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The map label for this gene is yqjC [H]

Identifier: 221633896

GI number: 221633896

Start: 1934040

End: 1934462

Strand: Reverse

Name: yqjC [H]

Synonym: trd_1923

Alternate gene names: 221633896

Gene position: 1934462-1934040 (Counterclockwise)

Preceding gene: 221633897

Following gene: 221633893

Centisome position: 96.58

GC content: 66.19

Gene sequence:

>423_bases
ATGGTACCCGTGCCGGTGATCGGGCTTCACCACGTCGGGATCGTCGTCGCTGACCTGGATGCAGCGATCGAGACCTACCG
GAAGCTGGGGCTCACCTTCGACGGCATCGCGGACTACCCGCACACCCGGATCGCGCTCTTCCATGGTGGCGAGGGGCACG
TCGAGCTGTTCGAGCCCAAGGACCCGGATTCCGATCTCGGACGCTTCCTCCAGCGGCGTGGCGGACTCCACCACGTGGCC
TACGCGGTGCGCGACATCCGCGCGGCCCTGCGCCAGCTCGAGGAGCAGGGCTTCCAGCTCATCCACCGCGAGCCAGTGAT
CGGCCTGCATGGCTTGCCGGTCGCCTTCATCCACCACGAGTCGTGTCACGGCGTCCTGACCGAGCTGATCGAAATCCCGG
AAGAAGGCAGCACGCGTCAGTAA

Upstream 100 bases:

>100_bases
CGCGGCGCCACGCAGTGAGTTCACTGCTATACTTCGAACCTGCTACGCACCGGACGCAGTGCGTTGCGATCGGCCGCACG
AGCGAGGGGAGTATCGGGGT

Downstream 100 bases:

>100_bases
CCGGGTCGTCGACACGGCAGCGCAGCTGATCGAAGAGAGCCAGCTGCCCGCCCAGTCGCGCCGGTCGGCCAGGCCGTGAT
GCGGGCAAAACCAGCTCCCA

Product: methylmalonyl-CoA epimerase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MVPVPVIGLHHVGIVVADLDAAIETYRKLGLTFDGIADYPHTRIALFHGGEGHVELFEPKDPDSDLGRFLQRRGGLHHVA
YAVRDIRAALRQLEEQGFQLIHREPVIGLHGLPVAFIHHESCHGVLTELIEIPEEGSTRQ

Sequences:

>Translated_140_residues
MVPVPVIGLHHVGIVVADLDAAIETYRKLGLTFDGIADYPHTRIALFHGGEGHVELFEPKDPDSDLGRFLQRRGGLHHVA
YAVRDIRAALRQLEEQGFQLIHREPVIGLHGLPVAFIHHESCHGVLTELIEIPEEGSTRQ
>Mature_140_residues
MVPVPVIGLHHVGIVVADLDAAIETYRKLGLTFDGIADYPHTRIALFHGGEGHVELFEPKDPDSDLGRFLQRRGGLHHVA
YAVRDIRAALRQLEEQGFQLIHREPVIGLHGLPVAFIHHESCHGVLTELIEIPEEGSTRQ

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=126, Percent_Identity=35.7142857142857, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17506387, Length=125, Percent_Identity=34.4, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15555; Mature: 15555

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVPVIGLHHVGIVVADLDAAIETYRKLGLTFDGIADYPHTRIALFHGGEGHVELFEPK
CCCCCEECHHHHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEECCC
DPDSDLGRFLQRRGGLHHVAYAVRDIRAALRQLEEQGFQLIHREPVIGLHGLPVAFIHHE
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
SCHGVLTELIEIPEEGSTRQ
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVPVPVIGLHHVGIVVADLDAAIETYRKLGLTFDGIADYPHTRIALFHGGEGHVELFEPK
CCCCCEECHHHHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEECCC
DPDSDLGRFLQRRGGLHHVAYAVRDIRAALRQLEEQGFQLIHREPVIGLHGLPVAFIHHE
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
SCHGVLTELIEIPEEGSTRQ
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]