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The map label for this gene is fabD [H]

Identifier: 221633598

GI number: 221633598

Start: 1616810

End: 1617793

Strand: Reverse

Name: fabD [H]

Synonym: trd_1622

Alternate gene names: 221633598

Gene position: 1617793-1616810 (Counterclockwise)

Preceding gene: 221633599

Following gene: 221633597

Centisome position: 80.77

GC content: 67.28

Gene sequence:

>984_bases
TTGTTCGCTGGGGTGCGCGTGGCGTTCGACGCGGAGGATGAGCGCATGCAGGACGCCTGGGTTTTCCCCGGACAGGGATC
CCAATGGGTGGGCATGGGTCGTGACCTGGCCAGCGAGGACGCGCTCGCTCGCGCAGTCTTCGAGGAAGCGGATGCGGTGC
TCGGCTTCCCGCTCTCCCGGATCGTCTTCGAGGGACCGGAAGAGGAGCTCGCTGCGACGCGTCATCAACAGCCAGCGCTC
CTCGCTACCAGCATCGCGTACCTGCGTGTACTCGAGGCTCGCGGGTTGCTCCCGGTACCGCGTGTCGTCGCTGGTCACTC
GCTCGGTGAATACACGGCCCTGGTGGCTGTGGGCAGCCTGACGTTGGCCGATGCCCTGCGGCTCGTCCGCCGCCGCGGTG
AACTCATGGAGACCTATGGGCGCGGTGGCATGCTCGCGGTCATCGGCCTCGACCGCGAGCGACTGGCCGCCATCGCTAGC
GAGGCCGGCGTCGAGCTCGCCAACGAGAACGCACCGAACCAACTAACGCTGAGTGGGCCGGACGAGGCCCTCGAGCGCGC
AGCCGAACTCGCCCGCGGTGCGGGTGCGCGGCGAGTCGTCCGTTTGCCGGTCAACGCTGCTTTCCATTCTCGCTGGATGC
GGCCGGTCGCCGATGCGCTCGCCCTCGAATTGGCGAATATACCGATTCGAACGCCCAGTGTGCCGCTGATCGCCTGCTCG
GACGCGCGCGTGCTCACTGATCCGGAGGATCTCCGCCGAGAGCTTGTCGAGCAGATCGCGTCACCGGTTCGTTGGGTCGC
GGTCGTGCAGCGCGCGCTCGACCTCGGCGTTGCGCATTTCTGGGAGATCGGCCCTGGCCAGGTGCTGAGCGGCTTGATCC
GGCGTATTGCACCCACTGCCGAGATCACCACAGCTGAACAGCTCCTGCGAGCGGAGGATGTCTCGCTCGTCCGACAGGAG
CGGGTGGCGAAGGAGGAGCGATGA

Upstream 100 bases:

>100_bases
CCGATCGGGTTGGCTGAGGCCGCCGACCAGGGTGTCCTGCACCCTGGGATGAACGTCGTCCTGGTCGCCTTCGGTGCTGG
ACTCGCCTGGGCTGCCAGCG

Downstream 100 bases:

>100_bases
GCGGAGAACGCGGAGCAGCGATCGTGACCGGTGCCGTTCGTGGGATCGGTCGTGCGACCGCGCTGCGGTTGGCCCGAGAC
GGCTTCAAGGTCGTCGTCAA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MFAGVRVAFDAEDERMQDAWVFPGQGSQWVGMGRDLASEDALARAVFEEADAVLGFPLSRIVFEGPEEELAATRHQQPAL
LATSIAYLRVLEARGLLPVPRVVAGHSLGEYTALVAVGSLTLADALRLVRRRGELMETYGRGGMLAVIGLDRERLAAIAS
EAGVELANENAPNQLTLSGPDEALERAAELARGAGARRVVRLPVNAAFHSRWMRPVADALALELANIPIRTPSVPLIACS
DARVLTDPEDLRRELVEQIASPVRWVAVVQRALDLGVAHFWEIGPGQVLSGLIRRIAPTAEITTAEQLLRAEDVSLVRQE
RVAKEER

