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The map label for this gene is acdA [H]

Identifier: 221633320

GI number: 221633320

Start: 1331617

End: 1332843

Strand: Reverse

Name: acdA [H]

Synonym: trd_1340

Alternate gene names: 221633320

Gene position: 1332843-1331617 (Counterclockwise)

Preceding gene: 221633325

Following gene: 221633319

Centisome position: 66.54

GC content: 62.67

Gene sequence:

>1227_bases
ATGCCTGAATACACCGGTGGTGGAGCGATGTTGGCGAGCAGGGAGGCGAGCGTGGACTTCTCTCTCACGGCTGAGCAGCG
TGAACTCCAGGAGCGAGCCCGGCGATTCGCGGAAACGGTCGTGAAGCCAGTAGCAACCTATTACGACCAGGAGGAGCGAC
ATCCGCACGAGTTGATCGTGCGCGCTCGCGCTGAGGGGTTGACCGAAATCACGATTCCGCGTGAGTACGGCGGGCGCGGC
CTTGGCGTGTTGGAACTCGTCCTCGTCGCTGAGCAACTGGCCTGGGCATGTGCCGGATTCACCGCTGCAGCCTGCTCGAG
TTGCCTGGCAGGCGAGCCGATCGTCATCGCGGGAAGCGAGGAACAGAAGCGACGATGGCTCCCGCGCTTGGCGGCGGGTG
AGTATGCGAGCTTCGCCTTGACCGAGCCGGACGCGGGTTCCGATGTCGCAGCGCTCGCTACCCGCGCAGAGCGATGCGGT
GATGTGTATGTCCTCAATGGTCACAAGCGGTGGATCGGCAATGCACCAATCGCGAGTTTCTTCGTGGTTTTCGCGAAGAC
CGATCCGCAAGCCGGGCACAACGGCATCAGCGTCTTCGTCGTGGAGCGCGAGTCGACAGGCATCGTCACGCGACCACTCC
GCAAGCTGGGGCAGCGGGCGATCTCCAATGGGGAAATCGAGTTCCACGACGTCGTTGTCCCAGCCAACCAACGGATCGGT
CGCGAAGGTGAAGGGTTCGCGATCGCGATGCAGACGCTGCGCCGAACGCGCCCTATGGTCGCAGCGTTCGGTGCAGGGAT
CATTCGACGCTGCCTCGACGAGTCGCTGGCTTATGCACAGCAGCGGCGCACGATGGGACAACCGATCATCCGCCACCAGG
CCATCGGCCACAAGTTAGCCGACATGCAGATTCGTTTGGAGGCTGCGCGGCAGCTGACCTATCTGGCTGCCTGGCTGGCG
GATCAGGGGGAGGACAACACGATGGCAGCTGCCGTCGCCAAGGCGTTCGCTGCCGATAGCGCGATGTGGGCGGCGACCGA
AGCGGTACAGGTGTTCGGTGGAAACGGTTACAGTCCTGACTACCCGGTCGAGAAACTGTTCCGCGATGCCAAGCTCTTGC
AAATCTACGAGGGGACCAGCGAGATTCAACGCAATATCATCGTGCGCGAACTCGTTCGCCGGTCTCGCGGGAAGGATCGG
CGTCCAGGAGAAGAACCCCTCGAGTGA

Upstream 100 bases:

>100_bases
CTCGTATCCTATCCTGTTTGCTGGGTAGAGTGGGACGCCTGAGCTGCCTCGGGGCTGTACCAACCGCGGTAACGGGACCT
CTGGACAAGATCCTCGGTTC

Downstream 100 bases:

>100_bases
GCGGAGCAGTCGCCCGCGGCGCCTGATCGCTCGTGATCGGTAGGTTGCCCGCAGCGCAAGTATGAAGACACCATTTCGAT
CGGCACAGCTTGCTGCCGGG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MPEYTGGGAMLASREASVDFSLTAEQRELQERARRFAETVVKPVATYYDQEERHPHELIVRARAEGLTEITIPREYGGRG
LGVLELVLVAEQLAWACAGFTAAACSSCLAGEPIVIAGSEEQKRRWLPRLAAGEYASFALTEPDAGSDVAALATRAERCG
DVYVLNGHKRWIGNAPIASFFVVFAKTDPQAGHNGISVFVVERESTGIVTRPLRKLGQRAISNGEIEFHDVVVPANQRIG
REGEGFAIAMQTLRRTRPMVAAFGAGIIRRCLDESLAYAQQRRTMGQPIIRHQAIGHKLADMQIRLEAARQLTYLAAWLA
DQGEDNTMAAAVAKAFAADSAMWAATEAVQVFGGNGYSPDYPVEKLFRDAKLLQIYEGTSEIQRNIIVRELVRRSRGKDR
RPGEEPLE

Sequences:

