| Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
|---|---|
| Accession | NC_011900 |
| Length | 2,221,315 |
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The map label for this gene is hsdR [H]
Identifier: 221231346
GI number: 221231346
Start: 450918
End: 453251
Strand: Reverse
Name: hsdR [H]
Synonym: SPN23F_04630
Alternate gene names: 221231346
Gene position: 453251-450918 (Counterclockwise)
Preceding gene: 221231354
Following gene: 221231345
Centisome position: 20.4
GC content: 36.93
Gene sequence:
>2334_bases ATGGTTGAGTTTATAAAGTCTAAGAAAGAAATGAGTGAGGAGGATATTAAAGCAAATTTCATCACTCCTGCTATTGTATC CAAAGGATGGAAAAATGGTGAGCATATCGCTTACGAAGAATACTTCACTGATGGTCGAATTGAAGTTAGAGGAGATAAGG CTCGTCGTAAAGAAGGAAAAAAATCAGACTATTCACTGTATTACCAATTTGGAACTCGAATTGCAATTGTTGAGGCAAAG GATAATAAACACAGCGTTCGAGCAGGATTACAACAAGCTATTGAATATGGAGAGATTTTAGATGTTCCATTTGTTTATTC TTCGAATGGTGATGGCTTTATTGAACACGACCGTATCACGAGAGAAGAACGTGAGCTGGAGTTAGACGAATTCCCTACTC GTGAAGAATTATTTTCTCGTATGACGAAGGAAAAAGGATTGACGTACGAAATTACAGAAGCTATCTCAACTCCATACTAT ACAGACGCCTTCTCAATGAAAACGCCACGCTATTATCAGCAAATAGCTATCAACCGTACTATTGAAACAGTTGCCAGAGG ACAAAAACGAGTAATGTTTGTGATGGCAACAGGAACGGGGAAAACGTTCATGGCTTTTCAAATTATTCATCGCCTTCGAA AAGCTGGTTTGGCTAAACGAGTTTTATTCTTAGCGGATAGAAACATCTTAGTAGACCAAACGATGGCTGAAGACTTTAAG CCATTCGAAAAGGTAATGACGAAAATTACACCAAAACTTTTGACTGCTCCTGAAAAATTAAATTCTTTTGAAATTTATCT AGGGCTTTATCAGCAACTAACTGGTGAAGATGGAACTGAAACACATTATCAAAAATTTGATAAAGACTTCTTTGATTTAA TCGTAATTGATGAAGCGCACCGTGGTTCAGCTAAGGAAAACAGTAACTGGCGTAAGATAATTGATTATTTCAGTTCTGCG ACACAGATTGGGATGACCGCTACTCCTAAAGAAACCAAGAATGCTTCCAATACGGAATACTTTGGTGAGCCAATCTATAC TTATAGTTTAAAACAGGGAATCGAGGATGGTTTTTTGGCTCCATATCGTGTTATGAGGGTTAATTTAGATGTGGATGTGG ATGGTTATCGTCCAGAAACTGGAAAAGTTGATACTAACGGACAATTAATAGAAGATAGGTACTACGGCAGGAAAGATTTT GATAAAACCATTGTCATTGATGATAGAACGCAAAGAGTTGCCAAGTTTGTTTCTGATTATATGAAGCAAAACAATGCACG ATTTGATAAAACAATTGTTTTTTGTGTTGATATTGACCATGCCGAGCGAATGCGTGCTGCACTTGTAAAAGAGAATCTAG ACTTAGTCCAAGAAGACTATCGTTATGTCATGCAAGTAACTGGTGACAACGCTGAAGGAAAAGCTCAACTGGATAACTTT ATGGATGTCAATTCTAATTTTCCCGCTATGGTAACAACGTCTAAATTATTAACGACAGGAGTTAATGCTAAAACATGTCG TTTGATTGTTTTAGACTCTAATATCCAATCCATGACTGAATTTAAACAAATTATTGGTCGTGGCACACGTCTTTATCCTC AAAAGGGGAAAGAATTTTTTACGATTATTGATTTTCGAAATGTTACCAATTTGTTTGCTGACCCTGATTTTGATGGTGAG CCAGTGAAGGTGCTGGAAACAGGTGCGAAAACAGTCAGTGGTTCCACGCCCGGTTTCGTAGATGAGGAAGGTGACCCAGT AGAAAAATATATCGTTACAGACAAGCAGGTTACCATTCTTAATTCTACTGTTCAAGTATTGGATGAAAACGGGAAACTGA TTACCGAAAGCCTGACCGACTACACTCGGAAGAATATCTTAGGTAGCTACGCCACTTTGAACGATTTTATCACAGTTTGG CATACGGCGGATAAAAAGAAGCTTATCTTAGACGAACTTTATAAAAAAGGAGTTTATCTAGATGCTATTCGAGAGTCGGA GGGAATATCAGAACAAGAAATCGATGATTTTGATTTACTCCTAAAACTTGCCTATGGTCAAAAAGAATTAACCAAAACGG AACGTATCAATAAGCTCAAACAAAGCGGATATTTATATAAATATAGTGAGGAAGCGCGTGCTGTTTTGGAAATTTTACTG AACAAATACATGGATAAAGGTATTGGAGAACTCGAAAGCATTGAAACATTAAAACTTCCAGAATTTCAGATATATGGTGG AACCTTCAAAATCATCAATACTTATTTTGGAGATAAAAAACGATATTTACAAGCAATTAAAGAATTGGAGCAAGAGCTAT TTACAGTAGCTTAA
Upstream 100 bases:
>100_bases TTAGCAGAGTATTTTTATAAGTGTGATATAATAGAAGTATAATTTGTTCTGATAGTTTATTTTATGGAGAAGTAGATTTT TAGAATGCGGAGGATTCAAT
Downstream 100 bases:
>100_bases TGAAAGGAAAGTATGTCAATTACATCATTTGTAAAAAGAATTCAAGATATCACTCGAAACGATGCTGGTGTTAATGGTGA TGCTCAACGTATTGAGCAAA
Product: type I restriction-modification system R protein
Products: NA
Alternate protein names: R.EcoAI [H]
Number of amino acids: Translated: 777; Mature: 777
Protein sequence:
>777_residues MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAK DNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFK PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSA TQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIEDRYYGRKDF DKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF MDVNSNFPAMVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGE PVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVW HTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA
Sequences:
>Translated_777_residues MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAK DNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFK PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSA TQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIEDRYYGRKDF DKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF MDVNSNFPAMVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGE PVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVW HTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA >Mature_777_residues MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAK DNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFK PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSA TQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIEDRYYGRKDF DKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF MDVNSNFPAMVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGE PVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVW HTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA
Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]
COG id: COG4096
COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI226510991, Length=575, Percent_Identity=27.8260869565217, Blast_Score=151, Evalue=2e-37, Organism=Escherichia coli, GI1788511, Length=407, Percent_Identity=24.3243243243243, Blast_Score=81, Evalue=3e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014001 - InterPro: IPR001650 - InterPro: IPR014021 - InterPro: IPR006935 - InterPro: IPR013670 - InterPro: IPR007409 [H]
Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]
EC number: =3.1.21.3 [H]
Molecular weight: Translated: 89354; Mature: 89354
Theoretical pI: Translated: 5.16; Mature: 5.16
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGK CCHHHHHHHHCCHHHHHHHCCCHHHHHCCCCCCCEEEEHHHCCCCEEEECCCHHHHCCCC KSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRIT CCCCEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCCEECCCEEEECCCCCCEECCHHC REERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYYTDAFSMKTPRYYQQIAINRT CHHHHCCHHCCCCHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHH IETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFK HHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEHHHHHHHH PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAH HHHHHHHHHCHHHHCCHHHCCCEEEHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCC RGSAKENSNWRKIIDYFSSATQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLA CCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEEHHHHCCCCCCCC PYRVMRVNLDVDVDGYRPETGKVDTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDY CEEEEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHH MKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF HHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH MDVNSNFPAMVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFF HCCCCCCCCEEEHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEECCCCCCEEE TIIDFRNVTNLFADPDFDGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTIL EEEEHHHHHHHHCCCCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCHHHEEECCCEEEEE NSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYL HHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCHHHHHHHHHHCCCEE DAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL EEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHH NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA HHHHHCCCCCHHCCCEECCCCEEEECCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGK CCHHHHHHHHCCHHHHHHHCCCHHHHHCCCCCCCEEEEHHHCCCCEEEECCCHHHHCCCC KSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRIT CCCCEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCCEECCCEEEECCCCCCEECCHHC REERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYYTDAFSMKTPRYYQQIAINRT CHHHHCCHHCCCCHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHH IETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFK HHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEHHHHHHHH PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAH HHHHHHHHHCHHHHCCHHHCCCEEEHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCC RGSAKENSNWRKIIDYFSSATQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLA CCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEEHHHHCCCCCCCC PYRVMRVNLDVDVDGYRPETGKVDTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDY CEEEEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHH MKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF HHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH MDVNSNFPAMVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFF HCCCCCCCCEEEHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEECCCCCCEEE TIIDFRNVTNLFADPDFDGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTIL EEEEHHHHHHHHCCCCCCCCCHHHEECCCCCCCCCCCCCCCCCCCCHHHEEECCCEEEEE NSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYL HHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCHHHHHHHHHHCCCEE DAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL EEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHH NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA HHHHHCCCCCHHCCCEECCCCEEEECCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8412658 [H]