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The map label for this gene is csd [H]

Identifier: 221633543

GI number: 221633543

Start: 1551623

End: 1552789

Strand: Reverse

Name: csd [H]

Synonym: trd_1567

Alternate gene names: 221633543

Gene position: 1552789-1551623 (Counterclockwise)

Preceding gene: 221633544

Following gene: 221633542

Centisome position: 77.52

GC content: 69.15

Gene sequence:

>1167_bases
ATGATGAGTTATTTGGACAACGCCACGACCAGCTGGCCCAAACCGGATGTCGTGCGCGAAACGCTCGCTGGCTTCCTGGC
GACGGCGAGCGGTGCTCCCGTCCGGACAGGGCACCGGCTGGCGCGGGCGACCTGGGAAGCGGTCGAGCAAGCTCGGCAGC
GACTAGCGGCGTTCCTCGGTGTGGCTGATCCGCGGCGTGTCGTCTTCACGGCCAGCGGTACCGATGCGCTCAATCTCGCG
CTCAAGGGGTTGCTGGGCCCGGGTGACCACGTGGTGACGACCGCGCTCGAGCACGATGCGGTGCGGAGACCGTTGCGGGC
ACTCGAAGTGTTCGGTGTCACCACCACGCGCGTGCCGGTCGGGGCCGATGGGACAGTCGATCCGGACGATGTGCGCCGCG
CGTTGCGCCCCAATACGCGTCTCGTCGTCGTCTGCCACGCCTCCAACGTGACGGGTGCGATCCAGCCGGTCAGCGAGATC
GTCGAGCTCGCGCATGCTCGCGGGGCCTTTGTCCTGATCGATGCAGCCCAGACGGCGGGAGTCATTCCGCTGGCCATCGA
TGCCCTGGGTGCCGATTTGGTCGCGCTCAGCGGGCACAAGTGGCTGCTCGGCCCTCCGGGAACTGGGGCGCTGGTCGTCG
GCCCGCGCATCGACCCGTCCGAGCTCGTTCCGCTGCGCGATGGGGCGACAGGAACCGAGTCGCCGGACGACGCGGGGCCG
CGCAGCCTCCCGGAGCGGTACGAGACCGGGACACTCGATACGATCGGACTGGCTGCTTTAGGGGCGGCCGTGGACTGGCT
GGCACGGACTGGCCTGGCCAGTACGGGGGAGCGCGCTCGCGTGCTCACCGAGCGACTCGTTGCCGGCCTCAGCGCTCTCC
CGGGTGTGCGGCTGTTCACGCCGGCTCAGGCCGCTTCTCGCGTCGCTCTCGTCTCGTTCCAGGTGGAGGGATGGCGACCG
CTCGACCTGGCGCGTGCGCTGGAGCGGGACTTCGCCATTCTGGTCGGGGCAGGGCTCCACGGTGCCAGCGAGGCCTGCCG
GTCCATCGGCGCGTATCCTTGTGGAACCGTCCGCCTTTCGCCTGGATGGTCGACGTCCGAGGAAGAGATCGATCGAGCCA
TCGCGGCTGTGGCAACGCTCGCGCGCGCACCGCAGTGCAAGGACTGA

Upstream 100 bases:

>100_bases
AGTTGACGGTCTTCCCGGACGGACGAGCCATCGTGCGTGGGACGACCGATCCTGCGATTGCCCGCGTGCTCTACGCGCGG
TACATCGGGATGTGACGGGG

Downstream 100 bases:

>100_bases
GGAGGCCGACCATGCCGCAGGAACGCCGCTCGTCCCGCTTGGAACAGCAGATTCTCGAGATTTTGGAGAAAGCGGAGCGC
GAGCCGTGGTGGCGACGTGC

Product: cysteine desulfurase/cysteine sulfinate desulfinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MMSYLDNATTSWPKPDVVRETLAGFLATASGAPVRTGHRLARATWEAVEQARQRLAAFLGVADPRRVVFTASGTDALNLA
LKGLLGPGDHVVTTALEHDAVRRPLRALEVFGVTTTRVPVGADGTVDPDDVRRALRPNTRLVVVCHASNVTGAIQPVSEI
VELAHARGAFVLIDAAQTAGVIPLAIDALGADLVALSGHKWLLGPPGTGALVVGPRIDPSELVPLRDGATGTESPDDAGP
RSLPERYETGTLDTIGLAALGAAVDWLARTGLASTGERARVLTERLVAGLSALPGVRLFTPAQAASRVALVSFQVEGWRP
LDLARALERDFAILVGAGLHGASEACRSIGAYPCGTVRLSPGWSTSEEEIDRAIAAVATLARAPQCKD

Sequences:

