Click here to switch to the map view.

The map label for this gene is ycgM [C]

Identifier: 221635478

GI number: 221635478

Start: 61352

End: 62341

Strand: Reverse

Name: ycgM [C]

Synonym: trd_A0072

Alternate gene names: 221635478

Gene position: 62341-61352 (Counterclockwise)

Preceding gene: 221635479

Following gene: 221635477

Centisome position: 6.79

GC content: 63.94

Gene sequence:

>990_bases
ATGAAGCTGGCTACCTTTGCCGTGCCGAGCCCGGCTGGTCCGGTGCGTCGGATCGGAGCGCTGGCCGAGGGCTGGCTGGT
CGACTTGCAGGCTGCTTATGCAGCCTATCTGGCCCGCACCGATCCAGGCTGCGAGGCCGAGCGACTCGCCGCTCTCCTCA
TTCCCGACGACATGGTCGCTTTTCTCGGCCACGGTCAACTGGGCTGGCAGGCCGCAGCCCAGGCTCTCGAGGAGGGCCTG
CGCATCGAGGAAGCGTTCGGTCGGCGAACACGCTATCAGCTGGGGGAAGTGCGACTGCTCGCCCCCGTGCCGCGCCCCCG
CGTCATCCGCGATTTTCTAACCTTCGAGGGCCACATGCGGAATGCCAGTCGTGCACTCGGCCGGGGTGGCGAGATTCCAC
CTGCCTGGTACGAGGTGCCGGCCTACTACAAAGGGGATCCGGACACCGTAGTCGGCCCCGATGCCGATGTCGTGATGCCG
CGCTATACCCAACAGTTCGATTTCGAGTTGGAGCTGGGTATGGTGATCGGCCGGCGTGGCAAGGATATCCCCGTCGAGGA
AGCTCATCGCTACATCGCTGGTTTCACCATCTTCAATGACTTCAGTGCGCGCGATCAGCAGATGCGCGAGGCGCCGATCG
GAATGGGGCCGAGTAAGGGGAAAGATTTCGACACGGGAAACGCGATCGGGCCCTATCTCGTCACTCCGGACGAGTTGGAC
GTGACGAACTTGCGCATGGTGGCGCGAGTCAACGGGGAAGTCTGGTCGGAAGGCTCGAGCCGCGGTATGCACTTCAGCTT
CGCCCAGCTCATCGCGCACGTCTCCCAGAGCGAGACGATCTATCCTGGTGAACTCTGGGGCTCCGGCACCGTTACCAACG
GCTGCGGACTCGAGCTGGGGCGTTACCTCCAGCCGGGCGATGTGGTCGAGCTCGAAGTCGAAGGGATCGGCATCCTGCGC
AATCGCGTCGTGCGTGCTGTCGAGGGCTGA

Upstream 100 bases:

>100_bases
GCGCATGGTATCGGCGCGAGATGGTTCGCGTTTTCGTTGCCCGCGCTCTGCGTCGTGCAGCGCAACGAGCTGGACTCTAT
CCGGGAGGGAGTGAGGAGGC

Downstream 100 bases:

>100_bases
ATCGCTGGTACGGAAGGGAAGGAGGCTGTCATGCCGTTCGTGGTCGTGGCGCACTATTACGCGAAGGAAGGGAAGGCCGA
TGAGATCGCGGCCATCCTGA

Product: fumarylacetoacetate hydrolase domain-containing protein 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKLATFAVPSPAGPVRRIGALAEGWLVDLQAAYAAYLARTDPGCEAERLAALLIPDDMVAFLGHGQLGWQAAAQALEEGL
RIEEAFGRRTRYQLGEVRLLAPVPRPRVIRDFLTFEGHMRNASRALGRGGEIPPAWYEVPAYYKGDPDTVVGPDADVVMP
RYTQQFDFELELGMVIGRRGKDIPVEEAHRYIAGFTIFNDFSARDQQMREAPIGMGPSKGKDFDTGNAIGPYLVTPDELD
VTNLRMVARVNGEVWSEGSSRGMHFSFAQLIAHVSQSETIYPGELWGSGTVTNGCGLELGRYLQPGDVVELEVEGIGILR
NRVVRAVEG

Sequences:

