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The map label for this gene is frhD [H]

Identifier: 221633846

GI number: 221633846

Start: 1882379

End: 1882897

Strand: Reverse

Name: frhD [H]

Synonym: trd_1873

Alternate gene names: 221633846

Gene position: 1882897-1882379 (Counterclockwise)

Preceding gene: 221633847

Following gene: 221633845

Centisome position: 94.0

GC content: 61.66

Gene sequence:

>519_bases
ATGCCACGGGCCTTGATTGCCGGGATCGGGAATATCTTTTTGCGCGATGACGGGTTCGGCTCGGCGGTGCTGCAACGTTT
GCAGCGCGAGTCGCTTCCTCCCTGGGTGACGGCAATCGACTTTGGAATCAGGAGCGTGCACCTGGTCTATGAACTTCTCA
ACGACTACGATGCGATTCTCCTGGTGGACGCGACCTCACGTGGCGGTCCGCCGGGAACGCTCTATGTCCTCGACTTGGAA
CCGCAATCGCCCGACCTAGTCGGGGAAGCGATGCTCCTCGACCCACATGCCCTGACGCCGGACCGGGCGCTGCTCGCTCT
GTCTGCACTGCGCGGCCGCACCGTCCGAGTCCGATTGATCGGCTGCGAGCCAGGATCGGTCGAAGAAGGAATGGAGCTGA
CACCGCCAGTTGCCGCAGCAGTCGACCAGGCGGTTCAGCTCGTGCTCGAGCAGTTGGCAGAACTCGTCGGCACGTCTGTC
GAAGAGAAAGGAGGTTCATCATGTTGGGACGACTGGTGA

Upstream 100 bases:

>100_bases
TTACGCTCGCCGATGACCCTGATGCGGACCTTCTCCGCGCGTGGGGACGGTTTCGCTATTTCACCCTGGATGAGCTCGAG
TTTCTGTCGGGAGAGCGGGA

Downstream 100 bases:

>100_bases
GGTGGTTCTTTCTGGTGGCGATTGCCGTGCTCATTGTCCAGTCGCTCCCTGATCTCGAGCGATACCTGCGTATTCGGGAA
ATGTGAGGGCGGTCCCATGC

Product: F420-nonreducing hydrogenase

Products: NA

Alternate protein names: Putative coenzyme F420 hydrogenase-processing subunit [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPRALIAGIGNIFLRDDGFGSAVLQRLQRESLPPWVTAIDFGIRSVHLVYELLNDYDAILLVDATSRGGPPGTLYVLDLE
PQSPDLVGEAMLLDPHALTPDRALLALSALRGRTVRVRLIGCEPGSVEEGMELTPPVAAAVDQAVQLVLEQLAELVGTSV
EEKGGSSCWDDW

Sequences:

>Translated_172_residues
MPRALIAGIGNIFLRDDGFGSAVLQRLQRESLPPWVTAIDFGIRSVHLVYELLNDYDAILLVDATSRGGPPGTLYVLDLE
PQSPDLVGEAMLLDPHALTPDRALLALSALRGRTVRVRLIGCEPGSVEEGMELTPPVAAAVDQAVQLVLEQLAELVGTSV
EEKGGSSCWDDW
>Mature_171_residues
PRALIAGIGNIFLRDDGFGSAVLQRLQRESLPPWVTAIDFGIRSVHLVYELLNDYDAILLVDATSRGGPPGTLYVLDLEP
QSPDLVGEAMLLDPHALTPDRALLALSALRGRTVRVRLIGCEPGSVEEGMELTPPVAAAVDQAVQLVLEQLAELVGTSVE
EKGGSSCWDDW

Specific function: Protease Involved In The C-Terminal Processing Of Hybc, The Large Subunit Of Hydrogenase 2. Specifically Cleaves Off A 15 Amino Acid Peptide From The C Terminus Of The Precursor Of Hybc. [C]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1789367, Length=154, Percent_Identity=33.1168831168831, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004411
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 18498; Mature: 18367

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRALIAGIGNIFLRDDGFGSAVLQRLQRESLPPWVTAIDFGIRSVHLVYELLNDYDAIL
CCCHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
LVDATSRGGPPGTLYVLDLEPQSPDLVGEAMLLDPHALTPDRALLALSALRGRTVRVRLI
EEEECCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEE
GCEPGSVEEGMELTPPVAAAVDQAVQLVLEQLAELVGTSVEEKGGSSCWDDW
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRALIAGIGNIFLRDDGFGSAVLQRLQRESLPPWVTAIDFGIRSVHLVYELLNDYDAIL
CCHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
LVDATSRGGPPGTLYVLDLEPQSPDLVGEAMLLDPHALTPDRALLALSALRGRTVRVRLI
EEEECCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEEE
GCEPGSVEEGMELTPPVAAAVDQAVQLVLEQLAELVGTSVEEKGGSSCWDDW
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2207102; 9371463 [H]