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The map label for this gene is prsA [H]

Identifier: 221633228

GI number: 221633228

Start: 1231652

End: 1233046

Strand: Reverse

Name: prsA [H]

Synonym: trd_1246

Alternate gene names: 221633228

Gene position: 1233046-1231652 (Counterclockwise)

Preceding gene: 221633229

Following gene: 221633227

Centisome position: 61.56

GC content: 64.52

Gene sequence:

>1395_bases
ATGCTCGAGTGGGTGAGGCGGCTCTTTCCCCGCCGATGGGGGGATCGCAGGGCGCGAACACATCGGCGGGTTCCTCGTCG
CGAGCGGGAACGAGTACAGGAGCGAGCAGCAGTCATCGGTGTATCGGTTGTTCTGCTGCTCGTGGCTGGGTTACTCGGCG
GTGGAGCGATCTACCAGTATTGGTACCTGCCGCGCCAGGTCGTCGTCGAAGTCAACGGTGAGCCGATCACCCGCGCCGAC
TACTGGAAGATGCGGCGCCTGGAACTCTTGAATCAGATCAGTCAATACCAACAGTTGGCCAATCTCATGAGTGGTCAGCA
GAGTGTCCAGTACCAACAGCTCGCTGACCAGGCTCGCCAGCAGCTGACGACCGTCGAGCGTGATCCGATCAATCAGGCAA
CGGTCGGGCAAATGATTGATGACCGTCTGGTGCTTCAGCGTATGGGACAACTCGGCGTTGCGCTCGACGAGCGAGAGGTG
GAGGACTATACCGTCAGCCTGTTCAGCAGTGTTCCCCTGCTCACGCCGACACCGACGCTCGGGATCGATCCGACCGCTGC
GGCCTGGGCTACCGCGACAGCGGCGGTGACGCCGACCCCACTTCCGACACCAACTCCGGAGCCCGGGGTTACCCCGACGC
CGCAGGCAACCCCGACGCCAACGCCGAGTGAATCGCCGACACCGACGCCGACGGTCCCACCCGAGGAGGCGCGGGCGACA
GCGACAGCGCTCATGGGGGAGTATCAGAAGAACGTGCTCGAACAGGCCGGTCTCTCCCTGGCTGACTTCCAGCGATTGGT
CGTGCGGCCGATGCTGGCTCGGGAGAAAGTGCAGCGTGTCCTGGAAGAGCGGATCCCCCTGCGAGCCGAGCAGATCCACG
CTGCACACATCTTGTTGGCGACTCGCGAGGCGGCAGAGCAGGCGCTGGCCGATATCCAGGGTGGAGCTGACTTCGCGACG
ATCGCTCGCGAGCGATCGATCGACAGCGATACCGCACCGAACGGCGGAGACCTGGGATGGTTGCCGCGCGGCTATATGCC
GAGTGCGTTCGACGAGGTGGCGTTCGCTCTCGCACCCGGAGAGGTCGGCGGCCCGGTGCAGACCCAGTATGGTTGGCACA
TCGTGAAGGTGCTGGAACGTGATCCTGATCGACCCCTGAGCGAGCGCATGTTGCAGGCGTTGCGGGGGCAAGCCTTGAGC
CGTTGGCTCGACGAGCAACGCCGAACCTCGACGATTCGCTGGCATCTCGGGTTGACTCCGCTGCCCACGCCAGCTGTCCA
GCCGTTCGTGGCCCCACCAGACGCGCCGCCGACTCCGACCCCGACTCCCACTCCAACGACCGTGCCAGGAACACCGACCG
TGGAGGTATCGCCGACCGCAACGCCACTGCCATAA

Upstream 100 bases:

>100_bases
CGGCATCTTGCCCTCCTGCCCTTCGTGCCGGAACGATAACGTTCGTCCGCTGATTCCTCCTCTGGGATCGCGTCGAGGCA
GGAACGCTGCGAGGTGCTAG

Downstream 100 bases:

>100_bases
TGGCTGAGCGAGCGTTGTCCGGCTGGCTGCTCGACGTGGGAGATCGAGGAGGCCCGCGGAATGCAGGGTCGAGGATCGGT
AAGGTACCGCGCGCGGGCTG

Product: putative post-translocation molecular chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MLEWVRRLFPRRWGDRRARTHRRVPRRERERVQERAAVIGVSVVLLLVAGLLGGGAIYQYWYLPRQVVVEVNGEPITRAD
YWKMRRLELLNQISQYQQLANLMSGQQSVQYQQLADQARQQLTTVERDPINQATVGQMIDDRLVLQRMGQLGVALDEREV
EDYTVSLFSSVPLLTPTPTLGIDPTAAAWATATAAVTPTPLPTPTPEPGVTPTPQATPTPTPSESPTPTPTVPPEEARAT
ATALMGEYQKNVLEQAGLSLADFQRLVVRPMLAREKVQRVLEERIPLRAEQIHAAHILLATREAAEQALADIQGGADFAT
IARERSIDSDTAPNGGDLGWLPRGYMPSAFDEVAFALAPGEVGGPVQTQYGWHIVKVLERDPDRPLSERMLQALRGQALS
RWLDEQRRTSTIRWHLGLTPLPTPAVQPFVAPPDAPPTPTPTPTPTTVPGTPTVEVSPTATPLP

