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The map label for this gene is minD [H]

Identifier: 221633898

GI number: 221633898

Start: 1934855

End: 1935679

Strand: Reverse

Name: minD [H]

Synonym: trd_1925

Alternate gene names: 221633898

Gene position: 1935679-1934855 (Counterclockwise)

Preceding gene: 221633899

Following gene: 221633897

Centisome position: 96.64

GC content: 68.85

Gene sequence:

>825_bases
GTGGAGGAACAGCAGGATCGCAACGGCCGGGTCATCACCATCACCTCGGGCAAGGGTGGAGTCGGCAAGACGACCACGAC
GGCCAACGTGGGGGCGGCACTGGCCGCCCGCGGCAAAGCGGTCGTGCTGGTCGACGCCGATATCGGGTTGCGCAACCTGG
ACATTGTGCTGGGACTCGAGAATCGGATCGTCTACGACATCGTCGACGTCGTGGAGGGCCGTTGCCGACTCCGGCAAGCG
CTCATCCGCGACAAGCGGCTGACCAACCTGGCGCTCATCCCTGCCGCCCAGACCCGCGACAAGGAGGCCGTCTCGCCGGA
GCAGATGCGCGCCCTCTGCCAGGAACTGCGCCAGCAGTTCGACTTCGTCCTGATCGACTCGCCGGCGGGAATCGAGCGCG
GCTTCCGCAACGCGATCGCTGGCGCCGACGAGGTGCTCGTCGTCACCAATCCGGAAGTCTCCGCTGTCCGCGATGCCGAC
CGCATCGTCGGGCTGGTCGAGGCAGCCGAGCTCCCGCCCCCGCGGCTGATCGTCAACCGGATCGATCCGGAACTGGTCCG
GCGGGGTGACATGCTCTCCGTCGAGGACGTCCTGGAGATCCTGGCCATCCCGCTCATCGGGGTGGTGCCGGCCGACGAGA
CGATCGTCACGGCGACCAACCGGGGCGAGCCGGTCGCGCTCGATCCCCACTCGCGGGCCGGTCAGGCGTTCCGCGATATC
GCCGCGCGCTTGCTCGGCGAGGAGGTGCCGTTCCAGCCGTTGGACACACCGGATGGGGTCTGGCGACGCATGCTGCGCGC
GCTCGGCTTCGGTAGCCGCGCCTGA

Upstream 100 bases:

>100_bases
ATGCGCCAGCCTTGGCACGGGTGGTCGATGGGCAGATCGTGATCGAGCCCTGGCGGATCGAACGACGCTAGCCTGGTAGT
GCGCCAGGAGGAGGGGTGCG

Downstream 100 bases:

>100_bases
ACCAGAGGAGGGAGACTGCATGGGCTGGTTGGACGCGCTCTTCGGTCGCAGCACGAGCCGGACGCCGCGCGGCAGCGCGC
AGATCGCCAAGCAACGCCTG

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MEEQQDRNGRVITITSGKGGVGKTTTTANVGAALAARGKAVVLVDADIGLRNLDIVLGLENRIVYDIVDVVEGRCRLRQA
LIRDKRLTNLALIPAAQTRDKEAVSPEQMRALCQELRQQFDFVLIDSPAGIERGFRNAIAGADEVLVVTNPEVSAVRDAD
RIVGLVEAAELPPPRLIVNRIDPELVRRGDMLSVEDVLEILAIPLIGVVPADETIVTATNRGEPVALDPHSRAGQAFRDI
AARLLGEEVPFQPLDTPDGVWRRMLRALGFGSRA

Sequences:

>Translated_274_residues
MEEQQDRNGRVITITSGKGGVGKTTTTANVGAALAARGKAVVLVDADIGLRNLDIVLGLENRIVYDIVDVVEGRCRLRQA
LIRDKRLTNLALIPAAQTRDKEAVSPEQMRALCQELRQQFDFVLIDSPAGIERGFRNAIAGADEVLVVTNPEVSAVRDAD
RIVGLVEAAELPPPRLIVNRIDPELVRRGDMLSVEDVLEILAIPLIGVVPADETIVTATNRGEPVALDPHSRAGQAFRDI
AARLLGEEVPFQPLDTPDGVWRRMLRALGFGSRA
>Mature_274_residues
MEEQQDRNGRVITITSGKGGVGKTTTTANVGAALAARGKAVVLVDADIGLRNLDIVLGLENRIVYDIVDVVEGRCRLRQA
LIRDKRLTNLALIPAAQTRDKEAVSPEQMRALCQELRQQFDFVLIDSPAGIERGFRNAIAGADEVLVVTNPEVSAVRDAD
RIVGLVEAAELPPPRLIVNRIDPELVRRGDMLSVEDVLEILAIPLIGVVPADETIVTATNRGEPVALDPHSRAGQAFRDI
AARLLGEEVPFQPLDTPDGVWRRMLRALGFGSRA

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=266, Percent_Identity=49.6240601503759, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29713; Mature: 29713

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEQQDRNGRVITITSGKGGVGKTTTTANVGAALAARGKAVVLVDADIGLRNLDIVLGLE
CCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECC
NRIVYDIVDVVEGRCRLRQALIRDKRLTNLALIPAAQTRDKEAVSPEQMRALCQELRQQF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHC
DFVLIDSPAGIERGFRNAIAGADEVLVVTNPEVSAVRDADRIVGLVEAAELPPPRLIVNR
CEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHCC
IDPELVRRGDMLSVEDVLEILAIPLIGVVPADETIVTATNRGEPVALDPHSRAGQAFRDI
CCHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCEEEECCCHHHHHHHHHH
AARLLGEEVPFQPLDTPDGVWRRMLRALGFGSRA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEEQQDRNGRVITITSGKGGVGKTTTTANVGAALAARGKAVVLVDADIGLRNLDIVLGLE
CCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECC
NRIVYDIVDVVEGRCRLRQALIRDKRLTNLALIPAAQTRDKEAVSPEQMRALCQELRQQF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHC
DFVLIDSPAGIERGFRNAIAGADEVLVVTNPEVSAVRDADRIVGLVEAAELPPPRLIVNR
CEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHCC
IDPELVRRGDMLSVEDVLEILAIPLIGVVPADETIVTATNRGEPVALDPHSRAGQAFRDI
CCHHHHHCCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCEEEECCCHHHHHHHHHH
AARLLGEEVPFQPLDTPDGVWRRMLRALGFGSRA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]