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The map label for this gene is aroE [H]

Identifier: 221232118

GI number: 221232118

Start: 1312967

End: 1313821

Strand: Reverse

Name: aroE [H]

Synonym: SPN23F_13420

Alternate gene names: 221232118

Gene position: 1313821-1312967 (Counterclockwise)

Preceding gene: 221232119

Following gene: 221232117

Centisome position: 59.15

GC content: 43.27

Gene sequence:

>855_bases
ATGAAGCTTGATGGCTATACACGTTTAGCTGCAGTTGTTGCCAATCCTATTAAGCATTCTATTTCTCCCTTCATCCACAA
TAGAGCCTTTGAGGCGACAGCTACCAACGGTGCTTATGTGGCTTGGGAGATTGAAGCGAGTGACTTGGCAGAAACAGTGG
CCAATATTCGTCGCTACCAGATGTTTGGCATCAATCTGTCCATGCCCTATAAGGAGCAGGTGATTCCTTATTTGGATAAG
CTGAGCGATGAAGCGCGCTTGATTGGTGCGGTTAATACGGTTGTCAATGAGAATGGCAATTTAATTGGATATAATACAGA
TGGCAAGGGATTTTTTAAGTGCTTGCCTTCTTTTACAATTTCAGGTAAAAAGATGACCCTGCTGGGTGCAGGTGGTGCGG
CTAAATCAATCTTGGCACAGGCTATTTTGGATGGCGTCAGTCAGATTTCGGTCTTTGTTCGTTCAGTTTCTATGGAAAAA
ACAAGACCTTACCTAGACAAGTTACAGGAGCAAACAGGCTTTAAAGTGGACTTGTATGCTTTAGAAAATGTTTCTGAACT
GCAAGCAAGGATTGTCGAGTCGGATTTACTGGTCAATGCCACCAGTGTGGGCATGGATGGTCAATCATCCCCAGTTCCTG
AAAGCATCAATTTGCCAGAAACTATCTTGGTGGCAGATATTATTTATCAACCCTTTGAAACGCCATTTTTAAAATGGGCC
AGAAGTCAGGGCAAACCAGCGGTTAATGGTCTGGGAATGTTGCTCTATCAAGCTGCAGAAGCTTTTCAACTGTGGACAGG
CAAGGAAATGCCAACAGAAGAGATTTGGCAGTCTTTAACAGAAAAATACCAATAA

Upstream 100 bases:

>100_bases
GATGTGACTGGTTCGAGTTGGTCTTTTGCCAGTCTGGATGAGGTTAGTGCCCCTGGGCAGATTTCTCTAGCTAGCATGAA
AAAAATCAGGGAGATTTTGG

Downstream 100 bases:

>100_bases
AGAAAAGGAGATTCTCCTATGAAAATCAGAATCGATATTCCTCATCATCCTTATGATATTCAGATTGAAAAAGGTTGTCT
GGCTCAGGCTGGTCAATGGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDK
LSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
TRPYLDKLQEQTGFKVDLYALENVSELQARIVESDLLVNATSVGMDGQSSPVPESINLPETILVADIIYQPFETPFLKWA
RSQGKPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ

Sequences:

>Translated_284_residues
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDK
LSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
TRPYLDKLQEQTGFKVDLYALENVSELQARIVESDLLVNATSVGMDGQSSPVPESINLPETILVADIIYQPFETPFLKWA
RSQGKPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
>Mature_284_residues
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDK
LSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
TRPYLDKLQEQTGFKVDLYALENVSELQARIVESDLLVNATSVGMDGQSSPVPESINLPETILVADIIYQPFETPFLKWA
RSQGKPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=277, Percent_Identity=35.7400722021661, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1789675, Length=276, Percent_Identity=36.5942028985507, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=291, Percent_Identity=25.4295532646048, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31283; Mature: 31283

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLAETVANIRRYQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECHHHHHHHHHHHHHHE
MFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTI
EEECEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCEE
SGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLYA
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LENVSELQARIVESDLLVNATSVGMDGQSSPVPESINLPETILVADIIYQPFETPFLKWA
CCCHHHHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RSQGKPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLAETVANIRRYQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECHHHHHHHHHHHHHHE
MFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTI
EEECEECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCEE
SGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLYA
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
LENVSELQARIVESDLLVNATSVGMDGQSSPVPESINLPETILVADIIYQPFETPFLKWA
CCCHHHHHHHHHHHHHEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHH
RSQGKPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA