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The map label for this gene is cat

Identifier: 221232041

GI number: 221232041

Start: 1228032

End: 1228682

Strand: Reverse

Name: cat

Synonym: SPN23F_12590

Alternate gene names: 221232041

Gene position: 1228682-1228032 (Counterclockwise)

Preceding gene: 221232042

Following gene: 221232039

Centisome position: 55.31

GC content: 30.41

Gene sequence:

>651_bases
ATGAACTTTAATAAAATTGATTTAGACAATTGGAAGAGAAAAGAGATATTTAATCATTATTTGAACCAACAAACGACTTT
TAGTATAACCACAGAAATTGATATTAGTGTTTTATACCGAAACATAAAACAAGAAGGATATAAATTTTACCCTGCATTTA
TTTTCTTAGTGACAAGGGTGATAAACTCAAATACAGCTTTTAGAACTGGTTACAATAGCGACGGAGAGTTAGGTTATTGG
GATAAGTTAGAGCCACTTTATACAATTTTTGATGGTGTATCTAAAACATTCTCTGGTATTTGGACTCCTGTAAAGAATGA
CTTCAAAGAGTTTTATGATTTATACCTTTCTGATGTAGAGAAATATAATGGTTCGGGGAAATTGTTTCCCAAAACACCTA
TACCTGAAAATGCTTTTTCTCTTTCTATTATTCCATGGACTTCATTTACTGGGTTTAACTTAAATATCAATAATAATAGT
AATTACCTTCTACCCATTATTACAGCAGGAAAATTCATTAATAAAGGTAATTCAATATATTTACCGCTATCTTTACAGGT
ACATCATTCTGTTTGTGATGGTTATCATGCAGGATTGTTTATGAACTCTATTCAGGAATTGTCAGATAGGCCTAATGACT
GGCTTTTATAA

Upstream 100 bases:

>100_bases
CAGTAATATTGACTTTTAAAAAAGGATTGATTCTAATGAAGAAAGCAGACAAGTAAGCCTCCTAAATTCACTTTAGATAA
AAATTTAGGAGGCATATCAA

Downstream 100 bases:

>100_bases
TATGAGATAATGCCGACTGTACTTTTTACAGTCGGTTTTCTAATGTCACTAACCTGCCCCGTTAGTTGAAGAAGGTTTTT
ATATTACAGCTCCAGATCCA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: CAT

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNFNKIDLDNWKRKEIFNHYLNQQTTFSITTEIDISVLYRNIKQEGYKFYPAFIFLVTRVINSNTAFRTGYNSDGELGYW
DKLEPLYTIFDGVSKTFSGIWTPVKNDFKEFYDLYLSDVEKYNGSGKLFPKTPIPENAFSLSIIPWTSFTGFNLNINNNS
NYLLPIITAGKFINKGNSIYLPLSLQVHHSVCDGYHAGLFMNSIQELSDRPNDWLL

Sequences:

>Translated_216_residues
MNFNKIDLDNWKRKEIFNHYLNQQTTFSITTEIDISVLYRNIKQEGYKFYPAFIFLVTRVINSNTAFRTGYNSDGELGYW
DKLEPLYTIFDGVSKTFSGIWTPVKNDFKEFYDLYLSDVEKYNGSGKLFPKTPIPENAFSLSIIPWTSFTGFNLNINNNS
NYLLPIITAGKFINKGNSIYLPLSLQVHHSVCDGYHAGLFMNSIQELSDRPNDWLL
>Mature_216_residues
MNFNKIDLDNWKRKEIFNHYLNQQTTFSITTEIDISVLYRNIKQEGYKFYPAFIFLVTRVINSNTAFRTGYNSDGELGYW
DKLEPLYTIFDGVSKTFSGIWTPVKNDFKEFYDLYLSDVEKYNGSGKLFPKTPIPENAFSLSIIPWTSFTGFNLNINNNS
NYLLPIITAGKFINKGNSIYLPLSLQVHHSVCDGYHAGLFMNSIQELSDRPNDWLL

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CAT1_STAAU (P00485)

Other databases:

- EMBL:   V01277
- EMBL:   K01998
- EMBL:   X51450
- PIR:   A00568
- RefSeq:   NP_040437.1
- RefSeq:   YP_001718362.1
- RefSeq:   YP_001718364.1
- ProteinModelPortal:   P00485
- SMR:   P00485
- GeneID:   4594904
- GeneID:   6155849
- GeneID:   6155852
- ProtClustDB:   CLSK687527
- BRENDA:   2.3.1.28
- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- Gene3D:   G3DSA:3.30.559.10
- PIRSF:   PIRSF000440
- ProDom:   PD002660

Pfam domain/function: PF00302 CAT

EC number: =2.3.1.28

Molecular weight: Translated: 25040; Mature: 25040

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00100 CAT

Important sites: ACT_SITE 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNKIDLDNWKRKEIFNHYLNQQTTFSITTEIDISVLYRNIKQEGYKFYPAFIFLVTRV
CCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHH
INSNTAFRTGYNSDGELGYWDKLEPLYTIFDGVSKTFSGIWTPVKNDFKEFYDLYLSDVE
HCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KYNGSGKLFPKTPIPENAFSLSIIPWTSFTGFNLNINNNSNYLLPIITAGKFINKGNSIY
HHCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCHHHCCCCEEE
LPLSLQVHHSVCDGYHAGLFMNSIQELSDRPNDWLL
EEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNFNKIDLDNWKRKEIFNHYLNQQTTFSITTEIDISVLYRNIKQEGYKFYPAFIFLVTRV
CCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHH
INSNTAFRTGYNSDGELGYWDKLEPLYTIFDGVSKTFSGIWTPVKNDFKEFYDLYLSDVE
HCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KYNGSGKLFPKTPIPENAFSLSIIPWTSFTGFNLNINNNSNYLLPIITAGKFINKGNSIY
HHCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCHHHCCCCEEE
LPLSLQVHHSVCDGYHAGLFMNSIQELSDRPNDWLL
EEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6950931; 6202672; 2326208