Sequences:

>Translated_464_residues
MLEWVRRLFPRRWGDRRARTHRRVPRRERERVQERAAVIGVSVVLLLVAGLLGGGAIYQYWYLPRQVVVEVNGEPITRAD
YWKMRRLELLNQISQYQQLANLMSGQQSVQYQQLADQARQQLTTVERDPINQATVGQMIDDRLVLQRMGQLGVALDEREV
EDYTVSLFSSVPLLTPTPTLGIDPTAAAWATATAAVTPTPLPTPTPEPGVTPTPQATPTPTPSESPTPTPTVPPEEARAT
ATALMGEYQKNVLEQAGLSLADFQRLVVRPMLAREKVQRVLEERIPLRAEQIHAAHILLATREAAEQALADIQGGADFAT
IARERSIDSDTAPNGGDLGWLPRGYMPSAFDEVAFALAPGEVGGPVQTQYGWHIVKVLERDPDRPLSERMLQALRGQALS
RWLDEQRRTSTIRWHLGLTPLPTPAVQPFVAPPDAPPTPTPTPTPTTVPGTPTVEVSPTATPLP
>Mature_464_residues
MLEWVRRLFPRRWGDRRARTHRRVPRRERERVQERAAVIGVSVVLLLVAGLLGGGAIYQYWYLPRQVVVEVNGEPITRAD
YWKMRRLELLNQISQYQQLANLMSGQQSVQYQQLADQARQQLTTVERDPINQATVGQMIDDRLVLQRMGQLGVALDEREV
EDYTVSLFSSVPLLTPTPTLGIDPTAAAWATATAAVTPTPLPTPTPEPGVTPTPQATPTPTPSESPTPTPTVPPEEARAT
ATALMGEYQKNVLEQAGLSLADFQRLVVRPMLAREKVQRVLEERIPLRAEQIHAAHILLATREAAEQALADIQGGADFAT
IARERSIDSDTAPNGGDLGWLPRGYMPSAFDEVAFALAPGEVGGPVQTQYGWHIVKVLERDPDRPLSERMLQALRGQALS
RWLDEQRRTSTIRWHLGLTPLPTPAVQPFVAPPDAPPTPTPTPTPTTVPGTPTVEVSPTATPLP

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=93, Percent_Identity=41.9354838709677, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786238, Length=156, Percent_Identity=32.0512820512821, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 51171; Mature: 51171

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEWVRRLFPRRWGDRRARTHRRVPRRERERVQERAAVIGVSVVLLLVAGLLGGGAIYQY
CHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
WYLPRQVVVEVNGEPITRADYWKMRRLELLNQISQYQQLANLMSGQQSVQYQQLADQARQ
HHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QLTTVERDPINQATVGQMIDDRLVLQRMGQLGVALDEREVEDYTVSLFSSVPLLTPTPTL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
GIDPTAAAWATATAAVTPTPLPTPTPEPGVTPTPQATPTPTPSESPTPTPTVPPEEARAT
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
ATALMGEYQKNVLEQAGLSLADFQRLVVRPMLAREKVQRVLEERIPLRAEQIHAAHILLA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TREAAEQALADIQGGADFATIARERSIDSDTAPNGGDLGWLPRGYMPSAFDEVAFALAPG
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
EVGGPVQTQYGWHIVKVLERDPDRPLSERMLQALRGQALSRWLDEQRRTSTIRWHLGLTP
CCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
LPTPAVQPFVAPPDAPPTPTPTPTPTTVPGTPTVEVSPTATPLP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MLEWVRRLFPRRWGDRRARTHRRVPRRERERVQERAAVIGVSVVLLLVAGLLGGGAIYQY
CHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
WYLPRQVVVEVNGEPITRADYWKMRRLELLNQISQYQQLANLMSGQQSVQYQQLADQARQ
HHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QLTTVERDPINQATVGQMIDDRLVLQRMGQLGVALDEREVEDYTVSLFSSVPLLTPTPTL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
GIDPTAAAWATATAAVTPTPLPTPTPEPGVTPTPQATPTPTPSESPTPTPTVPPEEARAT
CCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
ATALMGEYQKNVLEQAGLSLADFQRLVVRPMLAREKVQRVLEERIPLRAEQIHAAHILLA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TREAAEQALADIQGGADFATIARERSIDSDTAPNGGDLGWLPRGYMPSAFDEVAFALAPG
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
EVGGPVQTQYGWHIVKVLERDPDRPLSERMLQALRGQALSRWLDEQRRTSTIRWHLGLTP
CCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
LPTPAVQPFVAPPDAPPTPTPTPTPTTVPGTPTVEVSPTATPLP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA