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The map label for this gene is lplA [H]

Identifier: 221632176

GI number: 221632176

Start: 153163

End: 154236

Strand: Reverse

Name: lplA [H]

Synonym: trd_0142

Alternate gene names: 221632176

Gene position: 154236-153163 (Counterclockwise)

Preceding gene: 221632177

Following gene: 221632175

Centisome position: 7.7

GC content: 63.5

Gene sequence:

>1074_bases
GTGCGTGTCCGCGTCGTCGATCTCGGTCTGGTCGACCCAATCCGCTCCCAGAGTGTCTACCACGCCGTCGGGTACACCTT
CCGATCCGACACGCTACCGACCATCCTGCTCGTCTCACCGACCACCCCCTATGTGTCGATCGGCTTCCATCAGGATGCTG
AGCGCGAGGTGGATCTCGACTACTGCCGGAGCGTGGGCCTCCCGGTCATCCGCCGCGAGGTGGGTGGGGGGGCTGTGTAT
CTGGATCAGCACCAGGTTTTCACCCAGTGGATCTTTCCGCGCGCGCTGGTGCCGCTTCGCCTGGAGGAGCGTTTCGCCTG
GTACGTCCGCCCCTTCGTCGAAACCTACCGTCGTTGGGGAATCGAAGCGACGTGGCGACCGATCAACGATGTCCACGTAC
GGGGGCGGAAGATCGGCGGAACGGGTGCCGCGAGCATCGGGGAAGCTGAGATTCTCGTCGGCAGCCTGATGCTCGATTTC
GACACACGGCAGATGGCGCGCGTGCTCAAGGTCGCCTCGGAGAAGATGCGCGATAAGGTGTTCGAGAGTCTCGAGGAGTA
CATGACCACCATGCATCGCGAACTCGGAACGCTCCCAGATCGCGACGCTGTCGTAGAGACCTATCTGGAATGCTGTGCGG
CGGCACTCGGGGCAGAAATCGAGTTCGGCACGCTGACCCCGGAAGAAGAAGCGATGGCCGCTGAACTCGACGAGCGGTTC
GCTTCCGAAGAGTGGTTGTACCAAAAGGGTGGGCTCCGCCAATCGGGAATCAAGATCCATGCCGATGTGCACTTGCACGA
GGCAGCACTCAAGGTACCTGGCGGCCTCATCCGCGTGATCGTGCGGACGCACCGGGGCCGCATCGACGATATCAGCATCA
GCGGTGACTTCACGCTCCTACCGGCACTGGGGTTGGCAGCCATCGAACAGGCTGTCCGCGGTCTCGCCCTGCGCCGCGAG
GAGCTCACGGCCCGAGTTCGGGACGTCTATCGCGCACTCGGCTTGCAATCGCCAGGCGTCAGCCCGGACGACTTCGCCGC
CGCGATCCTGCGTGCCGTGGAAAGCATGCGCTGA

Upstream 100 bases:

>100_bases
CTCGTCACCGGCGAGGAGGCGTTCACCCGCTATCGTGCGCGGATCGATGCGTTGGATCTCAACTGCTTCCGCTGTGCCGA
GTGACTGAAAGGAGGAAACG

Downstream 100 bases:

>100_bases
GCACGATAGCACCCTCGCCCTGGTCGGCTATCGATGAGCGACCCGCAGGCCCTTCTCGTCGCCATGCCGGCAGATCCTCG
CATTCTGTCGACTGAACACT

Product: hypothetical protein

Products: NA

Alternate protein names: Lipoate--protein ligase subunit 1 [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRVRVVDLGLVDPIRSQSVYHAVGYTFRSDTLPTILLVSPTTPYVSIGFHQDAEREVDLDYCRSVGLPVIRREVGGGAVY
LDQHQVFTQWIFPRALVPLRLEERFAWYVRPFVETYRRWGIEATWRPINDVHVRGRKIGGTGAASIGEAEILVGSLMLDF
DTRQMARVLKVASEKMRDKVFESLEEYMTTMHRELGTLPDRDAVVETYLECCAAALGAEIEFGTLTPEEEAMAAELDERF
ASEEWLYQKGGLRQSGIKIHADVHLHEAALKVPGGLIRVIVRTHRGRIDDISISGDFTLLPALGLAAIEQAVRGLALRRE
ELTARVRDVYRALGLQSPGVSPDDFAAAILRAVESMR

Sequences:

>Translated_357_residues
MRVRVVDLGLVDPIRSQSVYHAVGYTFRSDTLPTILLVSPTTPYVSIGFHQDAEREVDLDYCRSVGLPVIRREVGGGAVY
LDQHQVFTQWIFPRALVPLRLEERFAWYVRPFVETYRRWGIEATWRPINDVHVRGRKIGGTGAASIGEAEILVGSLMLDF
DTRQMARVLKVASEKMRDKVFESLEEYMTTMHRELGTLPDRDAVVETYLECCAAALGAEIEFGTLTPEEEAMAAELDERF
ASEEWLYQKGGLRQSGIKIHADVHLHEAALKVPGGLIRVIVRTHRGRIDDISISGDFTLLPALGLAAIEQAVRGLALRRE
ELTARVRDVYRALGLQSPGVSPDDFAAAILRAVESMR
>Mature_357_residues
MRVRVVDLGLVDPIRSQSVYHAVGYTFRSDTLPTILLVSPTTPYVSIGFHQDAEREVDLDYCRSVGLPVIRREVGGGAVY
LDQHQVFTQWIFPRALVPLRLEERFAWYVRPFVETYRRWGIEATWRPINDVHVRGRKIGGTGAASIGEAEILVGSLMLDF
DTRQMARVLKVASEKMRDKVFESLEEYMTTMHRELGTLPDRDAVVETYLECCAAALGAEIEFGTLTPEEEAMAAELDERF
ASEEWLYQKGGLRQSGIKIHADVHLHEAALKVPGGLIRVIVRTHRGRIDDISISGDFTLLPALGLAAIEQAVRGLALRRE
ELTARVRDVYRALGLQSPGVSPDDFAAAILRAVESMR

Specific function: Lipoate-protein ligase catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. This subunit can alone only catalyze the lipoat

COG id: COG0095

COG function: function code H; Lipoate-protein ligase A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lplA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.7.7.63 [H]

Molecular weight: Translated: 40002; Mature: 40002

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRVVDLGLVDPIRSQSVYHAVGYTFRSDTLPTILLVSPTTPYVSIGFHQDAEREVDLD
CEEEEEECCCCCCHHCCHHHHHHCCEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCHH
YCRSVGLPVIRREVGGGAVYLDQHQVFTQWIFPRALVPLRLEERFAWYVRPFVETYRRWG
HHHHCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
IEATWRPINDVHVRGRKIGGTGAASIGEAEILVGSLMLDFDTRQMARVLKVASEKMRDKV
CCEECCCCCHHEECCEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FESLEEYMTTMHRELGTLPDRDAVVETYLECCAAALGAEIEFGTLTPEEEAMAAELDERF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHH
ASEEWLYQKGGLRQSGIKIHADVHLHEAALKVPGGLIRVIVRTHRGRIDDISISGDFTLL
CHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHH
PALGLAAIEQAVRGLALRREELTARVRDVYRALGLQSPGVSPDDFAAAILRAVESMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVRVVDLGLVDPIRSQSVYHAVGYTFRSDTLPTILLVSPTTPYVSIGFHQDAEREVDLD
CEEEEEECCCCCCHHCCHHHHHHCCEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCHH
YCRSVGLPVIRREVGGGAVYLDQHQVFTQWIFPRALVPLRLEERFAWYVRPFVETYRRWG
HHHHCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
IEATWRPINDVHVRGRKIGGTGAASIGEAEILVGSLMLDFDTRQMARVLKVASEKMRDKV
CCEECCCCCHHEECCEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FESLEEYMTTMHRELGTLPDRDAVVETYLECCAAALGAEIEFGTLTPEEEAMAAELDERF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHH
ASEEWLYQKGGLRQSGIKIHADVHLHEAALKVPGGLIRVIVRTHRGRIDDISISGDFTLL
CHHHHHHHCCCCCCCCEEEEEEEEEHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCHHH
PALGLAAIEQAVRGLALRREELTARVRDVYRALGLQSPGVSPDDFAAAILRAVESMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]