| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is hemG [H]
Identifier: 221633362
GI number: 221633362
Start: 1371700
End: 1373094
Strand: Reverse
Name: hemG [H]
Synonym: trd_1381
Alternate gene names: 221633362
Gene position: 1373094-1371700 (Counterclockwise)
Preceding gene: 221633363
Following gene: 221633360
Centisome position: 68.55
GC content: 67.96
Gene sequence:
>1395_bases GTGGTCGTCATCGGCGGGGGGATCGCTGGTCTCGCTGCGGCCTGGCGCCTCGAACAGCTGAGTCCGGCGATCAGCGTCAC GCTGATCGAGGCAGAGCCCCGCCTGGGGGGATGGATCCGGACCGAGCACTGGGGTGAGGTCATCATCGAGCATGGTCCGG ATTCGTGGGTGGCGAGCAAACCTGCAGCGACTGAACTCGCCCGTGCACTCGGTCTGGAGTCGGAGATCATCGGCTTGCGA GCGGATCAGGCCGAGACGTCGATCATGCACGACGGGCGCCTGCTCCCACTCCCCAGTGGGCTCTCCCTCCTGGTCCCGAC ACGCCTTCGACCGTTGCTCACGAGCCCGCTCCTCTCGCCACTCGGGAAGTTGCGGCTTCTCGCTGAGTATCTCGTTCCAC CCCGGCTCGATGAAGACGACGAATCGCTGGCGAGCTTCGTACGCCGCCGCTTCGGTCGCGAGTTCGCCGAGCGTGTGGCC GAGCCGCTCCTTTCGGGGATCTTCGCTGGAGACGCGGGGCAGCTGAGCGTTCTCGCAACCTATCCGCAGTTGCGGCGCCT GGAGCGGGAGCGAGGCAGTCTGTTGCGCGCGAGAGCCATGCAGGCGCGACGACCAGCTGGGCTAGCCGGAGGATCACCCT TTCTGACCCTGCGGTCTGGTATGGGACGTCTCGTGAGGGCGGTCGCTGGCGATTTGCAGCGCACCGTGGTGCGAACCGGT GCGACCGCGTTGGGCATTGCGCCTTCCAATGGTGGATTCGCGATCGACCTGGCGGACGGGACGCGGCTGGAGGCTGATGG GGTGATCCTCGCGGTACCGGCCTGGCGGGCAGCCCGGCTGTTCGAGCGATCCTTTACCCGAGCCGCAGCGGTCCTGCAGG CTCTTCCGTATGCCTCCAGCGCGGCGGTCACGCTGGTCTACCGCCAGAGTGATCTCGCTGGATTCGCGCGGGGGCGAGGC TTCCTGGTTCCCGCGCGCGAGGGGCGGCCGATCTCGGCGGTGACGTGGGTGACCAACAAGTTCCCGGCGCGCGCACCCGA ACATCTCGGGCTCGTCCGTGTCTTCTTCCGCGCCGAGCGAGCTGGGCTCAGCGACGATGCTCCCGCTGAGATCCCCGTCG CGGTCGCGCTTCAGGAACTCCGCTCCGCAGTCGGTTTGCAAGCCGAACCCCTACATGCGATCGTCTCCCGGCACGAGCGA GCATTGCCACAGTATTGCGTCGGACATCGGCAGCGGGTCGCCGAACTCCGGAGTCTCCTGGGTTCCTGGCCGGGGCTCGC GCTGGCCGGCGCAGCCTATGACGGTGTGGGCGTATCGGACTGCATCGCGAGTGGCTGGCGGGCAGCCGAGGCGGTCCTGC AGGGGATCGGAGCGAGGCAGAGCGTGGGGCGCTAG
Upstream 100 bases:
>100_bases TGAACGATCATCCCCTGCTTTGCCGAGCGATCGCGAATGCGGTGCGGCGGACGCTGCGCGCGGCGCGCGTTGGGGTAGGA TGAGCGAGGTGCACGCTCAT
Downstream 100 bases:
>100_bases AAACCGACCCACGCGCGGACGCGCTCGAGCAGCGTCATTGAAGTAGAGAGCATGTCAGGATCCGGAGAGGGCGACGCGAC GTCCTGGTCCCGCACGACAG
Product: protoporphyrinogen oxidase
Products: NA
Alternate protein names: PPO [H]
Number of amino acids: Translated: 464; Mature: 464
Protein sequence:
>464_residues MVVIGGGIAGLAAAWRLEQLSPAISVTLIEAEPRLGGWIRTEHWGEVIIEHGPDSWVASKPAATELARALGLESEIIGLR ADQAETSIMHDGRLLPLPSGLSLLVPTRLRPLLTSPLLSPLGKLRLLAEYLVPPRLDEDDESLASFVRRRFGREFAERVA EPLLSGIFAGDAGQLSVLATYPQLRRLERERGSLLRARAMQARRPAGLAGGSPFLTLRSGMGRLVRAVAGDLQRTVVRTG ATALGIAPSNGGFAIDLADGTRLEADGVILAVPAWRAARLFERSFTRAAAVLQALPYASSAAVTLVYRQSDLAGFARGRG FLVPAREGRPISAVTWVTNKFPARAPEHLGLVRVFFRAERAGLSDDAPAEIPVAVALQELRSAVGLQAEPLHAIVSRHER ALPQYCVGHRQRVAELRSLLGSWPGLALAGAAYDGVGVSDCIASGWRAAEAVLQGIGARQSVGR
Sequences:
>Translated_464_residues MVVIGGGIAGLAAAWRLEQLSPAISVTLIEAEPRLGGWIRTEHWGEVIIEHGPDSWVASKPAATELARALGLESEIIGLR ADQAETSIMHDGRLLPLPSGLSLLVPTRLRPLLTSPLLSPLGKLRLLAEYLVPPRLDEDDESLASFVRRRFGREFAERVA EPLLSGIFAGDAGQLSVLATYPQLRRLERERGSLLRARAMQARRPAGLAGGSPFLTLRSGMGRLVRAVAGDLQRTVVRTG ATALGIAPSNGGFAIDLADGTRLEADGVILAVPAWRAARLFERSFTRAAAVLQALPYASSAAVTLVYRQSDLAGFARGRG FLVPAREGRPISAVTWVTNKFPARAPEHLGLVRVFFRAERAGLSDDAPAEIPVAVALQELRSAVGLQAEPLHAIVSRHER ALPQYCVGHRQRVAELRSLLGSWPGLALAGAAYDGVGVSDCIASGWRAAEAVLQGIGARQSVGR >Mature_464_residues MVVIGGGIAGLAAAWRLEQLSPAISVTLIEAEPRLGGWIRTEHWGEVIIEHGPDSWVASKPAATELARALGLESEIIGLR ADQAETSIMHDGRLLPLPSGLSLLVPTRLRPLLTSPLLSPLGKLRLLAEYLVPPRLDEDDESLASFVRRRFGREFAERVA EPLLSGIFAGDAGQLSVLATYPQLRRLERERGSLLRARAMQARRPAGLAGGSPFLTLRSGMGRLVRAVAGDLQRTVVRTG ATALGIAPSNGGFAIDLADGTRLEADGVILAVPAWRAARLFERSFTRAAAVLQALPYASSAAVTLVYRQSDLAGFARGRG FLVPAREGRPISAVTWVTNKFPARAPEHLGLVRVFFRAERAGLSDDAPAEIPVAVALQELRSAVGLQAEPLHAIVSRHER ALPQYCVGHRQRVAELRSLLGSWPGLALAGAAYDGVGVSDCIASGWRAAEAVLQGIGARQSVGR
Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III [H]
COG id: COG1232
COG function: function code H; Protoporphyrinogen oxidase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the protoporphyrinogen oxidase family [H]
Homologues:
Organism=Homo sapiens, GI170650615, Length=488, Percent_Identity=33.4016393442623, Blast_Score=157, Evalue=2e-38, Organism=Homo sapiens, GI4506001, Length=488, Percent_Identity=33.4016393442623, Blast_Score=157, Evalue=2e-38, Organism=Drosophila melanogaster, GI24649745, Length=459, Percent_Identity=26.3616557734205, Blast_Score=130, Evalue=3e-30,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002937 - InterPro: IPR016040 - InterPro: IPR004572 [H]
Pfam domain/function: PF01593 Amino_oxidase [H]
EC number: =1.3.3.4 [H]
Molecular weight: Translated: 49506; Mature: 49506
Theoretical pI: Translated: 10.54; Mature: 10.54
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 1.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVVIGGGIAGLAAAWRLEQLSPAISVTLIEAEPRLGGWIRTEHWGEVIIEHGPDSWVASK CEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEECCCCCCEEEECCCCCCCCCC PAATELARALGLESEIIGLRADQAETSIMHDGRLLPLPSGLSLLVPTRLRPLLTSPLLSP CHHHHHHHHHCCCHHHEEEECCCHHHHHHCCCEEEECCCCCCEECCHHHHHHHHHHHHHH LGKLRLLAEYLVPPRLDEDDESLASFVRRRFGREFAERVAEPLLSGIFAGDAGQLSVLAT HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC YPQLRRLERERGSLLRARAMQARRPAGLAGGSPFLTLRSGMGRLVRAVAGDLQRTVVRTG CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC ATALGIAPSNGGFAIDLADGTRLEADGVILAVPAWRAARLFERSFTRAAAVLQALPYASS CCEEEEEECCCCEEEEECCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCC AAVTLVYRQSDLAGFARGRGFLVPAREGRPISAVTWVTNKFPARAPEHLGLVRVFFRAER CEEEEEEECCCHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH AGLSDDAPAEIPVAVALQELRSAVGLQAEPLHAIVSRHERALPQYCVGHRQRVAELRSLL CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH GSWPGLALAGAAYDGVGVSDCIASGWRAAEAVLQGIGARQSVGR CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCC >Mature Secondary Structure MVVIGGGIAGLAAAWRLEQLSPAISVTLIEAEPRLGGWIRTEHWGEVIIEHGPDSWVASK CEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEECCCCCCEEEECCCCCCCCCC PAATELARALGLESEIIGLRADQAETSIMHDGRLLPLPSGLSLLVPTRLRPLLTSPLLSP CHHHHHHHHHCCCHHHEEEECCCHHHHHHCCCEEEECCCCCCEECCHHHHHHHHHHHHHH LGKLRLLAEYLVPPRLDEDDESLASFVRRRFGREFAERVAEPLLSGIFAGDAGQLSVLAT HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC YPQLRRLERERGSLLRARAMQARRPAGLAGGSPFLTLRSGMGRLVRAVAGDLQRTVVRTG CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC ATALGIAPSNGGFAIDLADGTRLEADGVILAVPAWRAARLFERSFTRAAAVLQALPYASS CCEEEEEECCCCEEEEECCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCC AAVTLVYRQSDLAGFARGRGFLVPAREGRPISAVTWVTNKFPARAPEHLGLVRVFFRAER CEEEEEEECCCHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH AGLSDDAPAEIPVAVALQELRSAVGLQAEPLHAIVSRHERALPQYCVGHRQRVAELRSLL CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH GSWPGLALAGAAYDGVGVSDCIASGWRAAEAVLQGIGARQSVGR CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1459957; 9579061; 9384377; 8288631 [H]