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The map label for this gene is mer [H]

Identifier: 221633325

GI number: 221633325

Start: 1336934

End: 1337869

Strand: Reverse

Name: mer [H]

Synonym: trd_1345

Alternate gene names: 221633325

Gene position: 1337869-1336934 (Counterclockwise)

Preceding gene: 221633327

Following gene: 221633320

Centisome position: 66.79

GC content: 64.0

Gene sequence:

>936_bases
ATGACCAGTGCGATGCGCAACCGACCGCTGCGGATCGGCATTCTGGTCCCCCAAGGGGAGTATCGCTGGAATGGGCGTCT
TCCGCGCTGGAGCGATCTCGAGGCGATGGCACGCCTCGCCGAGGAGATCGGGCTCGACTCGCTCTGGGTCGTGGATCATC
TTCTTTACCGCACACCGGACGGTGAACCAGAAGGGATCTGGGAATGCTGGTCGCTCCTTTCCGCCTTCGCCGCGGTCACG
AAGCGGATCACGCTGGGAACGCTCGTTCTCTGTACCAACTGGCGCAATCCGGCACTGATCGCCAAGATGGCGGAAACGGT
CAACGAGATTTCGGGAGGGCGATTGATCCTCGGGTTGGGAGCCGGGAACACGGAGCAGGAATTTCGCCGCTTCGGTTTTC
CCTGGGAGCGACGTGTCAGTCGGTTCGCCGAAGCGCTGGCGATCGTCCACGGTCTACTGCGCAACGGTTGGATCGACTAC
GCGGGTGAATTCTACACAGTGCGCGATTGCTTGCTGCGACCGCGCGGCCCACGCTCGCAGGGGCCGCCCATCCTGGTCGG
CGGGAACGGTCCGCGGGTTCTCCGGCTGGCTGCCCAATATGCCGATATCTGGAATACCTACTACGACTTCACCGGAAACC
GAGCGAGCGGGCTCGGGCCGCAGATCGAGGCGTTTCGAGCGGCCTGTCGGGATGTCGGGCGGGACTGGTCGAGCGTGACG
CTCTCGGCCTCAGCGTTGGTCGCCTTTCCCGGCCACGGGCGTATCTATGGTGTGGTCGCTGATCCGGTGCGCGGGACGCC
GGAGGAGATCGCCGAGGAGTTTCGGGCGTACGCTCGTGCGGGGATCCAACATCTGCAGCTGCGGATCGAGCCGAATACGC
TGGAGGGGCTGGAGCAGCTGGGTCGTGTTTTGGAAGTGCTCGATCGCGCTGAGTGA

Upstream 100 bases:

>100_bases
CGCAGCGGGCCCTTTCTTGCCTGTCTGGTTGCGCTCTGCCCGCGAACGCGCGAAAAACGATCTCGGATGGAGCGTGGCCG
AGTGCGAGGAGGGATGGCGA

Downstream 100 bases:

>100_bases
ATCGCCCGGACTAGTGCGCCTGCTCACCTGGTGTGCCAGCTGACCGGTGACCGCGCGGTCGTGCTCGTACGTCCGCCCGA
CGGGTCGATTATCCTATCGC

Product: putative dehydrogenase

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTSAMRNRPLRIGILVPQGEYRWNGRLPRWSDLEAMARLAEEIGLDSLWVVDHLLYRTPDGEPEGIWECWSLLSAFAAVT
KRITLGTLVLCTNWRNPALIAKMAETVNEISGGRLILGLGAGNTEQEFRRFGFPWERRVSRFAEALAIVHGLLRNGWIDY
AGEFYTVRDCLLRPRGPRSQGPPILVGGNGPRVLRLAAQYADIWNTYYDFTGNRASGLGPQIEAFRAACRDVGRDWSSVT
LSASALVAFPGHGRIYGVVADPVRGTPEEIAEEFRAYARAGIQHLQLRIEPNTLEGLEQLGRVLEVLDRAE

Sequences:

>Translated_311_residues
MTSAMRNRPLRIGILVPQGEYRWNGRLPRWSDLEAMARLAEEIGLDSLWVVDHLLYRTPDGEPEGIWECWSLLSAFAAVT
KRITLGTLVLCTNWRNPALIAKMAETVNEISGGRLILGLGAGNTEQEFRRFGFPWERRVSRFAEALAIVHGLLRNGWIDY
AGEFYTVRDCLLRPRGPRSQGPPILVGGNGPRVLRLAAQYADIWNTYYDFTGNRASGLGPQIEAFRAACRDVGRDWSSVT
LSASALVAFPGHGRIYGVVADPVRGTPEEIAEEFRAYARAGIQHLQLRIEPNTLEGLEQLGRVLEVLDRAE
>Mature_310_residues
TSAMRNRPLRIGILVPQGEYRWNGRLPRWSDLEAMARLAEEIGLDSLWVVDHLLYRTPDGEPEGIWECWSLLSAFAAVTK
RITLGTLVLCTNWRNPALIAKMAETVNEISGGRLILGLGAGNTEQEFRRFGFPWERRVSRFAEALAIVHGLLRNGWIDYA
GEFYTVRDCLLRPRGPRSQGPPILVGGNGPRVLRLAAQYADIWNTYYDFTGNRASGLGPQIEAFRAACRDVGRDWSSVTL
SASALVAFPGHGRIYGVVADPVRGTPEEIAEEFRAYARAGIQHLQLRIEPNTLEGLEQLGRVLEVLDRAE

Specific function: Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

Organism=Escherichia coli, GI1787247, Length=251, Percent_Identity=27.4900398406374, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 34742; Mature: 34611

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAMRNRPLRIGILVPQGEYRWNGRLPRWSDLEAMARLAEEIGLDSLWVVDHLLYRTPD
CCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCC
GEPEGIWECWSLLSAFAAVTKRITLGTLVLCTNWRNPALIAKMAETVNEISGGRLILGLG
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEC
AGNTEQEFRRFGFPWERRVSRFAEALAIVHGLLRNGWIDYAGEFYTVRDCLLRPRGPRSQ
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHCCCCCCCC
GPPILVGGNGPRVLRLAAQYADIWNTYYDFTGNRASGLGPQIEAFRAACRDVGRDWSSVT
CCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
LSASALVAFPGHGRIYGVVADPVRGTPEEIAEEFRAYARAGIQHLQLRIEPNTLEGLEQL
EECEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHH
GRVLEVLDRAE
HHHHHHHHCCC
>Mature Secondary Structure 
TSAMRNRPLRIGILVPQGEYRWNGRLPRWSDLEAMARLAEEIGLDSLWVVDHLLYRTPD
CCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCC
GEPEGIWECWSLLSAFAAVTKRITLGTLVLCTNWRNPALIAKMAETVNEISGGRLILGLG
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEC
AGNTEQEFRRFGFPWERRVSRFAEALAIVHGLLRNGWIDYAGEFYTVRDCLLRPRGPRSQ
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHCCCCCCCC
GPPILVGGNGPRVLRLAAQYADIWNTYYDFTGNRASGLGPQIEAFRAACRDVGRDWSSVT
CCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
LSASALVAFPGHGRIYGVVADPVRGTPEEIAEEFRAYARAGIQHLQLRIEPNTLEGLEQL
EECEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHH
GRVLEVLDRAE
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]