>Translated_388_residues
MMSYLDNATTSWPKPDVVRETLAGFLATASGAPVRTGHRLARATWEAVEQARQRLAAFLGVADPRRVVFTASGTDALNLA
LKGLLGPGDHVVTTALEHDAVRRPLRALEVFGVTTTRVPVGADGTVDPDDVRRALRPNTRLVVVCHASNVTGAIQPVSEI
VELAHARGAFVLIDAAQTAGVIPLAIDALGADLVALSGHKWLLGPPGTGALVVGPRIDPSELVPLRDGATGTESPDDAGP
RSLPERYETGTLDTIGLAALGAAVDWLARTGLASTGERARVLTERLVAGLSALPGVRLFTPAQAASRVALVSFQVEGWRP
LDLARALERDFAILVGAGLHGASEACRSIGAYPCGTVRLSPGWSTSEEEIDRAIAAVATLARAPQCKD
>Mature_388_residues
MMSYLDNATTSWPKPDVVRETLAGFLATASGAPVRTGHRLARATWEAVEQARQRLAAFLGVADPRRVVFTASGTDALNLA
LKGLLGPGDHVVTTALEHDAVRRPLRALEVFGVTTTRVPVGADGTVDPDDVRRALRPNTRLVVVCHASNVTGAIQPVSEI
VELAHARGAFVLIDAAQTAGVIPLAIDALGADLVALSGHKWLLGPPGTGALVVGPRIDPSELVPLRDGATGTESPDDAGP
RSLPERYETGTLDTIGLAALGAAVDWLARTGLASTGERARVLTERLVAGLSALPGVRLFTPAQAASRVALVSFQVEGWRP
LDLARALERDFAILVGAGLHGASEACRSIGAYPCGTVRLSPGWSTSEEEIDRAIAAVATLARAPQCKD

Specific function: Fe-S cluster biosynthesis [C]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=385, Percent_Identity=31.6883116883117, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI156713448, Length=321, Percent_Identity=28.6604361370716, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI48994898, Length=389, Percent_Identity=33.4190231362468, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1787970, Length=399, Percent_Identity=28.5714285714286, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789175, Length=380, Percent_Identity=28.4210526315789, Blast_Score=125, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25143064, Length=218, Percent_Identity=33.9449541284404, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17533177, Length=341, Percent_Identity=28.4457478005865, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193211090, Length=282, Percent_Identity=24.822695035461, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=390, Percent_Identity=31.2820512820513, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20129463, Length=384, Percent_Identity=34.1145833333333, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 40494; Mature: 40494

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSYLDNATTSWPKPDVVRETLAGFLATASGAPVRTGHRLARATWEAVEQARQRLAAFLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
VADPRRVVFTASGTDALNLALKGLLGPGDHVVTTALEHDAVRRPLRALEVFGVTTTRVPV
CCCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
GADGTVDPDDVRRALRPNTRLVVVCHASNVTGAIQPVSEIVELAHARGAFVLIDAAQTAG
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
VIPLAIDALGADLVALSGHKWLLGPPGTGALVVGPRIDPSELVPLRDGATGTESPDDAGP
CHHHHHHHHCCCEEEECCCEEEECCCCCCEEEECCCCCHHHCEECCCCCCCCCCCCCCCC
RSLPERYETGTLDTIGLAALGAAVDWLARTGLASTGERARVLTERLVAGLSALPGVRLFT
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEC
PAQAASRVALVSFQVEGWRPLDLARALERDFAILVGAGLHGASEACRSIGAYPCGTVRLS
CHHHHCEEEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCCEEEEC
PGWSTSEEEIDRAIAAVATLARAPQCKD
CCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMSYLDNATTSWPKPDVVRETLAGFLATASGAPVRTGHRLARATWEAVEQARQRLAAFLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
VADPRRVVFTASGTDALNLALKGLLGPGDHVVTTALEHDAVRRPLRALEVFGVTTTRVPV
CCCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
GADGTVDPDDVRRALRPNTRLVVVCHASNVTGAIQPVSEIVELAHARGAFVLIDAAQTAG
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCC
VIPLAIDALGADLVALSGHKWLLGPPGTGALVVGPRIDPSELVPLRDGATGTESPDDAGP
CHHHHHHHHCCCEEEECCCEEEECCCCCCEEEECCCCCHHHCEECCCCCCCCCCCCCCCC
RSLPERYETGTLDTIGLAALGAAVDWLARTGLASTGERARVLTERLVAGLSALPGVRLFT
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEC
PAQAASRVALVSFQVEGWRPLDLARALERDFAILVGAGLHGASEACRSIGAYPCGTVRLS
CHHHHCEEEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCCEEEEC
PGWSTSEEEIDRAIAAVATLARAPQCKD
CCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]