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The map label for this gene is tlpB [H]

Identifier: 221632135

GI number: 221632135

Start: 107247

End: 109193

Strand: Reverse

Name: tlpB [H]

Synonym: trd_0100

Alternate gene names: 221632135

Gene position: 109193-107247 (Counterclockwise)

Preceding gene: 221632136

Following gene: 221632134

Centisome position: 5.45

GC content: 63.23

Gene sequence:

>1947_bases
TTGGCGATCGAGAACGGCGCGGACGAGGAAACGGTGCAGCGCCTCCTGGCCGATAGCCAGAGAACGCGCCAGGACTATGA
AGAGCGGCTCTCCTATTGGAGAAGCGTACTGCCAGAAGGTGAGATCCGCCAGTCCTTGACCGAACAAGCAGCGGATCCTG
CCCGCGAGTTCTTCGACATCCGCGATCGCCAGGTGATTCCCGCTCTCCTCGCCGGGGAGACAGCTCGTGCGGAGGAACTC
ATCTGGAACGAGCTTCGACCCCGTTTCGAGGCGCACCGCAGCGCAATCGACCGCACAGTCGAACTCGGGTACGCCTCGGT
CAACAACTCGGAGCAGTCTGCCGAGGGTGTCGTCGCTCGAGTCAACGTTCTCGTTCCCGCTGTCAGTCTCATCAGCGCAC
TTTTGGCCACCCTCTTGGCCGCGCTCATGGCCCGCCTCTTGACCAAGCGCCTCGGACATGTGGCCAAGGCTCTCGACGAA
CTCACGACCCATGACATACCCGCCCTCGAGCGAGCGCTGGGTGCGCTCGCCCGCGGTGACCTGCGAGCGACCGTCTCGTT
CAAAGTGCGGCCGAGCGAGCTGACTGGGCGAGACGAAGTAGCGACACTGATCGGAGCCTACAATCGTCTCCAGTCCGCTC
TGGGTAATGTGGAACAGAGTTTTCGCACACTGGTCGAGGGCCTCCGCGACATGGTCACCAGCCTCAGAGGCGCGGCTGCT
CTGATCAACGATGTCGGGGCTGACGTCCATCGGCGTGTCGAACAGACGACCGTCGCCATCCAGAGTATGACCGGCGCGGC
TGAAAGAGTCGCCCGCGGAAGTGCCGATCAAGCCAATGCACTCACCGGATTGCGTCAGTCTTTGACCGAACTGGCTCAGA
CCAGTGACGCGCTCGCCAAGGCCGCTGCTGACCAAGCACGGGTCGTGCACCAGGCATTCGAGTTGGCTTCCGAGATCAAC
CGGCAGAATCGGGAGGCGGCGCAAACCGCCCGCGCGGTCGGTCGACTCGCAACAGAGCACGCCCAGCACGCACAGCGAGG
ACAGCGAGCGGTCGAGCGTACACTCGGCGCGATTACACGCGCTCAAGCCAAGAGCACCGAGGCGCAGAAGCGCGTGGACG
AGATGGTCAAGCATGCACAATCGATCGATCAGGTGCTCACGATCGTTCGCTCCATCACCGAACAAACGAACCTGCTCGCA
CTCAACGCCGCGATCGAGGCAGCGCGAGCCGGGGAAGCAGGACGAGGATTCGCCGTGGTCACTGAAGAAGTCCGGAAGCT
CTCCGCCAATGCTGCCGAAAGCACGACGCACATCGCCGAACTGGTCCACCAGTTGCAGAACTCGGCAGCGTCTGCCGGGC
AGGCAGCGACCGAAAGCCTCGAGGCGATGACCGGAGTCGTTACCGAAACCAACACGGTCTCGGATCTCTTCGAATCCACC
GCCGAGGCAGCCCGCGAACTCGCGACGTTGAGCGAGCGTGCACTCACCCTGGCCGAGCAAGCCCTGAAGAGTGTCGAATA
TCTGCGTGCACAACTCGAGCAAGCCGCATCGACAGTCGAGGAGACGAGCGCTGGGACTGCCGAACTCGCGACTTCCGTGG
CAACCATCAGTACCACCGCTTCCCAGCTTTCTGCGATCGGGGAAGAGAATGCCCAGGCAAGCGAGCACGCGAGCAACGCG
ATGGAAGAGATCAGCCACGAACTCTCAGAGGTGGCTCACAATGCGCAAGCCCTGTTCCAGCTCGCCCAGCAGCTGCTCCG
AGAGACGGAGCGCTTCCTCCTCGATCAGCCGGTTGCACACGCGCAAGCCGATTCCAGTCGGCGCCTGCTCCCAGTGGACT
CCGTCCACTCCCTGGGCGACGGGCTTGCCCTTCCAGTGGCAGCGAGTCGTACCGGGTCGCTGATGCCTGCCCCCAGCCGG
TGGACGAACGGTCATGGAGAGCCGTGA