>Translated_329_residues
MKLATFAVPSPAGPVRRIGALAEGWLVDLQAAYAAYLARTDPGCEAERLAALLIPDDMVAFLGHGQLGWQAAAQALEEGL
RIEEAFGRRTRYQLGEVRLLAPVPRPRVIRDFLTFEGHMRNASRALGRGGEIPPAWYEVPAYYKGDPDTVVGPDADVVMP
RYTQQFDFELELGMVIGRRGKDIPVEEAHRYIAGFTIFNDFSARDQQMREAPIGMGPSKGKDFDTGNAIGPYLVTPDELD
VTNLRMVARVNGEVWSEGSSRGMHFSFAQLIAHVSQSETIYPGELWGSGTVTNGCGLELGRYLQPGDVVELEVEGIGILR
NRVVRAVEG
>Mature_329_residues
MKLATFAVPSPAGPVRRIGALAEGWLVDLQAAYAAYLARTDPGCEAERLAALLIPDDMVAFLGHGQLGWQAAAQALEEGL
RIEEAFGRRTRYQLGEVRLLAPVPRPRVIRDFLTFEGHMRNASRALGRGGEIPPAWYEVPAYYKGDPDTVVGPDADVVMP
RYTQQFDFELELGMVIGRRGKDIPVEEAHRYIAGFTIFNDFSARDQQMREAPIGMGPSKGKDFDTGNAIGPYLVTPDELD
VTNLRMVARVNGEVWSEGSSRGMHFSFAQLIAHVSQSETIYPGELWGSGTVTNGCGLELGRYLQPGDVVELEVEGIGILR
NRVVRAVEG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=275, Percent_Identity=35.6363636363636, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI40786394, Length=275, Percent_Identity=34.1818181818182, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI66348062, Length=146, Percent_Identity=30.8219178082192, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI215422413, Length=146, Percent_Identity=30.8219178082192, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI13654274, Length=145, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4557587, Length=287, Percent_Identity=26.4808362369338, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28572127, Length=233, Percent_Identity=30.9012875536481, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24663695, Length=189, Percent_Identity=28.042328042328, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571789, Length=158, Percent_Identity=25.9493670886076, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 36061; Mature: 36061

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLATFAVPSPAGPVRRIGALAEGWLVDLQAAYAAYLARTDPGCEAERLAALLIPDDMVA
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEECCHHHHH
FLGHGQLGWQAAAQALEEGLRIEEAFGRRTRYQLGEVRLLAPVPRPRVIRDFLTFEGHMR
HHCCCCCCHHHHHHHHHHCCCHHHHHCCHHHHECCCEEEECCCCCHHHHHHHHHHCCHHH
NASRALGRGGEIPPAWYEVPAYYKGDPDTVVGPDADVVMPRYTQQFDFELELGMVIGRRG
HHHHHHCCCCCCCCCCEECCCEECCCCCCEECCCCCEECCCCCCCCCEEEEEEEEECCCC
KDIPVEEAHRYIAGFTIFNDFSARDQQMREAPIGMGPSKGKDFDTGNAIGPYLVTPDELD
CCCCHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
VTNLRMVARVNGEVWSEGSSRGMHFSFAQLIAHVSQSETIYPGELWGSGTVTNGCGLELG
HHHEEEEEEECCHHCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHC
RYLQPGDVVELEVEGIGILRNRVVRAVEG
CCCCCCCEEEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKLATFAVPSPAGPVRRIGALAEGWLVDLQAAYAAYLARTDPGCEAERLAALLIPDDMVA
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEECCHHHHH
FLGHGQLGWQAAAQALEEGLRIEEAFGRRTRYQLGEVRLLAPVPRPRVIRDFLTFEGHMR
HHCCCCCCHHHHHHHHHHCCCHHHHHCCHHHHECCCEEEECCCCCHHHHHHHHHHCCHHH
NASRALGRGGEIPPAWYEVPAYYKGDPDTVVGPDADVVMPRYTQQFDFELELGMVIGRRG
HHHHHHCCCCCCCCCCEECCCEECCCCCCEECCCCCEECCCCCCCCCEEEEEEEEECCCC
KDIPVEEAHRYIAGFTIFNDFSARDQQMREAPIGMGPSKGKDFDTGNAIGPYLVTPDELD
CCCCHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
VTNLRMVARVNGEVWSEGSSRGMHFSFAQLIAHVSQSETIYPGELWGSGTVTNGCGLELG
HHHEEEEEEECCHHCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCHHHC
RYLQPGDVVELEVEGIGILRNRVVRAVEG
CCCCCCCEEEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]