Click here to switch to the map view.

The map label for this gene is mer [H]

Identifier: 221633335

GI number: 221633335

Start: 1347301

End: 1348338

Strand: Reverse

Name: mer [H]

Synonym: trd_1355

Alternate gene names: 221633335

Gene position: 1348338-1347301 (Counterclockwise)

Preceding gene: 221633336

Following gene: 221633332

Centisome position: 67.32

GC content: 63.87

Gene sequence:

>1038_bases
ATGACAGTGCTCGAGCGACGCGACGATCCGGTAAACGCGTTCCGGCGCGAGTTGGCCGTCATCCCACGACTGGTCGGGTG
GATACGGGGAAGCGGTGTGCATGGGGAATGGAAGGTACCGACGGTGCGTGAGCGAACGAGCTTGGCCTTCGGACTGAACA
TCGACCCAGTCATCGATCGTCCATGGGAAATCGAAGCACTGGCCCAACTCGCAGATACCGCTGGCATCGCCCTGGTGGCG
ATGCAAGATCACGCCTACAACCCACGCTTCGCTGAGACGTGGACAGTCCTGACAGCCGTTGCGCTTCGGACCCAGCGCGT
CCATGTTCTGATGAATGTGGCCACACTCGCTCTCCGTCCAGCGCCGATGCTGGCAAAAGCAGCAGCGACCCTCGACCGCT
TGACCGGAGGGCGGGTCGAGTTGGGATTAGGATCCGGTGGAATTTGGGACGGCATCGCCGCGATGGGAGGACCCCGTTGG
TCGCCGGGTGAGGCGCTCGCAGCGATCGAGGATGCGTTGCGACTCTGCCGACTCCTGTGGGAGAGGGCAAAGAGCGGCGA
GCCGGTCACCTACGAGGGCCCTATTTTTCGCGTCGATCATCTCGTGTTCGGGCCCGCCCCGACTCGCCCGATCCCGCTCT
GGGTCGGTGCGATCAAACCGCGAGCGCTCCGACTCGCCGGTGAGCTGGCCGATGGCATCACTGTCTCGACACCCTATGTT
CTCCCGGAAAAGTTACCGCAGGTGAACCAGTGGGTGAACGAAGGTGCCGAACGAGTTGGTCGCGACCCTGCCACCATCCG
TCGGCTCTATAACCTGCTCGGGGTGCTCGACGTTCCCGGAGGCCGTTCCTATCGCGTGAACCGGCCCGGACTGCTCGGTG
GGCCAGCTGATGCCTGGGCAGACGCCATCGCGCGTTTCGCTGAACTCGGTATGGACACGTTCGTCTTTTGGCCGGTAGCC
GGCGATTATCTGGCCCAGGCTCGCCACTTCGTCGAGGAGGTGATCCCGCGCGTGCGGGATCGGGTCGGGTCCCCGTGA

Upstream 100 bases:

>100_bases
CCTCAGCGCGCCGCGACTGGAGAGACTATGCGCTGCCTGTATCTCCAACGTTCGCTCCGAGCGCGTTCTCCAGTCCGATC
CGAAGCCTGCAGCCGACTGC

Downstream 100 bases:

>100_bases
GTTGCGGCGCACCGTTGCAGCGTGCTCACTCGAGGTCGACCCACAGGAATGCTTCGGCGAGTTCCAACCCCGCTGGTGCG
CCTGCCTCGCGGGCGCGCAT

Product: putative oxidoreductase

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTVLERRDDPVNAFRRELAVIPRLVGWIRGSGVHGEWKVPTVRERTSLAFGLNIDPVIDRPWEIEALAQLADTAGIALVA
MQDHAYNPRFAETWTVLTAVALRTQRVHVLMNVATLALRPAPMLAKAAATLDRLTGGRVELGLGSGGIWDGIAAMGGPRW
SPGEALAAIEDALRLCRLLWERAKSGEPVTYEGPIFRVDHLVFGPAPTRPIPLWVGAIKPRALRLAGELADGITVSTPYV
LPEKLPQVNQWVNEGAERVGRDPATIRRLYNLLGVLDVPGGRSYRVNRPGLLGGPADAWADAIARFAELGMDTFVFWPVA
GDYLAQARHFVEEVIPRVRDRVGSP

Sequences:

>Translated_345_residues
MTVLERRDDPVNAFRRELAVIPRLVGWIRGSGVHGEWKVPTVRERTSLAFGLNIDPVIDRPWEIEALAQLADTAGIALVA
MQDHAYNPRFAETWTVLTAVALRTQRVHVLMNVATLALRPAPMLAKAAATLDRLTGGRVELGLGSGGIWDGIAAMGGPRW
SPGEALAAIEDALRLCRLLWERAKSGEPVTYEGPIFRVDHLVFGPAPTRPIPLWVGAIKPRALRLAGELADGITVSTPYV
LPEKLPQVNQWVNEGAERVGRDPATIRRLYNLLGVLDVPGGRSYRVNRPGLLGGPADAWADAIARFAELGMDTFVFWPVA
GDYLAQARHFVEEVIPRVRDRVGSP
>Mature_344_residues
TVLERRDDPVNAFRRELAVIPRLVGWIRGSGVHGEWKVPTVRERTSLAFGLNIDPVIDRPWEIEALAQLADTAGIALVAM
QDHAYNPRFAETWTVLTAVALRTQRVHVLMNVATLALRPAPMLAKAAATLDRLTGGRVELGLGSGGIWDGIAAMGGPRWS
PGEALAAIEDALRLCRLLWERAKSGEPVTYEGPIFRVDHLVFGPAPTRPIPLWVGAIKPRALRLAGELADGITVSTPYVL
PEKLPQVNQWVNEGAERVGRDPATIRRLYNLLGVLDVPGGRSYRVNRPGLLGGPADAWADAIARFAELGMDTFVFWPVAG
DYLAQARHFVEEVIPRVRDRVGSP

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 37748; Mature: 37617

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLERRDDPVNAFRRELAVIPRLVGWIRGSGVHGEWKVPTVRERTSLAFGLNIDPVIDR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEECCCCCCCCCC
PWEIEALAQLADTAGIALVAMQDHAYNPRFAETWTVLTAVALRTQRVHVLMNVATLALRP
CCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APMLAKAAATLDRLTGGRVELGLGSGGIWDGIAAMGGPRWSPGEALAAIEDALRLCRLLW
CHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
ERAKSGEPVTYEGPIFRVDHLVFGPAPTRPIPLWVGAIKPRALRLAGELADGITVSTPYV
HHHCCCCCEEECCCEEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHCCEEECCCCC
LPEKLPQVNQWVNEGAERVGRDPATIRRLYNLLGVLDVPGGRSYRVNRPGLLGGPADAWA
CHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCHHHHH
DAIARFAELGMDTFVFWPVAGDYLAQARHFVEEVIPRVRDRVGSP
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVLERRDDPVNAFRRELAVIPRLVGWIRGSGVHGEWKVPTVRERTSLAFGLNIDPVIDR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEEECCCCCCCCCC
PWEIEALAQLADTAGIALVAMQDHAYNPRFAETWTVLTAVALRTQRVHVLMNVATLALRP
CCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APMLAKAAATLDRLTGGRVELGLGSGGIWDGIAAMGGPRWSPGEALAAIEDALRLCRLLW
CHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
ERAKSGEPVTYEGPIFRVDHLVFGPAPTRPIPLWVGAIKPRALRLAGELADGITVSTPYV
HHHCCCCCEEECCCEEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHCCEEECCCCC
LPEKLPQVNQWVNEGAERVGRDPATIRRLYNLLGVLDVPGGRSYRVNRPGLLGGPADAWA
CHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCHHHHH
DAIARFAELGMDTFVFWPVAGDYLAQARHFVEEVIPRVRDRVGSP
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]