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The map label for this gene is nagD [H]

Identifier: 221633054

GI number: 221633054

Start: 1044698

End: 1045582

Strand: Reverse

Name: nagD [H]

Synonym: trd_1070

Alternate gene names: 221633054

Gene position: 1045582-1044698 (Counterclockwise)

Preceding gene: 221633056

Following gene: 221633053

Centisome position: 52.2

GC content: 61.47

Gene sequence:

>885_bases
ATGCTCGGCGAGAGAAAGCACGGCGTCAAGATGCGAGTGGGAGCGAGGATCGAGCGAATCATGGAGAGCGGAACAGCTGT
GGTCGAAGCGGTACTCGCCGAGGTCTGCGGTATCGCCTTCGATATGGACGGCGTGTTGTACCGTGGCGAGCATGTCTTGC
CGGGAGCAGTGGAGCTCGTCACTGAGCTCCAGCGTCGTGGAATCCCTTTTGCCATGGTGACGAATAACTCGACGCGGACG
CCCGAGGAGTACGCGGCGAAGCTCGCTCGTCTCGGCATGACAGTTGCCGCTGAGCAGATCGTGACATCGGGAATCGCGAC
GCGCGACTGGATGCGTCTGCACTACCGACCTGGCACGCGCGTCTATGTCTTGGGTATGCCGGCATTGGTAGAAGCGATCC
TCGGCGACGGGCGCTTCGTCTCGGCTGGGCGTGATGCCGAAGTCGTGGTGAGCGGAGCAGATTTCACCCTGACCTACGAG
AAACTCAAGATCGCCACGTTGGCGATCCGCGATGGTGCTGACTGGATCGCGACGAACGCGGATCGCACTTTTCCTTCAGA
GGACGGACTGATTCCTGGCTCTGGTGCTATCGTTGCGGCGCTGCAGGCAGCGACGGATCGGACACCGCTCGTGATCGGTA
AGCCCGAGCCGGCCATGCTGTTGCGTGCTGCCGACGTGATGGGTCTGTCACCGCACGAACTCCTCGTCATCGGTGACCGA
TTGGATACCGATGTCCTGGCAGGCAAGCGAGCCGGTGCGCGAACCGCTCTCGTCCTCACGGGAGTGAGTACGCGGGAAGA
TCTCACCATGACCGAATGGCTTCCCGATCTGGTTTTGAGCGATTTGCGTGAGCTGCTCGCGGCGGTACGGAGCCTTCGAT
GGTGA

Upstream 100 bases:

>100_bases
CTCAATACGATCTCGGCGACCTTTGGGTCGAAAGGCGCTTCGTTCATGCTTCGCTCGTCTCCCGGCTCGAACTTCCACAA
GACACGATCGACACTATGCT

Downstream 100 bases:

>100_bases
AAGAGGTCGGCCGGTACCGGGTCGATGATCCCCGGACGATTCAAGGCCGGGACGACGTTTCGCCGTGCGGGTGGCATCTC
GGCGCCCTGCGGTTGCGGTT

Product: N-acetylglucosamine-6-phoshatase or p-nitrophenyl phosphatase

Products: 4-nitrophenol; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLGERKHGVKMRVGARIERIMESGTAVVEAVLAEVCGIAFDMDGVLYRGEHVLPGAVELVTELQRRGIPFAMVTNNSTRT
PEEYAAKLARLGMTVAAEQIVTSGIATRDWMRLHYRPGTRVYVLGMPALVEAILGDGRFVSAGRDAEVVVSGADFTLTYE
KLKIATLAIRDGADWIATNADRTFPSEDGLIPGSGAIVAALQAATDRTPLVIGKPEPAMLLRAADVMGLSPHELLVIGDR
LDTDVLAGKRAGARTALVLTGVSTREDLTMTEWLPDLVLSDLRELLAAVRSLRW

Sequences:

