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The map label for this gene is relA [H]

Identifier: 221232036

GI number: 221232036

Start: 1223282

End: 1223848

Strand: Reverse

Name: relA [H]

Synonym: SPN23F_12540

Alternate gene names: 221232036

Gene position: 1223848-1223282 (Counterclockwise)

Preceding gene: 221232037

Following gene: 221232035

Centisome position: 55.1

GC content: 28.22

Gene sequence:

>567_bases
ATGACAAATGCCAAAGAATTCGCATTAACTGCTCACAAAAATCAAACAAGAAAAGGGAAAATCACACCTTATTCATTTCA
CTTATTTTTGGTCAATAATATATTAGAAACCCTAACAGAAGATCCTCATATTATAGCTACCGGATGGTTACATGATACTG
TTGAAGATACCGATGTCAGTCTTGAAGATATTAAACAAGAATTTAATGATGAAATTTATTCATATATGTCTTTGGAATCT
GAAGATAAATCAATTAAAGATTGGCAAACTCGTAAAGAGCTTCAATTGGCAAAATTTCGAGAAGCAGCAGAAGATGAGTC
GCTAAGAAAAGTTTTACTTGTAACTTTTTCTGATAAATTAGCAAATTTAATGGAACTGTATCAAGATTACTTAATAATTG
GTGGTTTACTATGGGACCGTTTTAATTCAAAGGATCCGAAAAAACAACGATGGTACTTTAACGAGTTTTATAAAATCTTT
AAAGATAACCAAGATTTATTTTCGAAAAACAAAGATATTTTAAATAACTATAAAGAAATTTTAAAGCTTTTATTTTATAA
CAATTAA

Upstream 100 bases:

>100_bases
AAGAGTAGTGTATGTTGTTGATTAACTTTACTAAATTTTTAAATTTAAAAGTACAATAAAAAATATATATTCAACAGAGA
CAAAAGGAGGAAATAGTTTT

Downstream 100 bases:

>100_bases
AAATATGTTTTTAAAATTATCTTTTAATTAAATGTAAATAGAAAGGATACAAATGAATAAACCAATAGCAGCTATATTTG
ATATCGACGGAACAATTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MTNAKEFALTAHKNQTRKGKITPYSFHLFLVNNILETLTEDPHIIATGWLHDTVEDTDVSLEDIKQEFNDEIYSYMSLES
EDKSIKDWQTRKELQLAKFREAAEDESLRKVLLVTFSDKLANLMELYQDYLIIGGLLWDRFNSKDPKKQRWYFNEFYKIF
KDNQDLFSKNKDILNNYKEILKLLFYNN

Sequences:

>Translated_188_residues
MTNAKEFALTAHKNQTRKGKITPYSFHLFLVNNILETLTEDPHIIATGWLHDTVEDTDVSLEDIKQEFNDEIYSYMSLES
EDKSIKDWQTRKELQLAKFREAAEDESLRKVLLVTFSDKLANLMELYQDYLIIGGLLWDRFNSKDPKKQRWYFNEFYKIF
KDNQDLFSKNKDILNNYKEILKLLFYNN
>Mature_187_residues
TNAKEFALTAHKNQTRKGKITPYSFHLFLVNNILETLTEDPHIIATGWLHDTVEDTDVSLEDIKQEFNDEIYSYMSLESE
DKSIKDWQTRKELQLAKFREAAEDESLRKVLLVTFSDKLANLMELYQDYLIIGGLLWDRFNSKDPKKQRWYFNEFYKIFK
DNQDLFSKNKDILNNYKEILKLLFYNN

Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI25143118, Length=139, Percent_Identity=33.8129496402878, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650996, Length=124, Percent_Identity=36.2903225806452, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 22483; Mature: 22351

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAKEFALTAHKNQTRKGKITPYSFHLFLVNNILETLTEDPHIIATGWLHDTVEDTDVS
CCCCHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCCCCC
LEDIKQEFNDEIYSYMSLESEDKSIKDWQTRKELQLAKFREAAEDESLRKVLLVTFSDKL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ANLMELYQDYLIIGGLLWDRFNSKDPKKQRWYFNEFYKIFKDNQDLFSKNKDILNNYKEI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHH
LKLLFYNN
HHHHHCCC
>Mature Secondary Structure 
TNAKEFALTAHKNQTRKGKITPYSFHLFLVNNILETLTEDPHIIATGWLHDTVEDTDVS
CCCHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCCCCC
LEDIKQEFNDEIYSYMSLESEDKSIKDWQTRKELQLAKFREAAEDESLRKVLLVTFSDKL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ANLMELYQDYLIIGGLLWDRFNSKDPKKQRWYFNEFYKIFKDNQDLFSKNKDILNNYKEI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHH
LKLLFYNN
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9383190; 9384377 [H]