Click here to switch to the map view.

The map label for this gene is atpA [H]

Identifier: 221232222

GI number: 221232222

Start: 1427345

End: 1428850

Strand: Reverse

Name: atpA [H]

Synonym: SPN23F_14740

Alternate gene names: 221232222

Gene position: 1428850-1427345 (Counterclockwise)

Preceding gene: 221232223

Following gene: 221232221

Centisome position: 64.32

GC content: 44.42

Gene sequence:

>1506_bases
TTGGCAATTAACGCACAAGAAATCAGCGCTTTAATTAAGCAACAAATTGAAAATTTCAAACCCAATTTTGATGTGACTGA
AACAGGTGTTGTAACCTATATCGGGGACGGTATCGCGCGTGCTCACGGCCTTGAAAATGTCATGAGTGGAGAGTTGTTGA
ATTTTGAAAACGGCTCTTATGGTATGGCTCAAAACTTGGAGTCAACAGACGTTGGTATTATCATCCTAGGTGACTTTACA
GATATCCGTGAAGGCGATACAATCCGCCGTACAGGGAAAATCATGGAAGTCCCTGTAGGTGAAAGTCTGATTGGTCGTGT
TGTGGATCCGCTTGGTCGTCCAGTTGACGGTCTTGGAGAAATCCACACTGATAAAACTCGTCCAGTAGAAGCACCAGCTC
CTGGTGTTATGCAACGTAAGTCTGTTTCAGAACCATTGCAAACTGGTTTGAAAGCTATTGACGCCCTTGTACCGATTGGT
CGTGGTCAACGTGAGTTGATTATCGGTGACCGTCAGACAGGGAAAACAACCATTGCGATTGATACAATCTTGAACCAAAA
AGATCAAGATATGATCTGTATCTACGTCGCGATTGGACAAAAAGAATCAACAGTTCGTACGCAAGTAGAAACACTTCGTC
AGTACGGTGCCTTGGACTACACAATCGTTGTGACAGCCTCTGCTTCACAACCATCTCCATTGCTCTTCCTAGCTCCTTAT
ACTGGGGTCGCTATGGCGGAAGAATTTATGTATCAAGGTAAGCATGTTTTGATTGTATACGATGATCTATCAAAACAAGC
GGTAGCTTATCGTGAACTGTCGCTCTTGCTTCGTCGTCCTCCAGGTCGTGAAGCCTTCCCAGGGGATGTTTTCTATCTCC
ACAGCCGTTTGCTTGAGCGCTCAGCTAAAGTTTCTGATGAACTTGGTGGTGGATCAATTACAGCCCTACCATTTATCGAG
ACACAAGCAGGAGATATCTCAGCCTATATCGCAACCAACGTGATTTCTATCACTGATGGACAAATCTTCCTTGGCGATGG
CCTCTTCAATGCAGGTATTCGTCCAGCCATCGATGCGGGTTCATCTGTATCTCGTGTAGGTGGTTCTGCACAAATCAAAG
CCATGAAGAAGGTTGCTGGTACACTTCGTATCGACCTTGCTTCATACCGTGAGTTGGAAGCCTTTACTAAGTTTGGTTCT
GACTTGGACGCAGCAACACAGGCTAAGTTGAACCGTGGACGTCGTACCGTTGAGGTCTTGAAACAACCTGTTCACAAACC
ATTACCTGTTGAGAAACAAGTAACCATTCTTTATGCTTTGACACATGGTTTCTTGGATACTGTTCCAGTAGATGATATTG
TTCGTTTCGAGGAAGAGTTCCATGCCTTCTTTGATGCTCAACATCCAGAGATTTTGGAAACCATTCGTGATACAAAAGAC
TTGCCAGAAGAAGCAGTCTTGGATGCTGCGATTACAGAGTTTCTCAATCAATCTAGCTTCCAATAA

Upstream 100 bases:

>100_bases
GTGGTTTTGTCATTTTTGCCAATCACAAGACAATTGATGTGAGTATTAAACAACAACTTAAAGTTGTTAAAGAAAATTTG
AAATAGAAAGTGGTGTTCTT

Downstream 100 bases:

>100_bases
GAATAGAGGTGTCAGATGGCAGTGTCTCTAAATGATATTAAAACAAAAATCGCCTCAACAAAAAATACGAGTCAAATCAC
TAATGCCATGCAAATGGTAT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFT
DIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
TGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGS
DLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
LPEEAVLDAAITEFLNQSSFQ

Sequences:

>Translated_501_residues
MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFT
DIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
TGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGS
DLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
LPEEAVLDAAITEFLNQSSFQ
>Mature_500_residues
AINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTD
IREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGR
GQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPYT
GVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIET
QAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSD
LDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKDL
PEEAVLDAAITEFLNQSSFQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=499, Percent_Identity=57.5150300601202, Blast_Score=569, Evalue=1e-162,
Organism=Homo sapiens, GI4757810, Length=499, Percent_Identity=57.5150300601202, Blast_Score=569, Evalue=1e-162,
Organism=Homo sapiens, GI19913426, Length=305, Percent_Identity=29.1803278688525, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI19913428, Length=301, Percent_Identity=28.9036544850498, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI32189394, Length=375, Percent_Identity=24.5333333333333, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI19913424, Length=240, Percent_Identity=28.3333333333333, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790172, Length=495, Percent_Identity=53.3333333333333, Blast_Score=532, Evalue=1e-152,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=33.4558823529412, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790170, Length=383, Percent_Identity=25.3263707571802, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=56.7729083665339, Blast_Score=570, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=56.7729083665339, Blast_Score=569, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=52.7888446215139, Blast_Score=513, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17510931, Length=384, Percent_Identity=27.34375, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=298, Percent_Identity=28.1879194630872, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=429, Percent_Identity=23.0769230769231, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=237, Percent_Identity=28.6919831223629, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71988068, Length=75, Percent_Identity=37.3333333333333, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=499, Percent_Identity=55.1102204408818, Blast_Score=553, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=29.1803278688525, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=372, Percent_Identity=24.7311827956989, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=56.039603960396, Blast_Score=559, Evalue=1e-159,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24638766, Length=409, Percent_Identity=25.1833740831296, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28574560, Length=391, Percent_Identity=25.3196930946292, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24583988, Length=355, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583986, Length=355, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583984, Length=355, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129479, Length=240, Percent_Identity=28.3333333333333, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24583992, Length=249, Percent_Identity=28.5140562248996, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54676; Mature: 54545

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSY
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCC
GMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGE
HHHCCCCCCCEEEEEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCC
IHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
EHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
TGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLER
CCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAG
HHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCCCCCCCCCCC
SSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVL
CCHHHCCCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
HHHCCCCCCCCHHEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
LPEEAVLDAAITEFLNQSSFQ
CCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSY
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCC
GMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGE
HHHCCCCCCCEEEEEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCC
IHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
EHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
TGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLER
CCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAG
HHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCCCCCCCCCCC
SSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVL
CCHHHCCCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
HHHCCCCCCCCHHEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
LPEEAVLDAAITEFLNQSSFQ
CCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA