| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is fabG [C]
Identifier: 221632328
GI number: 221632328
Start: 302041
End: 302862
Strand: Reverse
Name: fabG [C]
Synonym: trd_0298
Alternate gene names: 221632328
Gene position: 302862-302041 (Counterclockwise)
Preceding gene: 221632329
Following gene: 221632327
Centisome position: 15.12
GC content: 62.41
Gene sequence:
>822_bases ATGCAACGACAGCAGCGTTTCGATCTGAACGGCATGGTCGCACTGGTGACCGGCGCTGGCGGTGGCTCGCGCGGTGGACT CGGCCCGCTCATCGCCCGGGCACTCGCCGAGTCGGGTTCGAGGATCGCGATCAACGATCGGACTCCCGAACGGGCACGAG AGACAGTCGCTGAGCTGCGAGCTGCCGGCTACGATGCAGTCGAGGCATTTCCGGCCGATGTGGCCAACTCGGCTCAGGTC GATCGCTTGATCGCACAGGTCGTCGAGCGTTTCGGCCAACTGGATATTCTGGTCAACAAGGCAGAGGCACATGGCAGCGG TCGCCGCTCGGACCAGGTATCCGATGACGAATGGGAGTCCCTCCTCGCAGTGAACACGCATGCTCCCTTCTATCTCAGTC GAGCGGCAGTGCGGCATATGCGACAGCGCAGGTTCGGTCGCATCATTCATGTGTCGCACATCACAGCCAGCCGCACCAGT GCGCTGAACGGCGTCGCTTATGTTGCAGCCAAAGAAGCGCTGTACGGATTGATACGCCACCTGTCGATCGAAGTCGCGCA ACATGGGATCACGGTCAACGCGATCCTCCCCGGCTTCATCGTGACCCCGAAGCTGCTCCACGGATGGGAGGAGGAACGCG TACAACGCCTCGCGGAGACCATACCGATTCGACGAGCCGGGACACCGGAGGAAGTGGCCGCACTCGTCGTGTTCCTGGCG AGCCATGAAGCGAGCTACATCACCGGTGCGGCGATTCCGATCGATGGTGCGGTTTCCGTCGTACCAGGTGGCCGTACCGA TCCAGCGTCTGCCTTCGCGTGA
Upstream 100 bases:
>100_bases CAAGCGAACAGCATCGACGAGCACGACCAGCACGATGGTCTCGATGCCCTCCTAGCCAATCAGTGGTCTCTGCACGCCGA CGATGGAGCAGGAGGAACGG
Downstream 100 bases:
>100_bases AGAGAGGAGCAGGTGCGATGGGACGACTCACAGGACTCGTCGCCCTCGTGACCGGAGCTGGGGGCGGAGAAATGGGAGGT GGCGGCGCAGGGATCGCACG
Product: putative 3-oxoacyl-(acyl carrier protein) reductase
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 273; Mature: 273
Protein sequence:
>273_residues MQRQQRFDLNGMVALVTGAGGGSRGGLGPLIARALAESGSRIAINDRTPERARETVAELRAAGYDAVEAFPADVANSAQV DRLIAQVVERFGQLDILVNKAEAHGSGRRSDQVSDDEWESLLAVNTHAPFYLSRAAVRHMRQRRFGRIIHVSHITASRTS ALNGVAYVAAKEALYGLIRHLSIEVAQHGITVNAILPGFIVTPKLLHGWEEERVQRLAETIPIRRAGTPEEVAALVVFLA SHEASYITGAAIPIDGAVSVVPGGRTDPASAFA
Sequences:
>Translated_273_residues MQRQQRFDLNGMVALVTGAGGGSRGGLGPLIARALAESGSRIAINDRTPERARETVAELRAAGYDAVEAFPADVANSAQV DRLIAQVVERFGQLDILVNKAEAHGSGRRSDQVSDDEWESLLAVNTHAPFYLSRAAVRHMRQRRFGRIIHVSHITASRTS ALNGVAYVAAKEALYGLIRHLSIEVAQHGITVNAILPGFIVTPKLLHGWEEERVQRLAETIPIRRAGTPEEVAALVVFLA SHEASYITGAAIPIDGAVSVVPGGRTDPASAFA >Mature_273_residues MQRQQRFDLNGMVALVTGAGGGSRGGLGPLIARALAESGSRIAINDRTPERARETVAELRAAGYDAVEAFPADVANSAQV DRLIAQVVERFGQLDILVNKAEAHGSGRRSDQVSDDEWESLLAVNTHAPFYLSRAAVRHMRQRRFGRIIHVSHITASRTS ALNGVAYVAAKEALYGLIRHLSIEVAQHGITVNAILPGFIVTPKLLHGWEEERVQRLAETIPIRRAGTPEEVAALVVFLA SHEASYITGAAIPIDGAVSVVPGGRTDPASAFA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=35.0393700787402, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=29.3893129770992, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=31.3207547169811, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=33.739837398374, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=31.9148936170213, Blast_Score=104, Evalue=8e-23, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=29.9610894941634, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=33.195020746888, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI66933014, Length=232, Percent_Identity=28.448275862069, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4504505, Length=261, Percent_Identity=32.183908045977, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=33.6842105263158, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=28, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI4503817, Length=224, Percent_Identity=30.3571428571429, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=32.8205128205128, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=203, Percent_Identity=30.0492610837438, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=27.9166666666667, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI31542939, Length=217, Percent_Identity=29.9539170506912, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4758504, Length=266, Percent_Identity=29.3233082706767, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=26.8, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI4503301, Length=240, Percent_Identity=23.75, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=28.1407035175879, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI210032110, Length=204, Percent_Identity=27.9411764705882, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=34.4827586206897, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=33.852140077821, Blast_Score=127, Evalue=6e-31, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=36.0153256704981, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=35.2226720647773, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=34.3629343629344, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=33.6032388663968, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=32.5581395348837, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=27.734375, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=34.0336134453782, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1786812, Length=268, Percent_Identity=29.8507462686567, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=29.8804780876494, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789378, Length=238, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=35.9683794