Click here to switch to the map view.

The map label for this gene is aldB [H]

Identifier: 221232132

GI number: 221232132

Start: 1329984

End: 1330715

Strand: Reverse

Name: aldB [H]

Synonym: SPN23F_13560

Alternate gene names: 221232132

Gene position: 1330715-1329984 (Counterclockwise)

Preceding gene: 221232134

Following gene: 221232131

Centisome position: 59.91

GC content: 45.08

Gene sequence:

>732_bases
ATGGATAAGAACGTGCAGGAACCAGTGAAATTATTTCAATACAATACTCTTGGAGCCTTGATGGCTGGCCTTTATGGTGG
TACTATGACAGTAGGAGAATTGCTAGAACATGGTGACCTTGGTTTGGGAACCTTGGATTCCATTGATGGGGAATTGATTG
TCTTGGATGGCAAGGCTTATCAGGCCAAAGGGTCAGGAGACCAGCCAGAAATTGTGGAAGTGTCACCAGATGCCCTTATT
CCTTACGCTGCAGTGGTACCGCATCAGGCAGAGGTCATTTTCCGCCAGCGCTTTGAGATGACAGACAAGGAATTGAAAGA
ACGAATTGAGTCTTATTATGATGGGGAAAATCTTTTCCGCTCTATCAAGATTCGGGGGGAATTTTTACATATGCATGTGC
GTATGATTCCTAAGTCAACACCCGATACCAAGTTTGCTGATGTCGCAACCCATCAACCGGAATATAGTCGTGACAATGTT
GCGGGGACTATTGTTGGTTTCTGGACGCCTGAGATTTTCCATGGGGTCAGTGTGGCAGGCTACCATCTGCACTTCATATC
AGATGATTTGACCTTCGGTGGACATGTCATGGATTTTGTCATCAAGGAAGGCATTATCGAGGTGGGAGCAGTTGACCAGT
TGGACCAACGTTTCCCAGTCCAAGACCGTCAATACTTGTTTGCTAAGTTCAATGTTGACGAGATGAAAAAAGATATTGAA
AAGGCAGAATAG

Upstream 100 bases:

>100_bases
TCCTTCTTGGCAATGTCTAGAGCGTTTCTCTCGTTCACATCTAGGGGCAAATGTGGTATACTTAGGAGTAAGATTTATAG
AATAACAGACAAGAAAGTGA

Downstream 100 bases:

>100_bases
GAGAAGAAAATGACCATTCATATCATTATTACCATGTTGCTGTTGCTAGCTTTTCTGATAGGAAGCATTTGGTTTGCCAA
AAAGAAATACCAGATTAATC

Product: alpha-acetolactate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGTLDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALI
PYAAVVPHQAEVIFRQRFEMTDKELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRFPVQDRQYLFAKFNVDEMKKDIE
KAE

Sequences:

>Translated_243_residues
MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGTLDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALI
PYAAVVPHQAEVIFRQRFEMTDKELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRFPVQDRQYLFAKFNVDEMKKDIE
KAE
>Mature_243_residues
MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGTLDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALI
PYAAVVPHQAEVIFRQRFEMTDKELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRFPVQDRQYLFAKFNVDEMKKDIE
KAE

Specific function: Converts acetolactate into acetoin. Regulates leucine and valine biosynthesis by diverting the flux of alpha- acetolactate towards acetoin when the branched-chain amino acids are present in high concentration [H]

COG id: COG3527

COG function: function code Q; Alpha-acetolactate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-acetolactate decarboxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005128 [H]

Pfam domain/function: PF03306 AAL_decarboxy [H]

EC number: =4.1.1.5 [H]

Molecular weight: Translated: 27312; Mature: 27312

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGTLDSIDGELIVLDGKAY
CCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEE
QAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTDKELKERIESYYDGENLFR
ECCCCCCCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
SIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNVAGTIVGFWTPEIFHGVSVAG
HHHCCCEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEECHHHHCCCEEEE
YHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRFPVQDRQYLFAKFNVDEMKKDIE
EEEEEECCCCCCCHHHHHHHHHHCCHHCCCHHHHHHCCCCCCCEEEEEECCHHHHHHHHH
KAE
HCC
>Mature Secondary Structure
MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGTLDSIDGELIVLDGKAY
CCCCHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEE
QAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTDKELKERIESYYDGENLFR
ECCCCCCCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHH
SIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNVAGTIVGFWTPEIFHGVSVAG
HHHCCCEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEECHHHHCCCEEEE
YHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRFPVQDRQYLFAKFNVDEMKKDIE
EEEEEECCCCCCCHHHHHHHHHHCCHHCCCHHHHHHCCCCCCCEEEEEECCHHHHHHHHH
KAE
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12753249 [H]