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The map label for this gene is aspC [H]

Identifier: 221232255

GI number: 221232255

Start: 1459846

End: 1461033

Strand: Reverse

Name: aspC [H]

Synonym: SPN23F_15070

Alternate gene names: 221232255

Gene position: 1461033-1459846 (Counterclockwise)

Preceding gene: 221232256

Following gene: 221232254

Centisome position: 65.77

GC content: 46.55

Gene sequence:

>1188_bases
ATGAAACTATCCAACCGTGTTTTAGAAATGGAAGAAAGTGTGACTTTGGCTGCTGGAGCCCGTGCCAAAGCACTGAAGGC
TGAGGGTAGAGATATTTTGTCTCTAACCTTGGGTGAGCCAGATTTCACTACTCCCAAAAATATCCAAGATGCCGCCATTG
CATCGATTCGAGATGGGCGTGCTTCTTTTTATACAGTAACCTCAGGTCTGCCAGAGCTTAAGGCGGCGGTCAATAGCTAC
TTTGAGCGCTTTTACGGCTATTCTGTAGCGTCAAATCAAGTGACAGTCGCTGCGGGAGCCAAATATTCTCTCTATACCTT
CTTTATGGCTGTGGTCAATCCAGGTGATGAAGTCATCATCCCAACCCCATACTGGGTTAGCTATGGAGATCAGGTCAAGA
TGGCAGAAGGCGTTCCCGTCTTTGTTTCTACTAAGGAAGACAATCACTTTAAGGTGACCGTAGATCAGTTAGAAGCAGCT
CGCACTGACAAGACCAAGGTTTTGGTGCTGAATTCGCCATCTAATCCCACAGGTATGATTTACACCCGTGAGGAACTCTT
GGCAATTGGAAACTGGGCTGTAGAAAATGATATTCTCATCCTAGCAGATGATATCTATGGCCGCTTGGTTTATAATGGTC
ATGAGTTCACACCGATTTCTAGCCTATCGGAAGCGATTCGCAAGCAAACAGTGGTCATCAATGGTGTGTCTAAAACCTAT
GCCATGACTGGTTGGCGGATTGGTTATGCCGTTGGAGAAGCAGATATTATCGCTGCCATGTCCAAGATTGCAGGTCAAAC
AACTTCGAATCCGTCAGCAGTAGCCCAATATGCAGCAGTTGAGGCTCTATCAGGTGAGCAAGATACTGTAGAAAGCATGC
GTCAGGCCTTTGAGGAACGTCTTAATACCATCTATCCCCTCCTTGCAGAGGTACCAGGATTTGAAGTGGTCAAACCGCAA
GGGGCCTTCTATCTCTTCCCAAATGTCAAAAAGGCCATGGAGATGAAAGGCTACACGGATGTGACAGACTTTACAACTGC
TATCTTAGAAGAAGCCGAAGTGGCCTTGGTAACAGGAGCTGGATTTGGAGCACCAGAAAATGTCCGCCTCAGCTATGCGA
CAGACCTAGACACGCTTAAAGAAGCAGTCGAACGCTTGAAAGCATTTATGGGTAGTGAGAATGATTGA

Upstream 100 bases:

>100_bases
TTGGCCGTTATCAAGATAAGCCAATCTGGGAAGTTAAGTCAGGATCTGATTTTTATCTAGTAGATTTTGAAACAGGAGCA
TTGGTCAACAAGGAGGGCCT

Downstream 100 bases:

>100_bases
TCATTTTGAGATTAAGGTAAAGGATTTACAAATTTCAGAAGGATTTTATAGGAGTTTTCTCGCTCCTTTGGACTATAAAT
TGGCTTTTAAGACTAGTTCT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSY
FERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQ
GAFYLFPNVKKAMEMKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND

Sequences:

>Translated_395_residues
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSY
FERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQ
GAFYLFPNVKKAMEMKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
>Mature_395_residues
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSY
FERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQ
GAFYLFPNVKKAMEMKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=27.020202020202, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=27.020202020202, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=27.5, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI56713256, Length=320, Percent_Identity=27.5, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=22.976501305483, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=25.4125412541254, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=24.1192411924119, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=24.1192411924119, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4885351, Length=385, Percent_Identity=26.7532467532467, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=26.5027322404372, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=26.4248704663212, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788627, Length=382, Percent_Identity=26.9633507853403, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787909, Length=369, Percent_Identity=22.7642276422764, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=422, Percent_Identity=27.2511848341232, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=28.0104712041885, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=409, Percent_Identity=27.6283618581907, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=409, Percent_Identity=27.6283618581907, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=25.706940874036, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320317, Length=350, Percent_Identity=26.5714285714286, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=344, Percent_Identity=21.2209302325581, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573069, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646114, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573067, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573065, Length=312, Percent_Identity=27.8846153846154, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859735, Length=408, Percent_Identity=23.0392156862745, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641770, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641760, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641768, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641766, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641764, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI45551451, Length=414, Percent_Identity=25.8454106280193, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43003; Mature: 43003

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGR
CCCCHHHHHHHCCEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCC
ASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVII
CEEEEEECCCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHCCCCCCEEE
PTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAARTDKTKVLVLNSPSNPTGMI
CCCCEECCCCEEEECCCCEEEEEECCCCEEEEEHHHHHHCCCCCEEEEEEECCCCCCEEE
YTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
EEHHHHHEECCEEEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCEEEEECCCHHE
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEER
EECCEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAMEMKGYTDVTDFTTAILEEAEVALVTGA
HHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEC
GFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGR
CCCCHHHHHHHCCEEEECCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCC
ASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVII
CEEEEEECCCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHCCCCCCEEE
PTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAARTDKTKVLVLNSPSNPTGMI
CCCCEECCCCEEEECCCCEEEEEECCCCEEEEEHHHHHHCCCCCEEEEEEECCCCCCEEE
YTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTY
EEHHHHHEECCEEEECCEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCEEEEECCCHHE
AMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEER
EECCEEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAMEMKGYTDVTDFTTAILEEAEVALVTGA
HHHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEC
GFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]