466403, Blast_Score=129, Evalue=1e-30, Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=30.8823529411765, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=31.3207547169811, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17560150, Length=257, Percent_Identity=31.1284046692607, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=31.2741312741313, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.5660377358491, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=31.1284046692607, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=30.3703703703704, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=31.3953488372093, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562908, Length=273, Percent_Identity=31.5018315018315, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560220, Length=276, Percent_Identity=30.7971014492754, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=30.0751879699248, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=31.9852941176471, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=30.2919708029197, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=29.6875, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=30.3370786516854, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17563726, Length=252, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=29.3233082706767, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=31.0204081632653, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17565030, Length=278, Percent_Identity=30.5755395683453, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=29.296875, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=26.7716535433071, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=29.368029739777, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17568967, Length=206, Percent_Identity=31.0679611650485, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=28.8537549407115, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=29.6153846153846, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=28.1853281853282, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17564282, Length=264, Percent_Identity=26.8939393939394, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=26.171875, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI193203115, Length=252, Percent_Identity=26.5873015873016, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203117, Length=257, Percent_Identity=25.2918287937743, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=30.6513409961686, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI71997099, Length=211, Percent_Identity=30.8056872037915, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71982365, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=28.8537549407115, Blast_Score=85, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=27.7992277992278, Blast_Score=81, Evalue=2e-16, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=32.5396825396825, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=33.203125, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=33.4630350194552, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=30.2325581395349, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=32.1428571428571, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=29.2, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24644337, Length=234, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI18859837, Length=201, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=28.2442748091603, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=27.1653543307087, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24584744, Length=199, Percent_Identity=30.6532663316583, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI28574402, Length=199, Percent_Identity=30.6532663316583, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=27.8048780487805, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 29249; Mature: 29249
Theoretical pI: Translated: 8.03; Mature: 8.03
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQRQQRFDLNGMVALVTGAGGGSRGGLGPLIARALAESGSRIAINDRTPERARETVAELR CCCCHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH AAGYDAVEAFPADVANSAQVDRLIAQVVERFGQLDILVNKAEAHGSGRRSDQVSDDEWES HCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHCCEEEEEECHHCCCCCCCCCCCCCHHHHH LLAVNTHAPFYLSRAAVRHMRQRRFGRIIHVSHITASRTSALNGVAYVAAKEALYGLIRH EEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH LSIEVAQHGITVNAILPGFIVTPKLLHGWEEERVQRLAETIPIRRAGTPEEVAALVVFLA HHHHHHHCCEEEEEECCCHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH SHEASYITGAAIPIDGAVSVVPGGRTDPASAFA HCCCCCEECCCCCCCCCEEECCCCCCCCCCCCC >Mature Secondary Structure MQRQQRFDLNGMVALVTGAGGGSRGGLGPLIARALAESGSRIAINDRTPERARETVAELR CCCCHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH AAGYDAVEAFPADVANSAQVDRLIAQVVERFGQLDILVNKAEAHGSGRRSDQVSDDEWES HCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHCCEEEEEECHHCCCCCCCCCCCCCHHHHH LLAVNTHAPFYLSRAAVRHMRQRRFGRIIHVSHITASRTSALNGVAYVAAKEALYGLIRH EEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH LSIEVAQHGITVNAILPGFIVTPKLLHGWEEERVQRLAETIPIRRAGTPEEVAALVVFLA HHHHHHHCCEEEEEECCCHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH SHEASYITGAAIPIDGAVSVVPGGRTDPASAFA HCCCCCEECCCCCCCCCEEECCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]