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The map label for this gene is hypE [C]

Identifier: 221632628

GI number: 221632628

Start: 600118

End: 601149

Strand: Reverse

Name: hypE [C]

Synonym: trd_0606

Alternate gene names: 221632628

Gene position: 601149-600118 (Counterclockwise)

Preceding gene: 221632629

Following gene: 221632626

Centisome position: 30.01

GC content: 64.05

Gene sequence:

>1032_bases
GTGAGCGACAGGCCTCTACCGACCGGGAAGCTTCCTCCCCAACTCCTGGCTGAATTTCTCGGGAATCTTTCTCCGGATCC
GAGCGTCCTGCTCGGTCCTGGTATCGGTCACGATGCCGCGGTCATCCAAATCGATACTATCCGGCTGGTGTTCAAGAGCG
ACCCGATCACTTTCGCGACCGAGGCGATCGGCTGGTATGCCCTCAACGTCAATGCCAACGATGTCGCCTGCCTCGGTGCT
CGCCCGCGCTGGTTTCTCGCGACTGTCCTCCTCCCCGAGGGAACGACAGCTCACGACGCGCAAGTCATCCTCGATGACCT
CGCTCGGGCCGCCGAGCGACTCGGCGTCAGCGTGGTCGGTGGTCATACGGAAATCACGGTCGGGCTCGATCGTCCCATCG
TCGCCGGCACCATGATCGGAGAACTCACGACCGAGTACGTTCTGTCACCGGCCCGCGTGCGGCCGGGAGATGCGCTTCTC
TTAGTGCGCGGCATTGCCATCGAAGGGACTGCTCTCCTCGCACGCGAGTGCCGCCAGACGCTCGAGCGGATGCTCGACCA
AGATCTGCTCGCTCGCTGCCGTCGCTTTTTGTACGAGCCGGGCATCAGCATCGTCCCCGCCGCTACCCTCCTGCTCGAGA
GACTGGGTGAGGACCTCCGTTACTTGCATGATCCCACGGAAGGTGGGCTCGCCACCGGCCTCCACGAGGTTGCTGTTGCC
TGCGGTACTGGCCTCGTCGTCTCGGAGGAGGCGATCCTCGTCTATCCGGAAACCCGCGCCGTGTGCACTGCGCTGGGTTT
GGATCCGCTCGGTCTCATCGCTTCTGGAGCGCTCCTCGCTGTCGTCACGCCGGAAAGCGTCGAGCACGCGCTCGACACTT
TAGCGCAGCACGATATCCCCGCAACGCAACTCGGCTGGCTCGACCCTGATCCCGGTCGTCGTGTCCTCATCGGGTCGACT
GGCGAACGACCGCTCCCCGTCTTTCAGGTCGACGAGGTCGCGCGCCTCTTCGCGAGCGGTGGCTGTGTCTAG

Upstream 100 bases:

>100_bases
GTCGCACGCGGCCCACGGCTGGTCCCTCTCGATCATCCCCTCGTTCGCGCAGCGCGTGGAATCGGAATCAGTTTCGCGCA
ACAGGACGAGGAGTGAACGC

Downstream 100 bases:

>100_bases
GGTTGCTTGGGCATCGCGCTGAGCGCTCGATACGCCGGACGCGGAGACCAGTCAGGGTTGAGCACTGACCATGGTCCTTT
CTCATCTTCTGGCCCGACGA

Product: hydrogenase expression/formation

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSDRPLPTGKLPPQLLAEFLGNLSPDPSVLLGPGIGHDAAVIQIDTIRLVFKSDPITFATEAIGWYALNVNANDVACLGA
RPRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVGGHTEITVGLDRPIVAGTMIGELTTEYVLSPARVRPGDALL
LVRGIAIEGTALLARECRQTLERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGEDLRYLHDPTEGGLATGLHEVAVA
CGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHDIPATQLGWLDPDPGRRVLIGST
GERPLPVFQVDEVARLFASGGCV

Sequences:

>Translated_343_residues
MSDRPLPTGKLPPQLLAEFLGNLSPDPSVLLGPGIGHDAAVIQIDTIRLVFKSDPITFATEAIGWYALNVNANDVACLGA
RPRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVGGHTEITVGLDRPIVAGTMIGELTTEYVLSPARVRPGDALL
LVRGIAIEGTALLARECRQTLERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGEDLRYLHDPTEGGLATGLHEVAVA
CGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHDIPATQLGWLDPDPGRRVLIGST
GERPLPVFQVDEVARLFASGGCV
>Mature_342_residues
SDRPLPTGKLPPQLLAEFLGNLSPDPSVLLGPGIGHDAAVIQIDTIRLVFKSDPITFATEAIGWYALNVNANDVACLGAR
PRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVGGHTEITVGLDRPIVAGTMIGELTTEYVLSPARVRPGDALLL
VRGIAIEGTALLARECRQTLERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGEDLRYLHDPTEGGLATGLHEVAVAC
GTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHDIPATQLGWLDPDPGRRVLIGSTG
ERPLPVFQVDEVARLFASGGCV

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=259, Percent_Identity=29.3436293436293, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36377; Mature: 36246

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRPLPTGKLPPQLLAEFLGNLSPDPSVLLGPGIGHDAAVIQIDTIRLVFKSDPITFAT
CCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEEEEEEEEECCCCEEEE
EAIGWYALNVNANDVACLGARPRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVG
CCCEEEEEEECCCCEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEC
GHTEITVGLDRPIVAGTMIGELTTEYVLSPARVRPGDALLLVRGIAIEGTALLARECRQT
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHH
LERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGEDLRYLHDPTEGGLATGLHEVAVA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
CGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHDIP
HCCCEEEECCEEEEECCHHHHHHHCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCC
ATQLGWLDPDPGRRVLIGSTGERPLPVFQVDEVARLFASGGCV
CHHCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDRPLPTGKLPPQLLAEFLGNLSPDPSVLLGPGIGHDAAVIQIDTIRLVFKSDPITFAT
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEEEEEEEEECCCCEEEE
EAIGWYALNVNANDVACLGARPRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVG
CCCEEEEEEECCCCEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEC
GHTEITVGLDRPIVAGTMIGELTTEYVLSPARVRPGDALLLVRGIAIEGTALLARECRQT
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHH
LERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGEDLRYLHDPTEGGLATGLHEVAVA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
CGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHDIP
HCCCEEEECCEEEEECCHHHHHHHCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCC
ATQLGWLDPDPGRRVLIGSTGERPLPVFQVDEVARLFASGGCV
CHHCCCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]