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The map label for this gene is ttuD [H]

Identifier: 221633016

GI number: 221633016

Start: 996327

End: 997637

Strand: Reverse

Name: ttuD [H]

Synonym: trd_1031

Alternate gene names: 221633016

Gene position: 997637-996327 (Counterclockwise)

Preceding gene: 221633017

Following gene: 221633014

Centisome position: 49.81

GC content: 63.69

Gene sequence:

>1311_bases
ATGCCCGGTCCGAGATTGAAAGCGTTTGCCGAGAAGGTTTTTCAACAGGCGCTGAGCGCAGTCGATCCCGAACGCTCGGT
TCGCGAGGCGCTGCAATTGACTGAACGGTTCCTCGTCGTACGGGGCGTTCCGCATCGGTTGGAGCCGACGAGTCAACTAG
TGGTCATTGCGGTCGGCAAGGCGGCTGCCTCGATGGCCCGTGGAGCGCTGGCGGTGTTAGGGGGGCGAGTCACACGCTGC
GTGGTCGTCCCGAAAGCCGATGGCTGGAGCGACCGTGCGTTCGCGGGGTGTCGAGTCATACCGGGTGCGCACCCGGTGCC
CGATGCACGCAGTCTGGAAGCTGGGCAGGCCTTGCTCGATGCGGTTCGCGGACTGCATTCCACTGATCTCGTCCTCGTGC
TTCTTTCTGGTGGTGGCTCTGCCTTGGCCGAAGTGCCGCGCGATTGTTTGACACTCGATGACCTCGTGCTGACCACAGAC
GAGCTGCTGCGGGCAGGAGCCGATATCTGGTTACTGAATGCGGTGCGGCGACGTCTCAGTGCGATCAAAGGGGGAGGTCT
GGCGCGGGCCGCCGCACCAGCCCGAGTCGTCAATTTGATCGTTTCGGATGTTTTGGGAAATCCGCTCCCGGTTATCGCGA
GCGGACCGACCGTGGAACCAACGACCATTTTCGAGGATGTCGTCGGCGCTGTGCAGCGGCTCGGTGTCTGGGCCCGACTA
CCGGAGCGGGTGCGAGCGATTTTGAGCGAACCCGAGTCAGAACGGGTTGTGCTCGCGAACGTCCTGCAGACGGTCATTCT
GGCCGATGTCACGGTTCTCGTACGAGCTGCTGCCGAGGCTTGTCAGGCCTGGGGGTTACCCTCCGTCATCTGCGGCACGC
GCTATACAGGTGAAGCTCGGGAGTTCGGTCGTTTTTGGGCGGCACTTGCCCGCTCGGTGCGTAGCGATCGGCAACCTTGG
GCACCTCCGGTCGCACTGGTAGCCGGGGGTGAGCTCACTGTGACGGTTCGCGGAGGTGGGCGAGGGGGGCGGAACACCGA
GATGGCGCTGGCCGCAGCAATGTCGCTCGAGGATGCTCCTGGAATCACGATCGCGAGCTTTGCTTCCGACGGGGATGACG
GCACGAGTGGAGCTGCGGGAGCGGTGGTCGACGCGACGACTGTGGCAGCGTTGCGAGCGCAGGGTATCGACGCGGGACGC
GCGCTGAGTGAAAACGACTCGGCGACGGTGCTGGACCGGGTCGATGCCCTCGTACGTACCGGTCTGACTGGCACGAACGT
GAACGATCTCTACCTCGCGATTGTCGAGTGA

Upstream 100 bases:

>100_bases
ATCCGACGACCGGTCAAGCGATCGAGCTCGAGACACCGCTTCCGTACGATCTGCGGACTGTTCTCGAGGCGCTGCGTCAT
TGCGAGCAGGAGCAGGCGCG

Downstream 100 bases:

>100_bases
GCGTTTTGGTCACCGTGTGAGCATGGTGGTATCGATGGGTGGACGCGGCAGCCATCCCATCCGTTGGAGGGCTTCGCGCC
CGAGGAGACCCAGCGTTATG

Product: putative hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MPGPRLKAFAEKVFQQALSAVDPERSVREALQLTERFLVVRGVPHRLEPTSQLVVIAVGKAAASMARGALAVLGGRVTRC
VVVPKADGWSDRAFAGCRVIPGAHPVPDARSLEAGQALLDAVRGLHSTDLVLVLLSGGGSALAEVPRDCLTLDDLVLTTD
ELLRAGADIWLLNAVRRRLSAIKGGGLARAAAPARVVNLIVSDVLGNPLPVIASGPTVEPTTIFEDVVGAVQRLGVWARL
PERVRAILSEPESERVVLANVLQTVILADVTVLVRAAAEACQAWGLPSVICGTRYTGEAREFGRFWAALARSVRSDRQPW
APPVALVAGGELTVTVRGGGRGGRNTEMALAAAMSLEDAPGITIASFASDGDDGTSGAAGAVVDATTVAALRAQGIDAGR
ALSENDSATVLDRVDALVRTGLTGTNVNDLYLAIVE