Sequences:

>Translated_327_residues
MFAGVRVAFDAEDERMQDAWVFPGQGSQWVGMGRDLASEDALARAVFEEADAVLGFPLSRIVFEGPEEELAATRHQQPAL
LATSIAYLRVLEARGLLPVPRVVAGHSLGEYTALVAVGSLTLADALRLVRRRGELMETYGRGGMLAVIGLDRERLAAIAS
EAGVELANENAPNQLTLSGPDEALERAAELARGAGARRVVRLPVNAAFHSRWMRPVADALALELANIPIRTPSVPLIACS
DARVLTDPEDLRRELVEQIASPVRWVAVVQRALDLGVAHFWEIGPGQVLSGLIRRIAPTAEITTAEQLLRAEDVSLVRQE
RVAKEER
>Mature_327_residues
MFAGVRVAFDAEDERMQDAWVFPGQGSQWVGMGRDLASEDALARAVFEEADAVLGFPLSRIVFEGPEEELAATRHQQPAL
LATSIAYLRVLEARGLLPVPRVVAGHSLGEYTALVAVGSLTLADALRLVRRRGELMETYGRGGMLAVIGLDRERLAAIAS
EAGVELANENAPNQLTLSGPDEALERAAELARGAGARRVVRLPVNAAFHSRWMRPVADALALELANIPIRTPSVPLIACS
DARVLTDPEDLRRELVEQIASPVRWVAVVQRALDLGVAHFWEIGPGQVLSGLIRRIAPTAEITTAEQLLRAEDVSLVRQE
RVAKEER

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=323, Percent_Identity=31.8885448916409, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI41872631, Length=216, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787334, Length=290, Percent_Identity=43.7931034482759, Blast_Score=213, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI71984332, Length=299, Percent_Identity=31.438127090301, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=288, Percent_Identity=26.3888888888889, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24665753, Length=309, Percent_Identity=31.0679611650485, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 35505; Mature: 35505

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAGVRVAFDAEDERMQDAWVFPGQGSQWVGMGRDLASEDALARAVFEEADAVLGFPLSR
CCCCEEEEECCCHHHHHHCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
IVFEGPEEELAATRHQQPALLATSIAYLRVLEARGLLPVPRVVAGHSLGEYTALVAVGSL
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHH
TLADALRLVRRRGELMETYGRGGMLAVIGLDRERLAAIASEAGVELANENAPNQLTLSGP
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCEECCCCCCCEEEECCH
DEALERAAELARGAGARRVVRLPVNAAFHSRWMRPVADALALELANIPIRTPSVPLIACS
HHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
DARVLTDPEDLRRELVEQIASPVRWVAVVQRALDLGVAHFWEIGPGQVLSGLIRRIAPTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
EITTAEQLLRAEDVSLVRQERVAKEER
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFAGVRVAFDAEDERMQDAWVFPGQGSQWVGMGRDLASEDALARAVFEEADAVLGFPLSR
CCCCEEEEECCCHHHHHHCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
IVFEGPEEELAATRHQQPALLATSIAYLRVLEARGLLPVPRVVAGHSLGEYTALVAVGSL
HHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHH
TLADALRLVRRRGELMETYGRGGMLAVIGLDRERLAAIASEAGVELANENAPNQLTLSGP
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCEECCCCCCCEEEECCH
DEALERAAELARGAGARRVVRLPVNAAFHSRWMRPVADALALELANIPIRTPSVPLIACS
HHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
DARVLTDPEDLRRELVEQIASPVRWVAVVQRALDLGVAHFWEIGPGQVLSGLIRRIAPTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
EITTAEQLLRAEDVSLVRQERVAKEER
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]