Upstream 100 bases:

>100_bases
GTTGTATCAGCAGATCGCCCGCGATCAGGAATTGATCGCCGATATCTTGCCACCGCCGGCCTACATTGTCGATGCCTAAG
CCAATGTCCTCCAGCTCAAG

Downstream 100 bases:

>100_bases
TTGCGTCAGACGCCGTCACTCTCCATGTCCCTGGAGCCGCGCTCGGTCGAGGAGGTCGAGAAACTCACACCCGGACTCAG
GAGTGTTGCCCTTCTGCTGC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MAIENGADEETVQRLLADSQRTRQDYEERLSYWRSVLPEGEIRQSLTEQAADPAREFFDIRDRQVIPALLAGETARAEEL
IWNELRPRFEAHRSAIDRTVELGYASVNNSEQSAEGVVARVNVLVPAVSLISALLATLLAALMARLLTKRLGHVAKALDE
LTTHDIPALERALGALARGDLRATVSFKVRPSELTGRDEVATLIGAYNRLQSALGNVEQSFRTLVEGLRDMVTSLRGAAA
LINDVGADVHRRVEQTTVAIQSMTGAAERVARGSADQANALTGLRQSLTELAQTSDALAKAAADQARVVHQAFELASEIN
RQNREAAQTARAVGRLATEHAQHAQRGQRAVERTLGAITRAQAKSTEAQKRVDEMVKHAQSIDQVLTIVRSITEQTNLLA
LNAAIEAARAGEAGRGFAVVTEEVRKLSANAAESTTHIAELVHQLQNSAASAGQAATESLEAMTGVVTETNTVSDLFEST
AEAARELATLSERALTLAEQALKSVEYLRAQLEQAASTVEETSAGTAELATSVATISTTASQLSAIGEENAQASEHASNA
MEEISHELSEVAHNAQALFQLAQQLLRETERFLLDQPVAHAQADSSRRLLPVDSVHSLGDGLALPVAASRTGSLMPAPSR
WTNGHGEP

Sequences:

>Translated_648_residues
MAIENGADEETVQRLLADSQRTRQDYEERLSYWRSVLPEGEIRQSLTEQAADPAREFFDIRDRQVIPALLAGETARAEEL
IWNELRPRFEAHRSAIDRTVELGYASVNNSEQSAEGVVARVNVLVPAVSLISALLATLLAALMARLLTKRLGHVAKALDE
LTTHDIPALERALGALARGDLRATVSFKVRPSELTGRDEVATLIGAYNRLQSALGNVEQSFRTLVEGLRDMVTSLRGAAA
LINDVGADVHRRVEQTTVAIQSMTGAAERVARGSADQANALTGLRQSLTELAQTSDALAKAAADQARVVHQAFELASEIN
RQNREAAQTARAVGRLATEHAQHAQRGQRAVERTLGAITRAQAKSTEAQKRVDEMVKHAQSIDQVLTIVRSITEQTNLLA
LNAAIEAARAGEAGRGFAVVTEEVRKLSANAAESTTHIAELVHQLQNSAASAGQAATESLEAMTGVVTETNTVSDLFEST
AEAARELATLSERALTLAEQALKSVEYLRAQLEQAASTVEETSAGTAELATSVATISTTASQLSAIGEENAQASEHASNA
MEEISHELSEVAHNAQALFQLAQQLLRETERFLLDQPVAHAQADSSRRLLPVDSVHSLGDGLALPVAASRTGSLMPAPSR
WTNGHGEP
>Mature_647_residues
AIENGADEETVQRLLADSQRTRQDYEERLSYWRSVLPEGEIRQSLTEQAADPAREFFDIRDRQVIPALLAGETARAEELI
WNELRPRFEAHRSAIDRTVELGYASVNNSEQSAEGVVARVNVLVPAVSLISALLATLLAALMARLLTKRLGHVAKALDEL
TTHDIPALERALGALARGDLRATVSFKVRPSELTGRDEVATLIGAYNRLQSALGNVEQSFRTLVEGLRDMVTSLRGAAAL
INDVGADVHRRVEQTTVAIQSMTGAAERVARGSADQANALTGLRQSLTELAQTSDALAKAAADQARVVHQAFELASEINR
QNREAAQTARAVGRLATEHAQHAQRGQRAVERTLGAITRAQAKSTEAQKRVDEMVKHAQSIDQVLTIVRSITEQTNLLAL
NAAIEAARAGEAGRGFAVVTEEVRKLSANAAESTTHIAELVHQLQNSAASAGQAATESLEAMTGVVTETNTVSDLFESTA
EAARELATLSERALTLAEQALKSVEYLRAQLEQAASTVEETSAGTAELATSVATISTTASQLSAIGEENAQASEHASNAM
EEISHELSEVAHNAQALFQLAQQLLRETERFLLDQPVAHAQADSSRRLLPVDSVHSLGDGLALPVAASRTGSLMPAPSRW
TNGHGEP

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=220, Percent_Identity=32.7272727272727, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI2367378, Length=267, Percent_Identity=28.0898876404494, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787690, Length=474, Percent_Identity=25.1054852320675, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788195, Length=164, Percent_Identity=34.1463414634146, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789453, Length=130, Percent_Identity=36.1538461538462, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69538; Mature: 69407

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIENGADEETVQRLLADSQRTRQDYEERLSYWRSVLPEGEIRQSLTEQAADPAREFFDI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
RDRQVIPALLAGETARAEELIWNELRPRFEAHRSAIDRTVELGYASVNNSEQSAEGVVAR
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VNVLVPAVSLISALLATLLAALMARLLTKRLGHVAKALDELTTHDIPALERALGALARGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
LRATVSFKVRPSELTGRDEVATLIGAYNRLQSALGNVEQSFRTLVEGLRDMVTSLRGAAA
CEEEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINDVGADVHRRVEQTTVAIQSMTGAAERVARGSADQANALTGLRQSLTELAQTSDALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAADQARVVHQAFELASEINRQNREAAQTARAVGRLATEHAQHAQRGQRAVERTLGAITR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAKSTEAQKRVDEMVKHAQSIDQVLTIVRSITEQTNLLALNAAIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEEVRKLSANAAESTTHIAELVHQLQNSAASAGQAATESLEAMTGVVTETNTVSDLFEST
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AEAARELATLSERALTLAEQALKSVEYLRAQLEQAASTVEETSAGTAELATSVATISTTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SQLSAIGEENAQASEHASNAMEEISHELSEVAHNAQALFQLAQQLLRETERFLLDQPVAH
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AQADSSRRLLPVDSVHSLGDGLALPVAASRTGSLMPAPSRWTNGHGEP
HCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIENGADEETVQRLLADSQRTRQDYEERLSYWRSVLPEGEIRQSLTEQAADPAREFFDI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHH
RDRQVIPALLAGETARAEELIWNELRPRFEAHRSAIDRTVELGYASVNNSEQSAEGVVAR
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VNVLVPAVSLISALLATLLAALMARLLTKRLGHVAKALDELTTHDIPALERALGALARGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
LRATVSFKVRPSELTGRDEVATLIGAYNRLQSALGNVEQSFRTLVEGLRDMVTSLRGAAA
CEEEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LINDVGADVHRRVEQTTVAIQSMTGAAERVARGSADQANALTGLRQSLTELAQTSDALAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAADQARVVHQAFELASEINRQNREAAQTARAVGRLATEHAQHAQRGQRAVERTLGAITR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAKSTEAQKRVDEMVKHAQSIDQVLTIVRSITEQTNLLALNAAIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEEVRKLSANAAESTTHIAELVHQLQNSAASAGQAATESLEAMTGVVTETNTVSDLFEST
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AEAARELATLSERALTLAEQALKSVEYLRAQLEQAASTVEETSAGTAELATSVATISTTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SQLSAIGEENAQASEHASNAMEEISHELSEVAHNAQALFQLAQQLLRETERFLLDQPVAH
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AQADSSRRLLPVDSVHSLGDGLALPVAASRTGSLMPAPSRWTNGHGEP
HCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]