>Translated_408_residues
MPEYTGGGAMLASREASVDFSLTAEQRELQERARRFAETVVKPVATYYDQEERHPHELIVRARAEGLTEITIPREYGGRG
LGVLELVLVAEQLAWACAGFTAAACSSCLAGEPIVIAGSEEQKRRWLPRLAAGEYASFALTEPDAGSDVAALATRAERCG
DVYVLNGHKRWIGNAPIASFFVVFAKTDPQAGHNGISVFVVERESTGIVTRPLRKLGQRAISNGEIEFHDVVVPANQRIG
REGEGFAIAMQTLRRTRPMVAAFGAGIIRRCLDESLAYAQQRRTMGQPIIRHQAIGHKLADMQIRLEAARQLTYLAAWLA
DQGEDNTMAAAVAKAFAADSAMWAATEAVQVFGGNGYSPDYPVEKLFRDAKLLQIYEGTSEIQRNIIVRELVRRSRGKDR
RPGEEPLE
>Mature_407_residues
PEYTGGGAMLASREASVDFSLTAEQRELQERARRFAETVVKPVATYYDQEERHPHELIVRARAEGLTEITIPREYGGRGL
GVLELVLVAEQLAWACAGFTAAACSSCLAGEPIVIAGSEEQKRRWLPRLAAGEYASFALTEPDAGSDVAALATRAERCGD
VYVLNGHKRWIGNAPIASFFVVFAKTDPQAGHNGISVFVVERESTGIVTRPLRKLGQRAISNGEIEFHDVVVPANQRIGR
EGEGFAIAMQTLRRTRPMVAAFGAGIIRRCLDESLAYAQQRRTMGQPIIRHQAIGHKLADMQIRLEAARQLTYLAAWLAD
QGEDNTMAAAVAKAFAADSAMWAATEAVQVFGGNGYSPDYPVEKLFRDAKLLQIYEGTSEIQRNIIVRELVRRSRGKDRR
PGEEPLE

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=390, Percent_Identity=42.5641025641026, Blast_Score=311, Evalue=1e-84,
Organism=Homo sapiens, GI187960098, Length=390, Percent_Identity=42.5641025641026, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=37.7005347593583, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI4557233, Length=379, Percent_Identity=39.0501319261214, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=37.7659574468085, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=39.6969696969697, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI21361497, Length=349, Percent_Identity=34.9570200573066, Blast_Score=214, Evalue=8e-56,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=34.4, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI4557235, Length=380, Percent_Identity=33.6842105263158, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI76496475, Length=380, Percent_Identity=33.6842105263158, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=29.5212765957447, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI48976061, Length=421, Percent_Identity=30.6413301662708, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI211971008, Length=421, Percent_Identity=30.6413301662708, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=29.5212765957447, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=29.3628808864266, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI38505218, Length=403, Percent_Identity=29.5285359801489, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI87081958, Length=389, Percent_Identity=30.5912596401028, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1786223, Length=390, Percent_Identity=29.7435897435897, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87082384, Length=276, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081702, Length=332, Percent_Identity=26.2048192771084, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=42.6701570680628, Blast_Score=316, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=42.2680412371134, Blast_Score=310, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI17534899, Length=389, Percent_Identity=41.6452442159383, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=37.027027027027, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=37.2031662269129, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17506239, Length=380, Percent_Identity=35.5263157894737, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=31.0344827586207, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71985184, Length=380, Percent_Identity=29.4736842105263, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=36.231884057971, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=32.8413284132841, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=28.9893617021277, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=30.0531914893617, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=37.719298245614, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=327, Percent_Identity=29.3577981651376, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=28.3068783068783, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=31.3807531380753, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=336, Percent_Identity=26.7857142857143, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI86563381, Length=285, Percent_Identity=27.719298245614, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=285, Percent_Identity=27.719298245614, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17531913, Length=185, Percent_Identity=29.1891891891892, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24660351, Length=388, Percent_Identity=45.1030927835052, Blast_Score=321, Evalue=5e-88,
Organism=Drosophila melanogaster, GI21356377, Length=387, Percent_Identity=37.4677002583979, Blast_Score=247, Evalue=9e-66,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=38.3202099737533, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=35.4838709677419, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=35.0923482849604, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI281363737, Length=404, Percent_Identity=32.9207920792079, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=27.6762402088773, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44839; Mature: 44708

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEYTGGGAMLASREASVDFSLTAEQRELQERARRFAETVVKPVATYYDQEERHPHELIV
CCCCCCCCCEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RARAEGLTEITIPREYGGRGLGVLELVLVAEQLAWACAGFTAAACSSCLAGEPIVIAGSE
HHHHCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEECCC
EQKRRWLPRLAAGEYASFALTEPDAGSDVAALATRAERCGDVYVLNGHKRWIGNAPIASF
HHHHHHCCHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCEECCCCCHHHE
FVVFAKTDPQAGHNGISVFVVERESTGIVTRPLRKLGQRAISNGEIEFHDVVVPANQRIG
EEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCHHCC
REGEGFAIAMQTLRRTRPMVAAFGAGIIRRCLDESLAYAQQRRTMGQPIIRHQAIGHKLA
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
DMQIRLEAARQLTYLAAWLADQGEDNTMAAAVAKAFAADSAMWAATEAVQVFGGNGYSPD
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCC
YPVEKLFRDAKLLQIYEGTSEIQRNIIVRELVRRSRGKDRRPGEEPLE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PEYTGGGAMLASREASVDFSLTAEQRELQERARRFAETVVKPVATYYDQEERHPHELIV
CCCCCCCCEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RARAEGLTEITIPREYGGRGLGVLELVLVAEQLAWACAGFTAAACSSCLAGEPIVIAGSE
HHHHCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEECCC
EQKRRWLPRLAAGEYASFALTEPDAGSDVAALATRAERCGDVYVLNGHKRWIGNAPIASF
HHHHHHCCHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEECCCCEECCCCCHHHE
FVVFAKTDPQAGHNGISVFVVERESTGIVTRPLRKLGQRAISNGEIEFHDVVVPANQRIG
EEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCHHCC
REGEGFAIAMQTLRRTRPMVAAFGAGIIRRCLDESLAYAQQRRTMGQPIIRHQAIGHKLA
CCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
DMQIRLEAARQLTYLAAWLADQGEDNTMAAAVAKAFAADSAMWAATEAVQVFGGNGYSPD
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCC
YPVEKLFRDAKLLQIYEGTSEIQRNIIVRELVRRSRGKDRRPGEEPLE
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]