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The map label for this gene is engD [H]

Identifier: 220933169

GI number: 220933169

Start: 2555492

End: 2556586

Strand: Reverse

Name: engD [H]

Synonym: Hore_23370

Alternate gene names: 220933169

Gene position: 2556586-2555492 (Counterclockwise)

Preceding gene: 220933170

Following gene: 220933168

Centisome position: 99.16

GC content: 47.31

Gene sequence:

>1095_bases
ATGAAAATAGGAATTGTTGGACTACCCAATGTTGGAAAATCAACTCTATTCAATGCCTTAACCCGGGCCCGGGCCGATGC
TGCCAATTACCCTTTTTGTACTATTGACCCCAATGTCGGGGTTGTAAATGTCCCCGATCCCAGGCTGGAGGTTTTAAATG
AAATGTATCAACCGGCCAAAAAAACCCCGACTACCATTGAATTTGTTGATATCGCCGGACTGGTCAGGGGAGCCAGTAAG
GGAGAGGGTCTGGGCAACCAGTTTCTGGCCCATATCAGGGAGGTAGAGGCCATTGCCCAGGTGGTAAGGTGTTTTACTGA
TGAAAATGTAACCCATGTTGATGGTGAAATTGACCCGGTACGGGATATAGAAACCATCAATACTGAATTAATGCTTGCTG
ATCTGGCCACAGTGGAAAAAAGAATGGAAAAGACCTCCCGGATGGCTAAAAGTGGTGAAAAAAAATATAAAGAGGAATTA
AAGGTACTGGAAGAATTGAAAACAGCCCTGGCCGAAGGGAAAAGCATCAGACAGCTTGACCCGGGGGAAACGGGTAAAAG
GTTAATTAAGGAACTCAATCTCCTGACTGCCAAACCAACGATTTATATTGCCAATGTCAATGAAGAAGATATGATAGATC
CCTCTGGTAATAGACTTGTCAATGAAGTTAAGGAATATGCGGCCGGTGAAGGAGCCAGGGTGGTAGCCATCAGTGCCAAA
ATAGAGGCCGATCTGGCCGAGCTAGAAGAAGAGGAGGCTCGCCTTTTCATGGAAGAGCTGGGTCTTGAGGAATCAGGCCT
GGACAGGGTTATCAGGGCCGGTTATGCCCTGTTGGACCTTATTACCTTTTTTACCGCCGGGGAAAAGGAAGTCAGGGCCT
GGACGGTTAAAAGAGGGGCTACGGCTCCGGAGGCAGCCGGGAAGATCCATACCGATATGCAGCGGGGTTTTATCAGGGCC
GAGGTTATCAGTTATGAAGACCTGGTTAGAGCCGGGTCTGTAGCTAAAGTCAGGGAAGAAGGTCTCCTCCGCCTGGAAGG
CAAAGATTATATTGTTAAAGATGGGGATATCTGTTATTTCAGGTTCAATGTTTAA

Upstream 100 bases:

>100_bases
TAGTTATGATGCCCAGGCGTAAATTTGAAAAGAATGTTAAAGAAATTGTAGAAAGAGCAGGAGAATAAAAAGAGAAAATT
AGTGATTGAGGAGGAAGGTC

Downstream 100 bases:

>100_bases
GAACCGGGCAAAAAAATGTTGAAATCCCCGGGAGGCAATGCTATAATATAGAATGAATTGCATCCATGCTCTAATTTTAA
ATTGGGGCCGTCAGTCCACA

Product: GTP-binding protein YchF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKIGIVGLPNVGKSTLFNALTRARADAANYPFCTIDPNVGVVNVPDPRLEVLNEMYQPAKKTPTTIEFVDIAGLVRGASK
GEGLGNQFLAHIREVEAIAQVVRCFTDENVTHVDGEIDPVRDIETINTELMLADLATVEKRMEKTSRMAKSGEKKYKEEL
KVLEELKTALAEGKSIRQLDPGETGKRLIKELNLLTAKPTIYIANVNEEDMIDPSGNRLVNEVKEYAAGEGARVVAISAK
IEADLAELEEEEARLFMEELGLEESGLDRVIRAGYALLDLITFFTAGEKEVRAWTVKRGATAPEAAGKIHTDMQRGFIRA
EVISYEDLVRAGSVAKVREEGLLRLEGKDYIVKDGDICYFRFNV

Sequences:

>Translated_364_residues
MKIGIVGLPNVGKSTLFNALTRARADAANYPFCTIDPNVGVVNVPDPRLEVLNEMYQPAKKTPTTIEFVDIAGLVRGASK
GEGLGNQFLAHIREVEAIAQVVRCFTDENVTHVDGEIDPVRDIETINTELMLADLATVEKRMEKTSRMAKSGEKKYKEEL
KVLEELKTALAEGKSIRQLDPGETGKRLIKELNLLTAKPTIYIANVNEEDMIDPSGNRLVNEVKEYAAGEGARVVAISAK
IEADLAELEEEEARLFMEELGLEESGLDRVIRAGYALLDLITFFTAGEKEVRAWTVKRGATAPEAAGKIHTDMQRGFIRA
EVISYEDLVRAGSVAKVREEGLLRLEGKDYIVKDGDICYFRFNV
>Mature_364_residues
MKIGIVGLPNVGKSTLFNALTRARADAANYPFCTIDPNVGVVNVPDPRLEVLNEMYQPAKKTPTTIEFVDIAGLVRGASK
GEGLGNQFLAHIREVEAIAQVVRCFTDENVTHVDGEIDPVRDIETINTELMLADLATVEKRMEKTSRMAKSGEKKYKEEL
KVLEELKTALAEGKSIRQLDPGETGKRLIKELNLLTAKPTIYIANVNEEDMIDPSGNRLVNEVKEYAAGEGARVVAISAK
IEADLAELEEEEARLFMEELGLEESGLDRVIRAGYALLDLITFFTAGEKEVRAWTVKRGATAPEAAGKIHTDMQRGFIRA
EVISYEDLVRAGSVAKVREEGLLRLEGKDYIVKDGDICYFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=44.5652173913043, Blast_Score=324, Evalue=6e-89,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=38.7665198237885, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI24308117, Length=111, Percent_Identity=36.9369369369369, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=59.0659340659341, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1789574, Length=137, Percent_Identity=32.8467153284672, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=43.4426229508197, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17508313, Length=99, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=42.7027027027027, Blast_Score=286, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=39.5778364116095, Blast_Score=259, Evalue=6e-70,
Organism=Saccharomyces cerevisiae, GI6321649, Length=156, Percent_Identity=37.1794871794872, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321962, Length=148, Percent_Identity=27.7027027027027, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=43.9024390243902, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=43.9024390243902, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=43.9024390243902, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=41.4634146341463, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24585318, Length=138, Percent_Identity=31.8840579710145, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20129375, Length=121, Percent_Identity=33.0578512396694, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40245; Mature: 40245

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIVGLPNVGKSTLFNALTRARADAANYPFCTIDPNVGVVNVPDPRLEVLNEMYQPAK
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHC
KTPTTIEFVDIAGLVRGASKGEGLGNQFLAHIREVEAIAQVVRCFTDENVTHVDGEIDPV
CCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
RDIETINTELMLADLATVEKRMEKTSRMAKSGEKKYKEELKVLEELKTALAEGKSIRQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PGETGKRLIKELNLLTAKPTIYIANVNEEDMIDPSGNRLVNEVKEYAAGEGARVVAISAK
CCHHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECH
IEADLAELEEEEARLFMEELGLEESGLDRVIRAGYALLDLITFFTAGEKEVRAWTVKRGA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCC
TAPEAAGKIHTDMQRGFIRAEVISYEDLVRAGSVAKVREEGLLRLEGKDYIVKDGDICYF
CCCHHHCHHHHHHHHCHHHHHHHCHHHHHHCCCHHHHHHCCCEEECCCCEEEECCCEEEE
RFNV
EECC
>Mature Secondary Structure
MKIGIVGLPNVGKSTLFNALTRARADAANYPFCTIDPNVGVVNVPDPRLEVLNEMYQPAK
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHC
KTPTTIEFVDIAGLVRGASKGEGLGNQFLAHIREVEAIAQVVRCFTDENVTHVDGEIDPV
CCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
RDIETINTELMLADLATVEKRMEKTSRMAKSGEKKYKEELKVLEELKTALAEGKSIRQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PGETGKRLIKELNLLTAKPTIYIANVNEEDMIDPSGNRLVNEVKEYAAGEGARVVAISAK
CCHHHHHHHHHHHHEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECH
IEADLAELEEEEARLFMEELGLEESGLDRVIRAGYALLDLITFFTAGEKEVRAWTVKRGA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEEECCCC
TAPEAAGKIHTDMQRGFIRAEVISYEDLVRAGSVAKVREEGLLRLEGKDYIVKDGDICYF
CCCHHHCHHHHHHHHCHHHHHHHCHHHHHHCCCHHHHHHCCCEEECCCCEEEECCCEEEE
RFNV
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]