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The map label for this gene is rpe [H]

Identifier: 221632631

GI number: 221632631

Start: 604730

End: 605437

Strand: Reverse

Name: rpe [H]

Synonym: trd_0613

Alternate gene names: 221632631

Gene position: 605437-604730 (Counterclockwise)

Preceding gene: 221632637

Following gene: 221632629

Centisome position: 30.23

GC content: 62.29

Gene sequence:

>708_bases
ATGACGACCACCTTCGGTTATCGGCTTCCGATGCTCTCGCCGTCGATCTTGAACGCCGATTTCGGTCACCTGGCCGCCGT
CGTCCGCGAGCTGGATGAGGCTGGCGCTGACGCCATCCACCTCGACATCATGGACGGCCGGTTCGTCCCGAACATCAGCT
TCGGCCTCCCGATCGTCCGTGCCGTCCGTGATGCGACGACCTTACCCTTGGATGTCCACTTGATGATCGTCGAACCGGAG
CGTTACCTCGAAGCGTTCGCCCAGGCCGGTGCCAGCGCTTTGACCGTCCATGTCGAAACCTGCCCACACCTCCACCGGAC
CATTCAAGCCATTCACGAACTCGGGCTTCTCGCCGGAGTAGCGCTCAATCCCGCGACCCCGCTCGCTGCGATCGAGGAGA
TTCTGCCCTTCGTCGATCTCGTACTGATCATGACAGTCGATCCGGGCTTTGGTGGGCAAGGCCTCATTCCCGCGGTACTC
GGGAAACTTCGGCGCTTGCGCCAGATGGTCGATGAACGAGGGTTCCGCTGCCTGCTCTCGGTCGACGGCGGCGTCAAACT
CTCCAACCTGGAATCGGTCATCTCGGCTGGTGCCGATATCGTCGTGACCGGTTCCGTCCTCTTCACGGCCGAGGAACGGC
CCGGCGAAATTCTCCGTCGTCTGCGTGAACGCGCGACGCAAGCCTATCGGACGCGATCCCTCCGGTAA

Upstream 100 bases:

>100_bases
CGCACTTCCTCCTCTGCTTCTCTGCAAGCATAGCCGAAGGCGGAATGAGTACACTGACCCGCACAGTGCTCGGTTCGGTC
GAGCGCGAGAGGACACGCAG

Downstream 100 bases:

>100_bases
GCGTTCCGAATCACGGTATGGCCAGGCTGCAACGATCCGGTCTCTTTCCTCTGCTCTCGGGCCGCGGCGACCCGCGCGAA
CTCACCGGTGCCCGACCCAG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTTTFGYRLPMLSPSILNADFGHLAAVVRELDEAGADAIHLDIMDGRFVPNISFGLPIVRAVRDATTLPLDVHLMIVEPE
RYLEAFAQAGASALTVHVETCPHLHRTIQAIHELGLLAGVALNPATPLAAIEEILPFVDLVLIMTVDPGFGGQGLIPAVL
GKLRRLRQMVDERGFRCLLSVDGGVKLSNLESVISAGADIVVTGSVLFTAEERPGEILRRLRERATQAYRTRSLR

Sequences:

>Translated_235_residues
MTTTFGYRLPMLSPSILNADFGHLAAVVRELDEAGADAIHLDIMDGRFVPNISFGLPIVRAVRDATTLPLDVHLMIVEPE
RYLEAFAQAGASALTVHVETCPHLHRTIQAIHELGLLAGVALNPATPLAAIEEILPFVDLVLIMTVDPGFGGQGLIPAVL
GKLRRLRQMVDERGFRCLLSVDGGVKLSNLESVISAGADIVVTGSVLFTAEERPGEILRRLRERATQAYRTRSLR
>Mature_234_residues
TTTFGYRLPMLSPSILNADFGHLAAVVRELDEAGADAIHLDIMDGRFVPNISFGLPIVRAVRDATTLPLDVHLMIVEPER
YLEAFAQAGASALTVHVETCPHLHRTIQAIHELGLLAGVALNPATPLAAIEEILPFVDLVLIMTVDPGFGGQGLIPAVLG
KLRRLRQMVDERGFRCLLSVDGGVKLSNLESVISAGADIVVTGSVLFTAEERPGEILRRLRERATQAYRTRSLR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=229, Percent_Identity=36.6812227074236, Blast_Score=151, Evalue=4e-37,
Organism=Homo sapiens, GI219879828, Length=229, Percent_Identity=35.3711790393013, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI24307923, Length=185, Percent_Identity=30.2702702702703, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1789788, Length=199, Percent_Identity=45.2261306532663, Blast_Score=187, Evalue=4e-49,
Organism=Escherichia coli, GI1790523, Length=210, Percent_Identity=37.1428571428571, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1790754, Length=202, Percent_Identity=33.1683168316832, Blast_Score=110, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17552948, Length=209, Percent_Identity=38.2775119617225, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322341, Length=238, Percent_Identity=33.1932773109244, Blast_Score=156, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24586301, Length=213, Percent_Identity=37.5586854460094, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25504; Mature: 25373

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTFGYRLPMLSPSILNADFGHLAAVVRELDEAGADAIHLDIMDGRFVPNISFGLPIVR
CCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHH
AVRDATTLPLDVHLMIVEPERYLEAFAQAGASALTVHVETCPHLHRTIQAIHELGLLAGV
HHHHCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHC
ALNPATPLAAIEEILPFVDLVLIMTVDPGFGGQGLIPAVLGKLRRLRQMVDERGFRCLLS
CCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
VDGGVKLSNLESVISAGADIVVTGSVLFTAEERPGEILRRLRERATQAYRTRSLR
ECCCEEHHHHHHHHHCCCCEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTTFGYRLPMLSPSILNADFGHLAAVVRELDEAGADAIHLDIMDGRFVPNISFGLPIVR
CCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHH
AVRDATTLPLDVHLMIVEPERYLEAFAQAGASALTVHVETCPHLHRTIQAIHELGLLAGV
HHHHCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHC
ALNPATPLAAIEEILPFVDLVLIMTVDPGFGGQGLIPAVLGKLRRLRQMVDERGFRCLLS
CCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
VDGGVKLSNLESVISAGADIVVTGSVLFTAEERPGEILRRLRERATQAYRTRSLR
ECCCEEHHHHHHHHHCCCCEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]