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The map label for this gene is fabG [H]

Identifier: 221633879

GI number: 221633879

Start: 1914454

End: 1915164

Strand: Reverse

Name: fabG [H]

Synonym: trd_1906

Alternate gene names: 221633879

Gene position: 1915164-1914454 (Counterclockwise)

Preceding gene: 221633880

Following gene: 221633875

Centisome position: 95.61

GC content: 70.04

Gene sequence:

>711_bases
ATGACGGGCGAGGTTCCGGTCGCGCTGGTAAGCGGGGGGACTGGGCAAGTCGGATCGGTGGTGGTCCGTTTCTTCGCCGA
GCGAGGTGCGCGTCTCCTCGTGCCCTATCGCACGAGCGCACACTGGGAGCAACTCCAAGAGTCGCTCGGCTCGCTGGCCG
GCCTCGTCGACGGGCTCGCCGTCGACCTCGCCGATCCCGAGGGAGGCGAACGGGCGGTGGCTGCTGCGCTCGAACGGTTC
GGTCGTCTGGACTGGGTGCTGTGCCTGGCCGGTGGCTTCCGGCCCGGTCGTCTCGCCGAGACGGGGCAGGAGGTCTGGCA
GGAGCTGCTGGCGCTCAATCTGTGGCCGACCGTCTCCGTGCTGCGGGCGGCGCTCCCGCACCTCCTCGCACAGGGTTCCG
GGCGGATCGTCACCGTCGGTGCCCGAGCCGCGCTCGATCCTGGTCCCGGTGCCGTCGCCTATGCAGCGGTCAAGCAGGCT
GTCGTGACGTTGACGCTGGCGATCGCGCGCGAGTGCCGCGGCACCGGCGTCACGGCGAACTGCATCGCCCCGGCGACGAT
CGACACGCCCGCCAACCGCGCCGCCATGCCCACCGCCGACTTCACCAAGTGGGTCAAGCCGGAACAGGTGGCAGCGTTGC
TCTGGTATCTCTGCTCACAGGAAGGAGCTGCCCTGAATGGTGCGGTCATCCCGCTGGCCGGGGGGCAATGA

Upstream 100 bases:

>100_bases
CAAGGGTTCGCGATCGGTCGACCAGAACCACTCGCGCTCCCTTGACCTCCTCCGTACACTCAGCCTCGAGCTGTGCTCGA
GCGGACGAGAGGAGAACCAG

Downstream 100 bases:

>100_bases
GCGCGGCATCATCCCCAGGCATGGGTCGGCATATCGACGCGCGGCGTCCCATCCCAGGTGGCACCGTAGAGGTGCCAACG
GAAGGCCTCCTGGAGCGCAC

Product: putative oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTGEVPVALVSGGTGQVGSVVVRFFAERGARLLVPYRTSAHWEQLQESLGSLAGLVDGLAVDLADPEGGERAVAAALERF
GRLDWVLCLAGGFRPGRLAETGQEVWQELLALNLWPTVSVLRAALPHLLAQGSGRIVTVGARAALDPGPGAVAYAAVKQA
VVTLTLAIARECRGTGVTANCIAPATIDTPANRAAMPTADFTKWVKPEQVAALLWYLCSQEGAALNGAVIPLAGGQ

Sequences:

>Translated_236_residues
MTGEVPVALVSGGTGQVGSVVVRFFAERGARLLVPYRTSAHWEQLQESLGSLAGLVDGLAVDLADPEGGERAVAAALERF
GRLDWVLCLAGGFRPGRLAETGQEVWQELLALNLWPTVSVLRAALPHLLAQGSGRIVTVGARAALDPGPGAVAYAAVKQA
VVTLTLAIARECRGTGVTANCIAPATIDTPANRAAMPTADFTKWVKPEQVAALLWYLCSQEGAALNGAVIPLAGGQ
>Mature_235_residues
TGEVPVALVSGGTGQVGSVVVRFFAERGARLLVPYRTSAHWEQLQESLGSLAGLVDGLAVDLADPEGGERAVAAALERFG
RLDWVLCLAGGFRPGRLAETGQEVWQELLALNLWPTVSVLRAALPHLLAQGSGRIVTVGARAALDPGPGAVAYAAVKQAV
VTLTLAIARECRGTGVTANCIAPATIDTPANRAAMPTADFTKWVKPEQVAALLWYLCSQEGAALNGAVIPLAGGQ

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=27.8008298755187, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI4504505, Length=238, Percent_Identity=31.9327731092437, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI66933014, Length=226, Percent_Identity=26.1061946902655, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=27.7227722772277, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI59889578, Length=170, Percent_Identity=31.1764705882353, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI208973246, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI126723191, Length=178, Percent_Identity=28.6516853932584, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI40254992, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=160, Percent_Identity=28.75, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=24.6913580246914, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=27.6422764227642, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786812, Length=172, Percent_Identity=27.3255813953488, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082160, Length=238, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=27.9661016949153, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787820, Length=232, Percent_Identity=23.7068965517241, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=184, Percent_Identity=25.5434782608696, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789208, Length=188, Percent_Identity=26.5957446808511, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=27.710843373494, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=26.5873015873016, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=25.7028112449799, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=23.6514522821577, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=223, Percent_Identity=27.3542600896861, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=25.5725190839695, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=25.4098360655738, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=246, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554872, Length=202, Percent_Identity=29.7029702970297, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=239, Percent_Identity=24.2677824267782, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=236, Percent_Identity=26.271186440678, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=26.4462809917355, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=27.8008298755187, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI18859837, Length=241, Percent_Identity=27.3858921161826, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=24.7967479674797, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=29.4820717131474, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=24.8979591836735, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62472128, Length=139, Percent_Identity=34.5323741007194, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17647337, Length=139, Percent_Identity=34.5323741007194, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62472140, Length=139, Percent_Identity=34.5323741007194, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24456; Mature: 24325

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEVPVALVSGGTGQVGSVVVRFFAERGARLLVPYRTSAHWEQLQESLGSLAGLVDGLA
CCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHE
VDLADPEGGERAVAAALERFGRLDWVLCLAGGFRPGRLAETGQEVWQELLALNLWPTVSV
EEECCCCCCHHHHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
LRAALPHLLAQGSGRIVTVGARAALDPGPGAVAYAAVKQAVVTLTLAIARECRGTGVTAN
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
CIAPATIDTPANRAAMPTADFTKWVKPEQVAALLWYLCSQEGAALNGAVIPLAGGQ
CCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
>Mature Secondary Structure 
TGEVPVALVSGGTGQVGSVVVRFFAERGARLLVPYRTSAHWEQLQESLGSLAGLVDGLA
CCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHE
VDLADPEGGERAVAAALERFGRLDWVLCLAGGFRPGRLAETGQEVWQELLALNLWPTVSV
EEECCCCCCHHHHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
LRAALPHLLAQGSGRIVTVGARAALDPGPGAVAYAAVKQAVVTLTLAIARECRGTGVTAN
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
CIAPATIDTPANRAAMPTADFTKWVKPEQVAALLWYLCSQEGAALNGAVIPLAGGQ
CCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]