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The map label for this gene is ptsK

Identifier: 221232153

GI number: 221232153

Start: 1346487

End: 1347422

Strand: Reverse

Name: ptsK

Synonym: SPN23F_13780

Alternate gene names: 221232153

Gene position: 1347422-1346487 (Counterclockwise)

Preceding gene: 221232154

Following gene: 221232152

Centisome position: 60.66

GC content: 43.7

Gene sequence:

>936_bases
ATGTCGGTTTTAGTAAAAGAAGTGATTGAAAAGCTTAGACTAGACATTGTCTATGGTGAACCAGAGTTGCTTGAAAAGGA
AATCAATACAGCGGATATTACGCGACCTGGTCTTGAAATGACAGGCTATTTTGACTACTATACACCAGAGCGGATTCAAC
TTTTGGGGATGAAGGAGTGGTCTTATCTGATCAGCATGCCTTCCAACAGCCGTTATGAAGTTTTGAAAAAAATGTTTCTA
CCTGAGACACCAGCAGTCATTGTTGCTCGTGGTTTGGTGGTTCCAGAGGAGATGTTAAAGGCTGCTAGAGAATGTAAGAT
TGCTATTTTAACCAGCCGTGCAGCTACCAGTCGTTTATCTGGAGAGTTATCTAGCTATCTGGATTCTCGTTTGGCAGAAC
GTACCAGTGTGCACGGTGTCTTGATGGATATTTATGGGATGGGCGTCTTGATTCAGGGAGATAGTGGAATTGGTAAGAGC
GAGACAGGTCTTGAGCTTGTCAAACGTGGTCACCGTTTGGTAGCCGATGACCGTGTCGATATCTTTGCCAAGGATGAGAT
TACTCTCTGGGGTGAACCAGCTGAAATTTTGAAACACTTGATTGAAATTCGTGGGGTTGGTATTATCGATGTTATGAGTC
TCTACGGTGCGAGTGCTGTCAAGGATTCTTCACAGGTTCAGCTTGCTGTCTATTTGGAAAATTACGATACACATAAGACC
TTTGATCGTCTTGGAAACAATGCAGAGGAACTTGAAGTTTCTGGCGTAGCCATTCCTCGTATTCGTATTCCAGTTAAAAC
AGGTCGTAATATCTCTGTTGTGATTGAGGCAGCTGCCATGAATTATCGTGCCAAGGAAATGGGCTTTGATGCGACCCGTT
TGTTCGACGAACGACTGACAAGTCTCATTGCTCGAAATGAGGTGCAAAATGCTTGA

Upstream 100 bases:

>100_bases
CTTTTTCTTTTAAATAAATACTCCAAAGCCTGCAAAAATCTGAAACTTCCTCCTACAATTTGATATAATAGAGAGAAGAA
CTCATTTGAAGGAGGAAATG

Downstream 100 bases:

>100_bases
TCCAATTGCTATTCAACTAGGACCCCTAGCCATTCGTTGGTATGCCTTATGTATTGTGACAGGCTTGATTCTTGCGGTTT
ATTTGACCATGAAAGAAGCA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFL
PETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA

Sequences:

>Translated_311_residues
MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFL
PETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA
>Mature_310_residues
SVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLP
ETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSE
TGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKTF
DRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_STRPN (Q97Q18)

Other databases:

- EMBL:   AE005672
- PIR:   F95164
- RefSeq:   NP_345871.1
- ProteinModelPortal:   Q97Q18
- SMR:   Q97Q18
- EnsemblBacteria:   EBSTRT00000026603
- GeneID:   931419
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_1413
- TIGR:   SP_1413
- GeneTree:   EBGT00050000027588
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   SPNE170187-1:SP_1413-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 34728; Mature: 34596

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: ACT_SITE 139-139 ACT_SITE 160-160 ACT_SITE 178-178 ACT_SITE 244-244

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEW
CCHHHHHHHHHHCEEEEECCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCC
SYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLS
EEEEECCCCCHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHCEEEEEECHHHHHHHH
GELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCEE
IFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
EEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCEEEEEEEECCCCHHH
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLT
HHHHCCCHHHEEECCEEECEEEEEECCCCCEEEEEEEHHHCCHHHHHCCHHHHHHHHHHH
SLIARNEVQNA
HHHHHHHCCCC
>Mature Secondary Structure 
SVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEW
CHHHHHHHHHHCEEEEECCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCC
SYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLS
EEEEECCCCCHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHCEEEEEECHHHHHHHH
GELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCEE
IFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
EEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCEEEEEEEECCCCHHH
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLT
HHHHCCCHHHEEECCEEECEEEEEECCCCCEEEEEEEHHHCCHHHHHCCHHHHHHHHHHH
SLIARNEVQNA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916