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The map label for this gene is dinB [H]

Identifier: 221231317

GI number: 221231317

Start: 413195

End: 414256

Strand: Reverse

Name: dinB [H]

Synonym: SPN23F_04310

Alternate gene names: 221231317

Gene position: 414256-413195 (Counterclockwise)

Preceding gene: 221231319

Following gene: 221231314

Centisome position: 18.65

GC content: 40.58

Gene sequence:

>1062_bases
ATGTTGATTTTTCCTTTGTTAAATGATTTGTCAAGAAAAATCATCCATATTGACATGGATGCCTTTTTTGCTGCAGTGGA
AATCAGGGATAATCCTAAACTCAGAGGAAAACCTGTCATTATTGGAAGCGACCCTCGGCAAACAGGTGGACGGGGAGTCG
TTTCTACCTGTAGTTATGAGGCAAGAGCTTTTGGTGTCCATTCTGCCATGAGTTCCAAGGAAGCTTATGAACGTTGTCCC
CAGGCTGTCTTTATCTCAGGGAATTATGAGAAATACAAGTCTGTGGGACTCCAGATTCGAGCTATTTTTAAGCGCTATAC
AGATTTGATTGAACCCATGAGCATTGACGAAGCCTATTTGGATGTGACAGAAAATAAACTCGGTATCAAGTCAGCGGTCA
AAATTGCTCGCCTCATTCAAAAAGATATCTGGCAAGAACTCCATCTAACTGCTTCCGCAGGCGTTTCTTACAACAAATTC
TTAGCTAAAATGGCGAGTGATTATCAAAAACCACATGGTTTGACAGTGATTCTACCTGAACAGGCTGAGGATTTTCTCAA
ACAAATGGATATTTCCAAATTTCATGGAGTAGGAAAAAAGACAGTAGAACGTCTTCATCAAATGGGCGTTTTTACTGGTG
CTGATTTACTTGAAGTTCCTGAGGTAACCCTAATAGACCGTTTTGGTAGACTAGGCTATGATCTGTATCGAAAGGCTCGT
GGCATTCACAACTCTCCAGTCAAATCCAATCGCATCCGTAAATCAATCGGCAAGGAGAAAACCTACGGGAAGATTCTCCT
TGCTGAGGAAGATATCAAAAAAGAGCTGACTCTTCTATCAGAAAAAGTCGCTCTCAATCTACATCAACAAGAAAAAGCTG
GAAAAATTGTCATTTTGAAAATCCGCTACGAGGACTTTTCAACTCTTACCAAACGAAAAAGTCTTGCTCAAAAAACACAA
GATGCTAGTCAGATAAGCCAAATAGCCCTGCAACTCTATGAAGAATTAAGCAAGAAAGAAAGAGGTGTCCGCCTATTGGG
GATTACCATGACTGGATTTTAA

Upstream 100 bases:

>100_bases
AGGAAGCTAGCCGCAGATTGCTCAAAACACTGTTTTGAGGTTGCAGATAGAGCTGACGTGGTTTGAAGAGATTTTCGAAG
AGTATAAAAAGGTGCTAGGC

Downstream 100 bases:

>100_bases
AGCTCAATGAAAATCAAAGAGCAAACTAGGAGGCTAGCCGCAGGCTGCTCAAAACACTGTTTTGAGGTTGCAGATAAAGC
TGACGCGGTTTGAAGAGATT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCP
QAVFISGNYEKYKSVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
GIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQ
DASQISQIALQLYEELSKKERGVRLLGITMTGF

Sequences:

>Translated_353_residues
MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCP
QAVFISGNYEKYKSVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
GIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQ
DASQISQIALQLYEELSKKERGVRLLGITMTGF
>Mature_353_residues
MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCP
QAVFISGNYEKYKSVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
GIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQ
DASQISQIALQLYEELSKKERGVRLLGITMTGF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=29.2899408284024, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=29.2035398230088, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI154350220, Length=300, Percent_Identity=28, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7705344, Length=115, Percent_Identity=44.3478260869565, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI5729982, Length=396, Percent_Identity=26.5151515151515, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1786425, Length=348, Percent_Identity=41.3793103448276, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1787432, Length=212, Percent_Identity=28.7735849056604, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=417, Percent_Identity=29.7362110311751, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=369, Percent_Identity=26.5582655826558, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=40, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193205702, Length=347, Percent_Identity=26.5129682997118, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19923006, Length=412, Percent_Identity=25, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI21355641, Length=408, Percent_Identity=27.4509803921569, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24644984, Length=408, Percent_Identity=27.4509803921569, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24668444, Length=127, Percent_Identity=33.8582677165354, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39881; Mature: 39881

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYE
CEEEHHHHHHHHHEEEEEHHHHEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCHHCCCH
ARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAIFKRYTDLIEPMSIDEAYL
HHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKFLAKMASDYQKPHGLTVILPE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECH
QAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
HHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHC
GIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKELTLLSEKVALNLHQQEKAGKIVILK
CCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
IRYEDFSTLTKRKSLAQKTQDASQISQIALQLYEELSKKERGVRLLGITMTGF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCC
>Mature Secondary Structure
MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYE
CEEEHHHHHHHHHEEEEEHHHHEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCHHCCCH
ARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAIFKRYTDLIEPMSIDEAYL
HHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
DVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKFLAKMASDYQKPHGLTVILPE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECH
QAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKAR
HHHHHHHHHCHHHHHCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHC
GIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKELTLLSEKVALNLHQQEKAGKIVILK
CCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
IRYEDFSTLTKRKSLAQKTQDASQISQIALQLYEELSKKERGVRLLGITMTGF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA