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The map label for this gene is sppA [H]

Identifier: 221633251

GI number: 221633251

Start: 1256623

End: 1257588

Strand: Reverse

Name: sppA [H]

Synonym: trd_1269

Alternate gene names: 221633251

Gene position: 1257588-1256623 (Counterclockwise)

Preceding gene: 221633252

Following gene: 221633247

Centisome position: 62.79

GC content: 66.05

Gene sequence:

>966_bases
ATGCCTGCAGCGAGGACAACTCGTCGCACCTGGTGGATCGTCGGGCTCAGTCTCCTGCTGGTTGCGAGCTGCCTCGCGCT
GACGGCCGGGCTCGGCATGCTCGCATCGGGCAGACTCGACCGCTGGCTGGAGCAGCCGCATGTCGCTGAGATCCGTGTCC
GCGGGCCCATCGCGCTCCGCGGTGGGGCCGGTCTGTTGACCGGCGAGTCGGCGAGCGCCGAGCGGATCGTCGAGCAACTG
GAGCGAGCGCGCCAAAACCCGAATGCCAGAGTCGTCCTGTTGCGCGTCGATAGTCCGGGGGGTGGCGTCAATGCGGCGCG
CGAGATCTGGGCAGCAGTGCGACGTGTGCAGGAATCCGGGAAGCCAGTCGTGGCCTTTTTCGAGGACACTGCCGCGTCCG
GCGGTTATTACATCAGTGCGCCGGCCGACCGTATCGTCGCCATGCCTGACACCATCACCGGCAGTATCGGGGTGATCCTG
ATCATTCCTGACCTGTCCGGCTTGTACGAGAAACTGGGCATTCGCATGCAAGTCGTCAAGAGCGGCACCTTCAAGGACAT
GGCGTCGAGCGATCGTCCGTTGACTCCAGAAGAGCGCGCACTGCTCGAGCAGCTGGTTCACGAGGCCTACGACGAGTTCG
TGCGAGTCGTCGCCGAGGGTCGCGCGATGCCACCCGAGCGCGTGCGCGAGTTGGCTGACGGCCGCATCTACACTGGGCGC
CAGGCGAAAGAGCTCGGGCTCGTCGATGAACTCGGCGGCTACCGTGACGCCCTGGCAGTAGCTGGCCAGCTGGCTGGACT
GGGAGCGGAACCAGCGGTCCGCGTCTATCGCCCGCAGCCGACCTTTTGGGAATCGTTGAGCAGGACCACGGCGCGATTCT
TGTTCGGCCGGGACGATGCGGGGCCGGTGGGAGTCCTCCCGACCGGCCCGATCGAGCTACGCTACGAGCTCGCTACGCTC
GGTTGA

Upstream 100 bases:

>100_bases
GGAAGTGGTCTCGATCATCCAGCGGCAACGCCTGCGCGGACTCACTGGCCAGGCTGATAACGATTGACTCGTGGTCGGAG
TGTCGGAAGGAAATGGTGGG

Downstream 100 bases:

>100_bases
TCTCAGTCATCGGAACCAGGCTGGATGGCGGACGGGACCTGAGCGAGCCGGTTCTCGAGAAACGGCGTGAGGAGATCGAT
CGGCACCGGGAAAATGATGG

Product: protease IV, signal peptide peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MPAARTTRRTWWIVGLSLLLVASCLALTAGLGMLASGRLDRWLEQPHVAEIRVRGPIALRGGAGLLTGESASAERIVEQL
ERARQNPNARVVLLRVDSPGGGVNAAREIWAAVRRVQESGKPVVAFFEDTAASGGYYISAPADRIVAMPDTITGSIGVIL
IIPDLSGLYEKLGIRMQVVKSGTFKDMASSDRPLTPEERALLEQLVHEAYDEFVRVVAEGRAMPPERVRELADGRIYTGR
QAKELGLVDELGGYRDALAVAGQLAGLGAEPAVRVYRPQPTFWESLSRTTARFLFGRDDAGPVGVLPTGPIELRYELATL
G

Sequences:

>Translated_321_residues
MPAARTTRRTWWIVGLSLLLVASCLALTAGLGMLASGRLDRWLEQPHVAEIRVRGPIALRGGAGLLTGESASAERIVEQL
ERARQNPNARVVLLRVDSPGGGVNAAREIWAAVRRVQESGKPVVAFFEDTAASGGYYISAPADRIVAMPDTITGSIGVIL
IIPDLSGLYEKLGIRMQVVKSGTFKDMASSDRPLTPEERALLEQLVHEAYDEFVRVVAEGRAMPPERVRELADGRIYTGR
QAKELGLVDELGGYRDALAVAGQLAGLGAEPAVRVYRPQPTFWESLSRTTARFLFGRDDAGPVGVLPTGPIELRYELATL
G
>Mature_320_residues
PAARTTRRTWWIVGLSLLLVASCLALTAGLGMLASGRLDRWLEQPHVAEIRVRGPIALRGGAGLLTGESASAERIVEQLE
RARQNPNARVVLLRVDSPGGGVNAAREIWAAVRRVQESGKPVVAFFEDTAASGGYYISAPADRIVAMPDTITGSIGVILI
IPDLSGLYEKLGIRMQVVKSGTFKDMASSDRPLTPEERALLEQLVHEAYDEFVRVVAEGRAMPPERVRELADGRIYTGRQ
AKELGLVDELGGYRDALAVAGQLAGLGAEPAVRVYRPQPTFWESLSRTTARFLFGRDDAGPVGVLPTGPIELRYELATLG

Specific function: Digestion of the cleaved signal peptides [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=208, Percent_Identity=37.5, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787527, Length=161, Percent_Identity=31.055900621118, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 34678; Mature: 34547

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAARTTRRTWWIVGLSLLLVASCLALTAGLGMLASGRLDRWLEQPHVAEIRVRGPIALR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEECCEEEE
GGAGLLTGESASAERIVEQLERARQNPNARVVLLRVDSPGGGVNAAREIWAAVRRVQESG
CCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
KPVVAFFEDTAASGGYYISAPADRIVAMPDTITGSIGVILIIPDLSGLYEKLGIRMQVVK
CCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCEEEEEECCCHHHHHHHCCEEEEEC
SGTFKDMASSDRPLTPEERALLEQLVHEAYDEFVRVVAEGRAMPPERVRELADGRIYTGR
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEECCC
QAKELGLVDELGGYRDALAVAGQLAGLGAEPAVRVYRPQPTFWESLSRTTARFLFGRDDA
CHHHCCCHHHHCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCC
GPVGVLPTGPIELRYELATLG
CCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
PAARTTRRTWWIVGLSLLLVASCLALTAGLGMLASGRLDRWLEQPHVAEIRVRGPIALR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEECCEEEE
GGAGLLTGESASAERIVEQLERARQNPNARVVLLRVDSPGGGVNAAREIWAAVRRVQESG
CCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
KPVVAFFEDTAASGGYYISAPADRIVAMPDTITGSIGVILIIPDLSGLYEKLGIRMQVVK
CCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCEEEEEECCCHHHHHHHCCEEEEEC
SGTFKDMASSDRPLTPEERALLEQLVHEAYDEFVRVVAEGRAMPPERVRELADGRIYTGR
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEECCC
QAKELGLVDELGGYRDALAVAGQLAGLGAEPAVRVYRPQPTFWESLSRTTARFLFGRDDA
CHHHCCCHHHHCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCC
GPVGVLPTGPIELRYELATLG
CCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]