>Translated_294_residues
MLGERKHGVKMRVGARIERIMESGTAVVEAVLAEVCGIAFDMDGVLYRGEHVLPGAVELVTELQRRGIPFAMVTNNSTRT
PEEYAAKLARLGMTVAAEQIVTSGIATRDWMRLHYRPGTRVYVLGMPALVEAILGDGRFVSAGRDAEVVVSGADFTLTYE
KLKIATLAIRDGADWIATNADRTFPSEDGLIPGSGAIVAALQAATDRTPLVIGKPEPAMLLRAADVMGLSPHELLVIGDR
LDTDVLAGKRAGARTALVLTGVSTREDLTMTEWLPDLVLSDLRELLAAVRSLRW
>Mature_294_residues
MLGERKHGVKMRVGARIERIMESGTAVVEAVLAEVCGIAFDMDGVLYRGEHVLPGAVELVTELQRRGIPFAMVTNNSTRT
PEEYAAKLARLGMTVAAEQIVTSGIATRDWMRLHYRPGTRVYVLGMPALVEAILGDGRFVSAGRDAEVVVSGADFTLTYE
KLKIATLAIRDGADWIATNADRTFPSEDGLIPGSGAIVAALQAATDRTPLVIGKPEPAMLLRAADVMGLSPHELLVIGDR
LDTDVLAGKRAGARTALVLTGVSTREDLTMTEWLPDLVLSDLRELLAAVRSLRW

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI108796653, Length=299, Percent_Identity=34.1137123745819, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI10092677, Length=269, Percent_Identity=37.1747211895911, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI14149777, Length=222, Percent_Identity=30.1801801801802, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI269847098, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786890, Length=245, Percent_Identity=31.0204081632653, Blast_Score=130, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17562458, Length=289, Percent_Identity=30.1038062283737, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17558880, Length=298, Percent_Identity=29.5302013422819, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560956, Length=282, Percent_Identity=30.4964539007092, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193210059, Length=269, Percent_Identity=31.9702602230483, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI86563050, Length=268, Percent_Identity=30.9701492537313, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71984613, Length=279, Percent_Identity=27.9569892473118, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319965, Length=251, Percent_Identity=31.0756972111554, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24666141, Length=301, Percent_Identity=28.2392026578073, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24656330, Length=285, Percent_Identity=29.4736842105263, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641437, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920940, Length=248, Percent_Identity=27.4193548387097, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.41

Molecular weight: Translated: 31686; Mature: 31686

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGERKHGVKMRVGARIERIMESGTAVVEAVLAEVCGIAFDMDGVLYRGEHVLPGAVELV
CCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCEEECCCCCCCHHHHHH
TELQRRGIPFAMVTNNSTRTPEEYAAKLARLGMTVAAEQIVTSGIATRDWMRLHYRPGTR
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
VYVLGMPALVEAILGDGRFVSAGRDAEVVVSGADFTLTYEKLKIATLAIRDGADWIATNA
EEEEECHHHHHHHHCCCEEEECCCCCEEEEECCCEEEEHHHEEEEEEEEECCCCEEECCC
DRTFPSEDGLIPGSGAIVAALQAATDRTPLVIGKPEPAMLLRAADVMGLSPHELLVIGDR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHEEHHHHCCCCCCEEEEECCC
LDTDVLAGKRAGARTALVLTGVSTREDLTMTEWLPDLVLSDLRELLAAVRSLRW
CCCHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLGERKHGVKMRVGARIERIMESGTAVVEAVLAEVCGIAFDMDGVLYRGEHVLPGAVELV
CCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCEEECCCCCCCHHHHHH
TELQRRGIPFAMVTNNSTRTPEEYAAKLARLGMTVAAEQIVTSGIATRDWMRLHYRPGTR
HHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
VYVLGMPALVEAILGDGRFVSAGRDAEVVVSGADFTLTYEKLKIATLAIRDGADWIATNA
EEEEECHHHHHHHHCCCEEEECCCCCEEEEECCCEEEEHHHEEEEEEEEECCCCEEECCC
DRTFPSEDGLIPGSGAIVAALQAATDRTPLVIGKPEPAMLLRAADVMGLSPHELLVIGDR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHEEHHHHCCCCCCEEEEECCC
LDTDVLAGKRAGARTALVLTGVSTREDLTMTEWLPDLVLSDLRELLAAVRSLRW
CCCHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-nitrophenyl phosphate; H2O

Specific reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA