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The map label for this gene is murA1 [H]

Identifier: 221232691

GI number: 221232691

Start: 1930888

End: 1932171

Strand: Reverse

Name: murA1 [H]

Synonym: SPN23F_19860

Alternate gene names: 221232691

Gene position: 1932171-1930888 (Counterclockwise)

Preceding gene: 221232692

Following gene: 221232690

Centisome position: 86.98

GC content: 46.65

Gene sequence:

>1284_bases
ATGGATAAAATTGTGGTTCAAGGTGGCGATAATCGTCTGGTAGGAAGCGTGACGATCGAGGGAGCAAAAAATGCAGTCTT
ACCCTTGTTGGCAGCGACTATTCTAGCAAGTGAAGGAAAGACCGTCTTGCAGAATGTTCCGATTTTGTCGGATGTCTTTA
TTATGAATCAGGTAGTTGGTGGTTTGAATGCCAAGGTTGACTTTGATGAGGAAGCTCATCTTGTCAAGGTGGATGCTACT
GGCGACATCACTGAGGAAGCCCCTTACAAGTATGTCAGCAAGATGCGCGCCTCCATCGTTGTATTAGGGCCAATCCTTGC
CCGTGTGGGTCATACCAAGGTATCCATGCCAGGTGGTTGTACGATTGGTAGTCGTCCTATTGATCTTCATTTGAAAGGTC
TGGAAGCTATGGGGGTTAAGATTAGTCAGACAGCTGGTTACATCGAAGCCAAGGCAGAACGCTTGCATGGCGCTCATATC
TATATGGACTTTCCAAGTGTTGGTGCAACGCAGAACTTGATGATGGCAGCGACTCTGGCTGATGGGGTGACAGTGATTGA
GAATGCTGCGCGTGAGCCTGAGATTGTTGACTTAGCCATTCTCCTTAATGAAATGGGAGCCAAGGTCAAAGGTGCTGGTA
CAGAGACTATAACCATTACTGGTGTTGAGAAACTTCATGGTACGACTCACAATGTAGTCCAAGACCGTATCGAAGCAGGA
ACCTTTATGGTAGCTGCTGCCATGACTGGTGGTGATGTCTTGATTCGAGACGCTGTCTGGGAGCACAACCGTCCCTTGAT
TGCCAAGTTACTTGAAATGGGTGTTGAAGTAATTGAAGAAGACGAAGGAATTCGTGTTCGTTCTCAACTAGAAAATCTAA
AAGCTGTTCATGTGAAAACCTTGCCCCATCCAGGATTTCCAACAGATATGCAGGCTCAATTTACAGCCTTGATGACAGTT
GCAAAAGGCGAATCAACCATGGTGGAGACAGTTTTCGAAAATCGTTTCCAACACCTAGAAGAGATGCGCCGCATGGGCTT
GCATTCTGAGATTATCCGTGATACAGCTCGTATTGTTGGTGGACAGCCTTTGCAGGGAGCAGAAGTTCTTTCAACTGACC
TTCGTGCCAGTGCAGCCTTGATTTTGACAGGTTTGGTAGCACAGGGAGAAACTGTGGTCGGTAAATTGGTTCACTTGGAT
AGAGGTTACTACGGTTTCCATGAGAAGTTGGCGCAGCTAGGTGCTAAGATTCAGCGGATTGAGGCAAGTGATGAAGATGA
ATAA

Upstream 100 bases:

>100_bases
TCATAGGCTACATCCTGAGTTCTTTCTTTATTAGCCTGTATCATTTGTGGCAAGAAGCGCTTAGAGGATTATTATAAAAT
CAAGAGTAAAGGAAACGAGT

Downstream 100 bases:

>100_bases
GAAATCAAGCTACGTAGTCAAGCGTTTACTTTTAGTCATCATAGTACTGATTTTAGGTACTCTGGCTCTAGGAATCGGTT
TAATGGTAGGTTATGGAATC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDAT
GDITEEAPYKYVSKMRASIVVLGPILARVGHTKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAG
TFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTV
AKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLD
RGYYGFHEKLAQLGAKIQRIEASDEDE

Sequences:

>Translated_427_residues
MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDAT
GDITEEAPYKYVSKMRASIVVLGPILARVGHTKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAG
TFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTV
AKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLD
RGYYGFHEKLAQLGAKIQRIEASDEDE
>Mature_427_residues
MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDAT
GDITEEAPYKYVSKMRASIVVLGPILARVGHTKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAG
TFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTV
AKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLD
RGYYGFHEKLAQLGAKIQRIEASDEDE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=50.4739336492891, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45899; Mature: 45899

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVG
CCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHC
GLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHTKVSMPGGC
CCCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEEHHHHHHCCCCEECCCCCC
TIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLA
CCCCCCEEEEEECCHHHCEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCHHEEEHHHH
DGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAG
CCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEHHHHCCCHHHHHHHHHHCC
TFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKT
EEEEEEEECCCCEEEECHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEEEE
LPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVG
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHEEC
EASDEDE
CCCCCCC
>Mature Secondary Structure
MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVG
CCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHC
GLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHTKVSMPGGC
CCCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEEHHHHHHCCCCEECCCCCC
TIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLA
CCCCCCEEEEEECCHHHCEEEECCCCHHHHHHHHCCCEEEEEECCCCCCCCHHEEEHHHH
DGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAG
CCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEHHHHCCCHHHHHHHHHHCC
TFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKT
EEEEEEEECCCCEEEECHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEEEEE
LPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVG
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHEEC
EASDEDE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]