Sequences:

>Translated_436_residues
MPGPRLKAFAEKVFQQALSAVDPERSVREALQLTERFLVVRGVPHRLEPTSQLVVIAVGKAAASMARGALAVLGGRVTRC
VVVPKADGWSDRAFAGCRVIPGAHPVPDARSLEAGQALLDAVRGLHSTDLVLVLLSGGGSALAEVPRDCLTLDDLVLTTD
ELLRAGADIWLLNAVRRRLSAIKGGGLARAAAPARVVNLIVSDVLGNPLPVIASGPTVEPTTIFEDVVGAVQRLGVWARL
PERVRAILSEPESERVVLANVLQTVILADVTVLVRAAAEACQAWGLPSVICGTRYTGEAREFGRFWAALARSVRSDRQPW
APPVALVAGGELTVTVRGGGRGGRNTEMALAAAMSLEDAPGITIASFASDGDDGTSGAAGAVVDATTVAALRAQGIDAGR
ALSENDSATVLDRVDALVRTGLTGTNVNDLYLAIVE
>Mature_435_residues
PGPRLKAFAEKVFQQALSAVDPERSVREALQLTERFLVVRGVPHRLEPTSQLVVIAVGKAAASMARGALAVLGGRVTRCV
VVPKADGWSDRAFAGCRVIPGAHPVPDARSLEAGQALLDAVRGLHSTDLVLVLLSGGGSALAEVPRDCLTLDDLVLTTDE
LLRAGADIWLLNAVRRRLSAIKGGGLARAAAPARVVNLIVSDVLGNPLPVIASGPTVEPTTIFEDVVGAVQRLGVWARLP
ERVRAILSEPESERVVLANVLQTVILADVTVLVRAAAEACQAWGLPSVICGTRYTGEAREFGRFWAALARSVRSDRQPWA
PPVALVAGGELTVTVRGGGRGGRNTEMALAAAMSLEDAPGITIASFASDGDDGTSGAAGAVVDATTVAALRAQGIDAGRA
LSENDSATVLDRVDALVRTGLTGTNVNDLYLAIVE

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=486, Percent_Identity=34.156378600823, Blast_Score=199, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI193205461, Length=448, Percent_Identity=30.5803571428571, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI19920578, Length=484, Percent_Identity=28.9256198347107, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 45341; Mature: 45209

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPRLKAFAEKVFQQALSAVDPERSVREALQLTERFLVVRGVPHRLEPTSQLVVIAVGK
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECH
AAASMARGALAVLGGRVTRCVVVPKADGWSDRAFAGCRVIPGAHPVPDARSLEAGQALLD
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHH
AVRGLHSTDLVLVLLSGGGSALAEVPRDCLTLDDLVLTTDELLRAGADIWLLNAVRRRLS
HHHCCCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AIKGGGLARAAAPARVVNLIVSDVLGNPLPVIASGPTVEPTTIFEDVVGAVQRLGVWARL
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
PERVRAILSEPESERVVLANVLQTVILADVTVLVRAAAEACQAWGLPSVICGTRYTGEAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHH
EFGRFWAALARSVRSDRQPWAPPVALVAGGELTVTVRGGGRGGRNTEMALAAAMSLEDAP
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEEECCCCCCCCHHHHHHHHHCCCCCC
GITIASFASDGDDGTSGAAGAVVDATTVAALRAQGIDAGRALSENDSATVLDRVDALVRT
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHC
GLTGTNVNDLYLAIVE
CCCCCCCCCEEEEEEC
>Mature Secondary Structure 
PGPRLKAFAEKVFQQALSAVDPERSVREALQLTERFLVVRGVPHRLEPTSQLVVIAVGK
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECH
AAASMARGALAVLGGRVTRCVVVPKADGWSDRAFAGCRVIPGAHPVPDARSLEAGQALLD
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHH
AVRGLHSTDLVLVLLSGGGSALAEVPRDCLTLDDLVLTTDELLRAGADIWLLNAVRRRLS
HHHCCCCCCEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AIKGGGLARAAAPARVVNLIVSDVLGNPLPVIASGPTVEPTTIFEDVVGAVQRLGVWARL
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
PERVRAILSEPESERVVLANVLQTVILADVTVLVRAAAEACQAWGLPSVICGTRYTGEAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHH
EFGRFWAALARSVRSDRQPWAPPVALVAGGELTVTVRGGGRGGRNTEMALAAAMSLEDAP
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEEECCCCCCCCHHHHHHHHHCCCCCC
GITIASFASDGDDGTSGAAGAVVDATTVAALRAQGIDAGRALSENDSATVLDRVDALVRT
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHC
GLTGTNVNDLYLAIVE
CCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]