLANFLTLTPGTLSLDI
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEE
SADRRTLYVHAMYARDRQTFLTEVKRGLEARLLEVLR
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TLFLLNLLLALVWAMAVGRFTVPQLLLGYVLGFLVLATLEPLWGTAQYSGRILRGLRFI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AFFFAELLLSSLQIAYDSLTPRLRATPRIIAVPLDAATETEITLLANFLTLTPGTLSLDI
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEE
SADRRTLYVHAMYARDRQTFLTEVKRGLEARLLEVLR
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]